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Items: 1 to 20 of 96

1.

Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.

Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM.

Nat Commun. 2019 Feb 8;10(1):660. doi: 10.1038/s41467-019-08581-8.

2.

Epithelial NEMO links innate immunity to chronic intestinal inflammation.

Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M.

Nature. 2007 Mar 29;446(7135):557-61. Epub 2007 Mar 14.

3.

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis.

Jie Z, Yang JY, Gu M, Wang H, Xie X, Li Y, Liu T, Zhu L, Shi J, Zhang L, Zhou X, Joo D, Brightbill HD, Cong Y, Lin D, Cheng X, Sun SC.

Nat Immunol. 2018 Nov;19(11):1224-1235. doi: 10.1038/s41590-018-0206-z. Epub 2018 Sep 24.

4.

Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations.

Bhattacharyya S, Borthakur A, Dudeja PK, Tobacman JK.

Exp Cell Res. 2010 Nov 15;316(19):3317-27. doi: 10.1016/j.yexcr.2010.05.004. Epub 2010 May 11.

5.

Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent.

Borthakur A, Bhattacharyya S, Alrefai WA, Tobacman JK, Ramaswamy K, Dudeja PK.

Inflamm Bowel Dis. 2010 Apr;16(4):593-603. doi: 10.1002/ibd.21092.

6.

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation.

Razani B, Zarnegar B, Ytterberg AJ, Shiba T, Dempsey PW, Ware CF, Loo JA, Cheng G.

Sci Signal. 2010 May 25;3(123):ra41. doi: 10.1126/scisignal.2000778.

7.

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernández-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M.

Nature. 2011 Jul 31;477(7364):330-4. doi: 10.1038/nature10273.

PMID:
21804564
8.

Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action.

Yousef M, Pichyangkura R, Soodvilai S, Chatsudthipong V, Muanprasat C.

Pharmacol Res. 2012 Jul;66(1):66-79. doi: 10.1016/j.phrs.2012.03.013. Epub 2012 Mar 28.

PMID:
22475725
9.

The effect of intestinal alkaline phosphatase on intestinal epithelial cells, macrophages and chronic colitis in mice.

Lee C, Chun J, Hwang SW, Kang SJ, Im JP, Kim JS.

Life Sci. 2014 Apr 1;100(2):118-24. doi: 10.1016/j.lfs.2014.02.003. Epub 2014 Feb 16.

PMID:
24548630
10.

Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria.

Shang L, Fukata M, Thirunarayanan N, Martin AP, Arnaboldi P, Maussang D, Berin C, Unkeless JC, Mayer L, Abreu MT, Lira SA.

Gastroenterology. 2008 Aug;135(2):529-38. doi: 10.1053/j.gastro.2008.04.020. Epub 2008 Apr 22.

11.

Card9 mediates intestinal epithelial cell restitution, T-helper 17 responses, and control of bacterial infection in mice.

Sokol H, Conway KL, Zhang M, Choi M, Morin B, Cao Z, Villablanca EJ, Li C, Wijmenga C, Yun SH, Shi HN, Xavier RJ.

Gastroenterology. 2013 Sep;145(3):591-601.e3. doi: 10.1053/j.gastro.2013.05.047. Epub 2013 May 31.

12.

B-cell CLL/lymphoma 10 (BCL10) is required for NF-kappaB production by both canonical and noncanonical pathways and for NF-kappaB-inducing kinase (NIK) phosphorylation.

Bhattacharyya S, Borthakur A, Tyagi S, Gill R, Chen ML, Dudeja PK, Tobacman JK.

J Biol Chem. 2010 Jan 1;285(1):522-30. doi: 10.1074/jbc.M109.050815. Epub 2009 Nov 6.

14.

Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB.

Demchenko YN, Brents LA, Li Z, Bergsagel LP, McGee LR, Kuehl MW.

Oncotarget. 2014 Jun 30;5(12):4554-66.

15.

TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway.

Al-Sadi R, Guo S, Ye D, Rawat M, Ma TY.

Am J Pathol. 2016 May;186(5):1151-65. doi: 10.1016/j.ajpath.2015.12.016. Epub 2016 Mar 4.

16.

Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses.

Li Y, Wang H, Zhou X, Xie X, Chen X, Jie Z, Zou Q, Hu H, Zhu L, Cheng X, Brightbill HD, Wu LC, Wang L, Sun SC.

Sci Rep. 2016 Feb 25;6:22115. doi: 10.1038/srep22115.

17.

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

Powell N, Lo JW, Biancheri P, Vossenkämper A, Pantazi E, Walker AW, Stolarczyk E, Ammoscato F, Goldberg R, Scott P, Canavan JB, Perucha E, Garrido-Mesa N, Irving PM, Sanderson JD, Hayee B, Howard JK, Parkhill J, MacDonald TT, Lord GM.

Gastroenterology. 2015 Aug;149(2):456-67.e15. doi: 10.1053/j.gastro.2015.04.017. Epub 2015 Apr 25.

18.

Vitamin A deficiency suppresses fish immune function with differences in different intestinal segments: the role of transcriptional factor NF-κB and p38 mitogen-activated protein kinase signalling pathways.

Zhang L, Feng L, Jiang WD, Liu Y, Wu P, Kuang SY, Tang L, Tang WN, Zhang YA, Zhou XQ.

Br J Nutr. 2017 Jan;117(1):67-82. doi: 10.1017/S0007114516003342. Epub 2017 Jan 18.

PMID:
28098047
20.

NFκB-inducing kinase inhibits NFκB activity specifically in neurons of the CNS.

Mao X, Phanavanh B, Hamdan H, Moerman-Herzog AM, Barger SW.

J Neurochem. 2016 Apr;137(2):154-63. doi: 10.1111/jnc.13526. Epub 2016 Mar 15.

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