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Items: 1 to 20 of 110

1.

Kinetic characterization of Cas9 enzymes.

Liu MS, Gong S, Yu HH, Taylor DW, Johnson KA.

Methods Enzymol. 2019;616:289-311. doi: 10.1016/bs.mie.2018.10.022. Epub 2019 Jan 14.

PMID:
30691648
2.

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E.

Science. 2012 Aug 17;337(6096):816-21. doi: 10.1126/science.1225829. Epub 2012 Jun 28.

3.

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.

Fonfara I, Richter H, Bratovič M, Le Rhun A, Charpentier E.

Nature. 2016 Apr 28;532(7600):517-21. doi: 10.1038/nature17945. Epub 2016 Apr 20.

PMID:
27096362
4.

CRISPR-Cas9 Structures and Mechanisms.

Jiang F, Doudna JA.

Annu Rev Biophys. 2017 May 22;46:505-529. doi: 10.1146/annurev-biophys-062215-010822. Epub 2017 Mar 30. Review.

PMID:
28375731
5.

Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9.

Raper AT, Stephenson AA, Suo Z.

J Am Chem Soc. 2018 Feb 28;140(8):2971-2984. doi: 10.1021/jacs.7b13047. Epub 2018 Feb 19.

PMID:
29442507
6.

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus.

Karvelis T, Gasiunas G, Miksys A, Barrangou R, Horvath P, Siksnys V.

RNA Biol. 2013 May;10(5):841-51. doi: 10.4161/rna.24203. Epub 2013 Mar 27.

7.

The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems.

Chylinski K, Le Rhun A, Charpentier E.

RNA Biol. 2013 May;10(5):726-37. doi: 10.4161/rna.24321. Epub 2013 Apr 5.

8.

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.

Gasiunas G, Barrangou R, Horvath P, Siksnys V.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2579-86. Epub 2012 Sep 4.

9.

Efficient Multiple Genome Modifications Induced by the crRNAs, tracrRNA and Cas9 Protein Complex in Zebrafish.

Kotani H, Taimatsu K, Ohga R, Ota S, Kawahara A.

PLoS One. 2015 May 26;10(5):e0128319. doi: 10.1371/journal.pone.0128319. eCollection 2015.

10.

Synthetic CRISPR RNA-Cas9-guided genome editing in human cells.

Rahdar M, McMahon MA, Prakash TP, Swayze EE, Bennett CF, Cleveland DW.

Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):E7110-7. doi: 10.1073/pnas.1520883112. Epub 2015 Nov 16.

11.

Cut site selection by the two nuclease domains of the Cas9 RNA-guided endonuclease.

Chen H, Choi J, Bailey S.

J Biol Chem. 2014 May 9;289(19):13284-94. doi: 10.1074/jbc.M113.539726. Epub 2014 Mar 14.

12.

CRISPR/Cas9 for genome editing: progress, implications and challenges.

Zhang F, Wen Y, Guo X.

Hum Mol Genet. 2014 Sep 15;23(R1):R40-6. doi: 10.1093/hmg/ddu125. Epub 2014 Mar 20. Review.

PMID:
24651067
13.

Optimized guide RNA structure for genome editing via Cas9.

Xu J, Lian W, Jia Y, Li L, Huang Z.

Oncotarget. 2017 Oct 7;8(55):94166-94171. doi: 10.18632/oncotarget.21607. eCollection 2017 Nov 7.

14.

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity.

Charpentier E, Richter H, van der Oost J, White MF.

FEMS Microbiol Rev. 2015 May;39(3):428-41. doi: 10.1093/femsre/fuv023. Epub 2015 May 19. Review.

15.

Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment.

Kennedy EM, Cullen BR.

Virology. 2015 May;479-480:213-20. doi: 10.1016/j.virol.2015.02.024. Epub 2015 Mar 7. Review.

16.

DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity.

Gong S, Yu HH, Johnson KA, Taylor DW.

Cell Rep. 2018 Jan 9;22(2):359-371. doi: 10.1016/j.celrep.2017.12.041.

17.

In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target.

Anders C, Niewoehner O, Jinek M.

Methods Enzymol. 2015;558:515-537. doi: 10.1016/bs.mie.2015.02.008. Epub 2015 Mar 12.

18.

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.

Lee CM, Cradick TJ, Bao G.

Mol Ther. 2016 Mar;24(3):645-54. doi: 10.1038/mt.2016.8. Epub 2016 Jan 19.

19.

Chimeric Guides Probe and Enhance Cas9 Biochemical Activity.

Kartje ZJ, Barkau CL, Rohilla KJ, Ageely EA, Gagnon KT.

Biochemistry. 2018 May 29;57(21):3027-3031. doi: 10.1021/acs.biochem.8b00107. Epub 2018 May 14.

PMID:
29746102
20.

New vectors for simple and streamlined CRISPR-Cas9 genome editing in Saccharomyces cerevisiae.

Laughery MF, Hunter T, Brown A, Hoopes J, Ostbye T, Shumaker T, Wyrick JJ.

Yeast. 2015 Dec;32(12):711-20. doi: 10.1002/yea.3098. Epub 2015 Sep 21.

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