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Items: 1 to 20 of 101


Inhibition of the CXCL12/CXCR4 axis prevents periurethral collagen accumulation and lower urinary tract dysfunction in vivo.

Macoska JA, Wang Z, Virta J, Zacharias N, Bjorling DE.

Prostate. 2019 May;79(7):757-767. doi: 10.1002/pros.23781. Epub 2019 Feb 27.


CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling.

Rodríguez-Nieves JA, Patalano SC, Almanza D, Gharaee-Kermani M, Macoska JA.

PLoS One. 2016 Jul 19;11(7):e0159490. doi: 10.1371/journal.pone.0159490. eCollection 2016.


Obesity-induced diabetes and lower urinary tract fibrosis promote urinary voiding dysfunction in a mouse model.

Gharaee-Kermani M, Rodriguez-Nieves JA, Mehra R, Vezina CA, Sarma AV, Macoska JA.

Prostate. 2013 Jul;73(10):1123-33. doi: 10.1002/pros.22662. Epub 2013 Mar 26.


Proinflammatory CXCL12-CXCR4/CXCR7 Signaling Axis Drives Myc-Induced Prostate Cancer in Obese Mice.

Saha A, Ahn S, Blando J, Su F, Kolonin MG, DiGiovanni J.

Cancer Res. 2017 Sep 15;77(18):5158-5168. doi: 10.1158/0008-5472.CAN-17-0284. Epub 2017 Jul 7.


Resveratrol-Mediated Repression and Reversion of Prostatic Myofibroblast Phenoconversion.

Gharaee-Kermani M, Moore BB, Macoska JA.

PLoS One. 2016 Jul 1;11(7):e0158357. doi: 10.1371/journal.pone.0158357. eCollection 2016.


CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis.

Gharaee-Kermani M, Kasina S, Moore BB, Thomas D, Mehra R, Macoska JA.

PLoS One. 2012;7(11):e49278. doi: 10.1371/journal.pone.0049278. Epub 2012 Nov 16.


Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity.

Sun G, Yin Z, Liu N, Bian X, Yu R, Su X, Zhang B, Wang Y.

Biochem Biophys Res Commun. 2017 Nov 18;493(2):964-970. doi: 10.1016/j.bbrc.2017.09.108. Epub 2017 Sep 20.


Deficiency of the tumor promoter gene wip1 induces insulin resistance.

Armata HL, Chamberland S, Watts L, Ko HJ, Lee Y, Jung DY, Kim JK, Sluss HK.

Mol Endocrinol. 2015 Jan;29(1):28-39. doi: 10.1210/me.2014-1136.


CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet.

Kurita K, Ishikawa K, Takeda K, Fujimoto M, Ono H, Kumagai J, Inoue H, Yokoh H, Yokote K.

Sci Rep. 2019 Apr 16;9(1):6165. doi: 10.1038/s41598-019-42127-8.


Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells.

Heinrich EL, Lee W, Lu J, Lowy AM, Kim J.

J Transl Med. 2012 Apr 2;10:68. doi: 10.1186/1479-5876-10-68.


The chemokine receptors CXCR4/CXCR7 and their primary heterodimeric ligands CXCL12 and CXCL12/high mobility group box 1 in pancreatic cancer growth and development: finding flow.

Shakir M, Tang D, Zeh HJ, Tang SW, Anderson CJ, Bahary N, Lotze MT.

Pancreas. 2015 May;44(4):528-34. doi: 10.1097/MPA.0000000000000298. Review.


Dietary macronutrient content affects inflammatory and fibrotic factors in normal and obstructed bladders.

Adedeji TG, Olapade-Olaopa EO.

Life Sci. 2018 Oct 1;210:192-200. doi: 10.1016/j.lfs.2018.08.069. Epub 2018 Sep 4.


Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis.

Lo L, McLennan SV, Williams PF, Bonner J, Chowdhury S, McCaughan GW, Gorrell MD, Yue DK, Twigg SM.

J Hepatol. 2011 Aug;55(2):435-44. doi: 10.1016/j.jhep.2010.10.039. Epub 2010 Dec 22.


CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR.

Circelli L, Sciammarella C, Guadagno E, Tafuto S, del Basso de Caro M, Botti G, Pezzullo L, Aria M, Ramundo V, Tatangelo F, Losito NS, Ieranò C, D'Alterio C, Izzo F, Ciliberto G, Colao A, Faggiano A, Scala S.

Oncotarget. 2016 Apr 5;7(14):18865-75. doi: 10.18632/oncotarget.7738.


Meal pattern alterations associated with intermittent fasting for weight loss are normalized after high-fat diet re-feeding.

Gotthardt JD, Bello NT.

Physiol Behav. 2017 May 15;174:49-56. doi: 10.1016/j.physbeh.2017.02.046. Epub 2017 Mar 3.


Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility.

Hsiao JJ, Ng BH, Smits MM, Wang J, Jasavala RJ, Martinez HD, Lee J, Alston JJ, Misonou H, Trimmer JS, Wright ME.

BMC Cancer. 2015 Mar 31;15:204. doi: 10.1186/s12885-015-1201-5.


Relationship of the Chemokine, CXCL12, to Effects of Dietary Fat on Feeding-Related Behaviors and Hypothalamic Neuropeptide Systems.

Poon K, Barson JR, Ho HT, Leibowitz SF.

Front Behav Neurosci. 2016 Mar 21;10:51. doi: 10.3389/fnbeh.2016.00051. eCollection 2016.


Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet.

Boini KM, Zhang C, Xia M, Poklis JL, Li PL.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):839-46. doi: 10.1124/jpet.110.168815. Epub 2010 Jun 11.


Role of PAR2 in the Development of Lower Urinary Tract Dysfunction.

Roman K, Murphy SF, Done JD, McKenna KE, Schaeffer AJ, Thumbikat P.

J Urol. 2016 Aug;196(2):588-98. doi: 10.1016/j.juro.2016.01.106. Epub 2016 Feb 6.

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