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Items: 1 to 20 of 105

1.

Targeting cholesterol metabolism in glioblastoma: a new therapeutic approach in cancer therapy.

Pirmoradi L, Seyfizadeh N, Ghavami S, Zeki AA, Shojaei S.

J Investig Med. 2019 Apr;67(4):715-719. doi: 10.1136/jim-2018-000962. Epub 2019 Feb 14.

PMID:
30765502
2.

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.

Guo D, Reinitz F, Youssef M, Hong C, Nathanson D, Akhavan D, Kuga D, Amzajerdi AN, Soto H, Zhu S, Babic I, Tanaka K, Dang J, Iwanami A, Gini B, Dejesus J, Lisiero DD, Huang TT, Prins RM, Wen PY, Robins HI, Prados MD, Deangelis LM, Mellinghoff IK, Mehta MP, James CD, Chakravarti A, Cloughesy TF, Tontonoz P, Mischel PS.

Cancer Discov. 2011 Oct;1(5):442-56. doi: 10.1158/2159-8290.CD-11-0102. Epub 2011 Sep 15. Erratum in: Cancer Discov. 2012 Feb;2(2):290-1.

3.

Intracellular cholesterol level regulates sensitivity of glioblastoma cells against temozolomide-induced cell death by modulation of caspase-8 activation via death receptor 5-accumulation and activation in the plasma membrane lipid raft.

Yamamoto Y, Tomiyama A, Sasaki N, Yamaguchi H, Shirakihara T, Nakashima K, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Ichimura K, Sakai R, Namba H, Mori K.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1292-1299. doi: 10.1016/j.bbrc.2017.11.113. Epub 2017 Nov 21.

PMID:
29162448
4.

Bis(monoacylglycero)phosphate accumulation in macrophages induces intracellular cholesterol redistribution, attenuates liver-X receptor/ATP-Binding cassette transporter A1/ATP-binding cassette transporter G1 pathway, and impairs cholesterol efflux.

Luquain-Costaz C, Lefai E, Arnal-Levron M, Markina D, Sakaï S, Euthine V, Makino A, Guichardant M, Yamashita S, Kobayashi T, Lagarde M, Moulin P, Delton-Vandenbroucke I.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1803-11. doi: 10.1161/ATVBAHA.113.301857. Epub 2013 Jun 20.

5.

Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death.

Yamamoto Y, Sasaki N, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Ichimura K, Namba H, Mori K, Tomiyama A.

Neurol Med Chir (Tokyo). 2018 Jul 15;58(7):296-302. doi: 10.2176/nmc.ra.2018-0040. Epub 2018 Jun 13. Review.

6.

Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice.

Kruit JK, Kremer PH, Dai L, Tang R, Ruddle P, de Haan W, Brunham LR, Verchere CB, Hayden MR.

Diabetologia. 2010 Jun;53(6):1110-9. doi: 10.1007/s00125-010-1691-2. Epub 2010 Mar 13.

PMID:
20229095
7.

24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.

Abildayeva K, Jansen PJ, Hirsch-Reinshagen V, Bloks VW, Bakker AH, Ramaekers FC, de Vente J, Groen AK, Wellington CL, Kuipers F, Mulder M.

J Biol Chem. 2006 May 5;281(18):12799-808. Epub 2006 Mar 8.

8.

Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes.

Maric J, Kiss RS, Franklin V, Marcel YL.

J Biol Chem. 2005 Dec 2;280(48):39942-9. Epub 2005 Oct 4.

9.

Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic Swine.

Yin K, You Y, Swier V, Tang L, Radwan MM, Pandya AN, Agrawal DK.

Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2432-42. doi: 10.1161/ATVBAHA.115.306132. Epub 2015 Sep 17.

10.

Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.

Bocchetta S, Maillard P, Yamamoto M, Gondeau C, Douam F, Lebreton S, Lagaye S, Pol S, Helle F, Plengpanich W, Guérin M, Bourgine M, Michel ML, Lavillette D, Roingeard P, le Goff W, Budkowska A.

PLoS One. 2014 Mar 19;9(3):e92140. doi: 10.1371/journal.pone.0092140. eCollection 2014.

11.

MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor.

de Aguiar Vallim TQ, Tarling EJ, Kim T, Civelek M, Baldán Á, Esau C, Edwards PA.

Circ Res. 2013 Jun 7;112(12):1602-12. doi: 10.1161/CIRCRESAHA.112.300648. Epub 2013 Mar 21.

12.

Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.

Argmann CA, Edwards JY, Sawyez CG, O'Neil CH, Hegele RA, Pickering JG, Huff MW.

J Biol Chem. 2005 Jun 10;280(23):22212-21. Epub 2005 Apr 6.

13.

Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner.

Jiang T, Ren K, Chen Q, Li H, Yao R, Hu H, Lv YC, Zhao GJ.

Cell Physiol Biochem. 2017;43(4):1703-1717. doi: 10.1159/000484031. Epub 2017 Oct 18.

14.

ATP-binding cassette transporters A1 and G1, HDL metabolism, cholesterol efflux, and inflammation: important targets for the treatment of atherosclerosis.

Ye D, Lammers B, Zhao Y, Meurs I, Van Berkel TJ, Van Eck M.

Curr Drug Targets. 2011 May;12(5):647-60. Review.

PMID:
21039336
15.

Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein.

Favari E, Lee M, Calabresi L, Franceschini G, Zimetti F, Bernini F, Kovanen PT.

J Biol Chem. 2004 Mar 12;279(11):9930-6. Epub 2003 Dec 29.

16.

Pitavastatin effect on ATP binding cassette A1-mediated lipid efflux from macrophages: evidence for liver X receptor (LXR)-dependent and LXR-independent mechanisms of activation by cAMP.

Zanotti I, Potì F, Favari E, Steffensen KR, Gustafsson JA, Bernini F.

J Pharmacol Exp Ther. 2006 Apr;317(1):395-401. Epub 2006 Jan 13.

PMID:
16415093
17.

Genetic deletion of low density lipoprotein receptor impairs sterol-induced mouse macrophage ABCA1 expression. A new SREBP1-dependent mechanism.

Zhou X, He W, Huang Z, Gotto AM Jr, Hajjar DP, Han J.

J Biol Chem. 2008 Jan 25;283(4):2129-38. Epub 2007 Nov 20.

19.

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.

Wang N, Yvan-Charvet L, Lütjohann D, Mulder M, Vanmierlo T, Kim TW, Tall AR.

FASEB J. 2008 Apr;22(4):1073-82. Epub 2007 Nov 26.

PMID:
18039927
20.

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1.

Ramirez CM, Dávalos A, Goedeke L, Salerno AG, Warrier N, Cirera-Salinas D, Suárez Y, Fernández-Hernando C.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2707-14. doi: 10.1161/ATVBAHA.111.232066.

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