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Items: 1 to 20 of 93

1.

Targeting anticancer drug-induced senescence in glioblastoma therapy.

Tomicic MT, Christmann M.

Oncotarget. 2018 Dec 25;9(101):37466-37467. doi: 10.18632/oncotarget.26502. eCollection 2018 Dec 25. No abstract available.

2.

Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR-CHK1, p21, and NF-κB.

Aasland D, Götzinger L, Hauck L, Berte N, Meyer J, Effenberger M, Schneider S, Reuber EE, Roos WP, Tomicic MT, Kaina B, Christmann M.

Cancer Res. 2019 Jan 1;79(1):99-113. doi: 10.1158/0008-5472.CAN-18-1733. Epub 2018 Oct 25.

PMID:
30361254
3.

NETRIN-4 protects glioblastoma cells FROM temozolomide induced senescence.

Li L, Hu Y, Ylivinkka I, Li H, Chen P, Keski-Oja J, Hyytiäinen M.

PLoS One. 2013 Nov 12;8(11):e80363. doi: 10.1371/journal.pone.0080363. eCollection 2013.

4.

Carnitine-induced senescence in glioblastoma cells.

Yamada S, Matsuda R, Nishimura F, Nakagawa I, Motoyama Y, Park YS, Nakamura M, Nakase H, Ouji Y, Yoshikawa M.

Exp Ther Med. 2012 Jul;4(1):21-25. Epub 2012 Apr 23.

5.

Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.

Filippi-Chiela EC, Thomé MP, Bueno e Silva MM, Pelegrini AL, Ledur PF, Garicochea B, Zamin LL, Lenz G.

BMC Cancer. 2013 Mar 22;13:147. doi: 10.1186/1471-2407-13-147.

6.

Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.

Berte N, Lokan S, Eich M, Kim E, Kaina B.

Oncotarget. 2016 Oct 11;7(41):67235-67250. doi: 10.18632/oncotarget.11972.

7.

An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.

Pawlowska E, Szczepanska J, Szatkowska M, Blasiak J.

Int J Mol Sci. 2018 Mar 17;19(3). pii: E889. doi: 10.3390/ijms19030889. Review.

8.

Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway.

Liu Q, Xu X, Zhao M, Wei Z, Li X, Zhang X, Liu Z, Gong Y, Shao C.

Mol Cancer Ther. 2015 Feb;14(2):355-63. doi: 10.1158/1535-7163.MCT-14-0634. Epub 2014 Dec 12.

9.

c-Myc-miR-29c-REV3L signalling pathway drives the acquisition of temozolomide resistance in glioblastoma.

Luo H, Chen Z, Wang S, Zhang R, Qiu W, Zhao L, Peng C, Xu R, Chen W, Wang HW, Chen Y, Yang J, Zhang X, Zhang S, Chen D, Wu W, Zhao C, Cheng G, Jiang T, Lu D, You Y, Liu N, Wang H.

Brain. 2015 Dec;138(Pt 12):3654-72. doi: 10.1093/brain/awv287. Epub 2015 Oct 8.

PMID:
26450587
10.

Novel nanohydrogel of hyaluronic acid loaded with quercetin alone and in combination with temozolomide as new therapeutic tool, CD44 targeted based, of glioblastoma multiforme.

Barbarisi M, Iaffaioli RV, Armenia E, Schiavo L, De Sena G, Tafuto S, Barbarisi A, Quagliariello V.

J Cell Physiol. 2018 Oct;233(10):6550-6564. doi: 10.1002/jcp.26238. Epub 2018 May 8.

PMID:
29030990
11.
12.

Clinical strategies and animal models for developing senolytic agents.

Kirkland JL, Tchkonia T.

Exp Gerontol. 2015 Aug;68:19-25. doi: 10.1016/j.exger.2014.10.012. Epub 2014 Oct 28.

13.

Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals.

Malavolta M, Pierpaoli E, Giacconi R, Costarelli L, Piacenza F, Basso A, Cardelli M, Provinciali M.

Curr Drug Targets. 2016;17(4):447-59. Review.

PMID:
26343116
14.

The regrowth kinetic of the surviving population is independent of acute and chronic responses to temozolomide in glioblastoma cell lines.

Silva AO, Dalsin E, Onzi GR, Filippi-Chiela EC, Lenz G.

Exp Cell Res. 2016 Nov 1;348(2):177-183. doi: 10.1016/j.yexcr.2016.09.014. Epub 2016 Sep 23.

PMID:
27669643
15.
16.

Contribution of ATM and ATR to the resistance of glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide.

Eich M, Roos WP, Nikolova T, Kaina B.

Mol Cancer Ther. 2013 Nov;12(11):2529-40. doi: 10.1158/1535-7163.MCT-13-0136. Epub 2013 Aug 19.

17.

Azithromycin and Roxithromycin define a new family of "senolytic" drugs that target senescent human fibroblasts.

Ozsvari B, Nuttall JR, Sotgia F, Lisanti MP.

Aging (Albany NY). 2018 Nov 14;10(11):3294-3307. doi: 10.18632/aging.101633.

18.

Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.

Chen TC, Wang W, Golden EB, Thomas S, Sivakumar W, Hofman FM, Louie SG, Schönthal AH.

Cancer Lett. 2011 Mar 28;302(2):100-8. doi: 10.1016/j.canlet.2010.11.008. Epub 2011 Jan 22.

PMID:
21257259
19.

Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death.

Yamamoto Y, Sasaki N, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Ichimura K, Namba H, Mori K, Tomiyama A.

Neurol Med Chir (Tokyo). 2018 Jul 15;58(7):296-302. doi: 10.2176/nmc.ra.2018-0040. Epub 2018 Jun 13. Review.

20.

Cellular senescence in the aging and diseased kidney.

Valentijn FA, Falke LL, Nguyen TQ, Goldschmeding R.

J Cell Commun Signal. 2018 Mar;12(1):69-82. doi: 10.1007/s12079-017-0434-2. Epub 2017 Dec 19. Review.

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