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Items: 1 to 20 of 101

1.

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.

Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, Doench JG, Hahn WC, Buhrlage SJ, DeNicola GM, Kaelin WG Jr, Brugge JS.

Cell Metab. 2019 May 7;29(5):1166-1181.e6. doi: 10.1016/j.cmet.2019.01.020. Epub 2019 Feb 21.

PMID:
30799286
2.
3.

Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death.

Cortes-Wanstreet MM, Giedzinski E, Limoli CL, Luderer U.

Mutagenesis. 2009 May;24(3):211-24. doi: 10.1093/mutage/gen073. Epub 2009 Jan 18.

4.

Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells.

Song NY, Kim DH, Kim EH, Na HK, Kim NJ, Suh YG, Surh YJ.

Chem Res Toxicol. 2011 Aug 15;24(8):1231-41. doi: 10.1021/tx200090n. Epub 2011 Jul 25.

PMID:
21728338
5.

Cellular mechanisms of resistance to chronic oxidative stress.

Sagara Y, Dargusch R, Chambers D, Davis J, Schubert D, Maher P.

Free Radic Biol Med. 1998 Jun;24(9):1375-89.

PMID:
9641255
6.

TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms.

Franklin CC, Rosenfeld-Franklin ME, White C, Kavanagh TJ, Fausto N.

FASEB J. 2003 Aug;17(11):1535-7. Epub 2003 Jun 17.

PMID:
12824300
7.

MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.

Anderton B, Camarda R, Balakrishnan S, Balakrishnan A, Kohnz RA, Lim L, Evason KJ, Momcilovic O, Kruttwig K, Huang Q, Xu G, Nomura DK, Goga A.

EMBO Rep. 2017 Apr;18(4):569-585. doi: 10.15252/embr.201643068. Epub 2017 Feb 20.

8.

Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.

Zanotto-Filho A, Masamsetti VP, Loranc E, Tonapi SS, Gorthi A, Bernard X, Gonçalves RM, Moreira JC, Chen Y, Bishop AJ.

Mol Cancer Ther. 2016 Dec;15(12):3000-3014. Epub 2016 Sep 16.

9.
10.

Cigarette smoke-induced differential regulation of glutathione metabolism in bronchial epithelial cells is balanced by an antioxidant tetrapeptide UPF1.

Altraja S, Mahlapuu R, Soomets U, Altraja A.

Exp Toxicol Pathol. 2013 Sep;65(6):711-7. doi: 10.1016/j.etp.2012.09.005. Epub 2012 Oct 11.

PMID:
23062287
11.

MicroRNA-144 modulates oxidative stress tolerance in SH-SY5Y cells by regulating nuclear factor erythroid 2-related factor 2-glutathione axis.

Zhou C, Zhao L, Zheng J, Wang K, Deng H, Liu P, Chen L, Mu H.

Neurosci Lett. 2017 Aug 10;655:21-27. doi: 10.1016/j.neulet.2017.06.045. Epub 2017 Jun 27.

PMID:
28663050
12.

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response.

Meijering RA, Wiersma M, van Marion DM, Zhang D, Hoogstra-Berends F, Dijkhuis AJ, Schmidt M, Wieland T, Kampinga HH, Henning RH, Brundel BJ.

PLoS One. 2015 Jul 20;10(7):e0133553. doi: 10.1371/journal.pone.0133553. eCollection 2015.

13.

Aging impairs the expression of the catalytic subunit of glutamate cysteine ligase in soleus muscle under stress.

Chen CN, Brown-Borg HM, Rakoczy SG, Ferrington DA, Thompson LV.

J Gerontol A Biol Sci Med Sci. 2010 Feb;65(2):129-37. doi: 10.1093/gerona/glp194. Epub 2009 Dec 16.

14.

Antioxidant Effect of Barley Sprout Extract via Enhancement of Nuclear Factor-Erythroid 2 Related Factor 2 Activity and Glutathione Synthesis.

Lee YH, Kim SH, Lee S, Kim KM, Jung JC, Son TG, Ki SH, Seo WD, Kwak JH, Hong JT, Jung YS.

Nutrients. 2017 Nov 16;9(11). pii: E1252. doi: 10.3390/nu9111252.

16.

α-Lipoic acid protects against the oxidative stress and cytotoxicity induced by cadmium in HepG2 cells through regenerating glutathione regulated by glutamate-cysteine ligase.

Xu Y, Zhou X, Shi C, Wang J, Wu Z.

Toxicol Mech Methods. 2015;25(8):596-603. doi: 10.3109/15376516.2015.1044150. Epub 2015 Sep 12.

PMID:
26365678
17.
18.
19.

Glutathione synthesis.

Lu SC.

Biochim Biophys Acta. 2013 May;1830(5):3143-53. doi: 10.1016/j.bbagen.2012.09.008. Epub 2012 Sep 17. Review.

20.

Dual Roles of Glutathione in Ecdysone Biosynthesis and Antioxidant Function During Larval Development in Drosophila.

Enya S, Yamamoto C, Mizuno H, Esaki T, Lin HK, Iga M, Morohashi K, Hirano Y, Kataoka H, Masujima T, Shimada-Niwa Y, Niwa R.

Genetics. 2017 Dec;207(4):1519-1532. doi: 10.1534/genetics.117.300391. Epub 2017 Oct 11.

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