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Items: 1 to 20 of 101

1.

Deimmunizing substitutions in Pseudomonas exotoxin domain III perturb antigen processing without eliminating T-cell epitopes.

Moss DL, Park HW, Mettu RR, Landry SJ.

J Biol Chem. 2019 Mar 22;294(12):4667-4681. doi: 10.1074/jbc.RA118.006704. Epub 2019 Jan 25.

PMID:
30683694
2.

Comprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein.

Li T, Steede NK, Nguyen HN, Freytag LC, McLachlan JB, Mettu RR, Robinson JE, Landry SJ.

J Virol. 2014 Sep 1;88(17):9605-15. doi: 10.1128/JVI.00789-14. Epub 2014 Jun 11.

3.

CD4+ T-cell epitope prediction using antigen processing constraints.

Mettu RR, Charles T, Landry SJ.

J Immunol Methods. 2016 May;432:72-81. doi: 10.1016/j.jim.2016.02.013. Epub 2016 Feb 15.

4.

Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity.

Kaumaya PT, Kobs-Conrad S, Seo YH, Lee H, VanBuskirk AM, Feng N, Sheridan JF, Stevens V.

J Mol Recognit. 1993 Jun;6(2):81-94.

PMID:
7508238
5.

mAb against hen egg-white lysozyme regulate its presentation to CD4(+) T cells.

Guermonprez P, Lo-Man R, Sedlik C, Rojas MJ, Poljak RJ, Leclerc C.

Int Immunol. 1999 Nov;11(11):1863-72.

PMID:
10545490
6.

Specificities of human CD4+ T cell responses to an inactivated flavivirus vaccine and infection: correlation with structure and epitope prediction.

Schwaiger J, Aberle JH, Stiasny K, Knapp B, Schreiner W, Fae I, Fischer G, Scheinost O, Chmelik V, Heinz FX.

J Virol. 2014 Jul;88(14):7828-42. doi: 10.1128/JVI.00196-14. Epub 2014 Apr 30.

8.

Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin.

Sarnovsky R, Tendler T, Makowski M, Kiley M, Antignani A, Traini R, Zhang J, Hassan R, FitzGerald DJ.

Cancer Immunol Immunother. 2010 May;59(5):737-46. doi: 10.1007/s00262-009-0794-4. Epub 2009 Nov 29.

PMID:
20091030
9.
10.

Analyzing the effect of peptide-HLA-binding ability on the immunogenicity of potential CD8+ and CD4+ T cell epitopes in a large dataset.

Wang S, Li J, Chen X, Wang L, Liu W, Wu Y.

Immunol Res. 2016 Aug;64(4):908-18. doi: 10.1007/s12026-016-8795-9.

PMID:
27094547
11.

Sequential proteolytic processing of the capsular Caf1 antigen of Yersinia pestis for major histocompatibility complex class II-restricted presentation to T lymphocytes.

Musson JA, Morton M, Walker N, Harper HM, McNeill HV, Williamson ED, Robinson JH.

J Biol Chem. 2006 Sep 8;281(36):26129-35. Epub 2006 Jul 13.

12.

Identification of HLA class II H5N1 hemagglutinin epitopes following subvirion influenza A (H5N1) vaccination.

Zinckgraf JW, Sposato M, Zielinski V, Powell D, Treanor JJ, von Hofe E.

Vaccine. 2009 Aug 27;27(39):5393-401. doi: 10.1016/j.vaccine.2009.06.081. Epub 2009 Jul 9.

PMID:
19596415
13.

Strategies to enhance immunogenicity of cDNA vaccine encoded antigens by modulation of antigen processing.

Platteel ACM, Marit de Groot A, Keller C, Andersen P, Ovaa H, Kloetzel PM, Mishto M, Sijts AJAM.

Vaccine. 2016 Sep 30;34(42):5132-5140. doi: 10.1016/j.vaccine.2016.08.039. Epub 2016 Sep 1.

PMID:
27593157
14.

Determination of a Predictive Cleavage Motif for Eluted Major Histocompatibility Complex Class II Ligands.

Paul S, Karosiene E, Dhanda SK, Jurtz V, Edwards L, Nielsen M, Sette A, Peters B.

Front Immunol. 2018 Aug 6;9:1795. doi: 10.3389/fimmu.2018.01795. eCollection 2018.

15.

Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition.

Schneidman-Duhovny D, Khuri N, Dong GQ, Winter MB, Shifrut E, Friedman N, Craik CS, Pratt KP, Paz P, Aswad F, Sali A.

PLoS One. 2018 Nov 6;13(11):e0206654. doi: 10.1371/journal.pone.0206654. eCollection 2018.

17.

Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38.

Mazor R, Kaplan G, Park D, Jang Y, Lee F, Kreitman R, Pastan I.

Cell Immunol. 2017 Mar;313:59-66. doi: 10.1016/j.cellimm.2017.01.003. Epub 2017 Jan 5.

18.

Fusion protein vaccine by domains of bacterial exotoxin linked with a tumor antigen generates potent immunologic responses and antitumor effects.

Liao CW, Chen CA, Lee CN, Su YN, Chang MC, Syu MH, Hsieh CY, Cheng WF.

Cancer Res. 2005 Oct 1;65(19):9089-98.

19.

CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses.

Rasmussen IB, Oynebråten I, Høydahl LS, Flobakk M, Lunde E, Michaelsen TE, Bogen B, Sandlie I.

Protein Eng Des Sel. 2012 Mar;25(3):89-96. doi: 10.1093/protein/gzr063. Epub 2012 Jan 10.

PMID:
22233931
20.

Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background.

Lo-Man R, Martineau P, Hofnung M, Leclerc C.

Cell Immunol. 1996 Sep 15;172(2):180-91.

PMID:
8964079

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