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Items: 1 to 20 of 90

1.

Depression Stresses the Immune Response and Promotes Prostate Cancer Growth.

Mohammadpour H, Bucsek MJ, Hylander BL, Repasky EA.

Clin Cancer Res. 2019 Jan 22. doi: 10.1158/1078-0432.CCR-18-3980. [Epub ahead of print]

PMID:
30670491
2.

Depression-Induced Neuropeptide Y Secretion Promotes Prostate Cancer Growth by Recruiting Myeloid Cells.

Cheng Y, Tang XY, Li YX, Zhao DD, Cao QH, Wu HX, Yang HB, Hao K, Yang Y.

Clin Cancer Res. 2018 Nov 30. doi: 10.1158/1078-0432.CCR-18-2912. [Epub ahead of print]

PMID:
30504424
3.

TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients.

Hossain DM, Pal SK, Moreira D, Duttagupta P, Zhang Q, Won H, Jones J, D'Apuzzo M, Forman S, Kortylewski M.

Clin Cancer Res. 2015 Aug 15;21(16):3771-82. doi: 10.1158/1078-0432.CCR-14-3145. Epub 2015 May 12.

4.

Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases.

Thorn M, Guha P, Cunetta M, Espat NJ, Miller G, Junghans RP, Katz SC.

Cancer Gene Ther. 2016 Jun;23(6):188-98. doi: 10.1038/cgt.2016.19. Epub 2016 May 20.

PMID:
27199222
5.

Curcumin induces the differentiation of myeloid-derived suppressor cells and inhibits their interaction with cancer cells and related tumor growth.

Tu SP, Jin H, Shi JD, Zhu LM, Suo Y, Lu G, Liu A, Wang TC, Yang CS.

Cancer Prev Res (Phila). 2012 Feb;5(2):205-15. doi: 10.1158/1940-6207.CAPR-11-0247. Epub 2011 Oct 26.

6.

Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells.

Deng Y, Cheng J, Fu B, Liu W, Chen G, Zhang Q, Yang Y.

Oncogene. 2017 Feb 23;36(8):1090-1101. doi: 10.1038/onc.2016.273. Epub 2016 Sep 5.

PMID:
27593937
7.

Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression.

Pinton L, Solito S, Damuzzo V, Francescato S, Pozzuoli A, Berizzi A, Mocellin S, Rossi CR, Bronte V, Mandruzzato S.

Oncotarget. 2016 Jan 12;7(2):1168-84. doi: 10.18632/oncotarget.6662.

8.

TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs.

Won H, Moreira D, Gao C, Duttagupta P, Zhao X, Manuel E, Diamond D, Yuan YC, Liu Z, Jones J, D'Apuzzo M, Pal S, Kortylewski M.

J Leukoc Biol. 2017 Aug;102(2):423-436. doi: 10.1189/jlb.3MA1016-451RR. Epub 2017 May 22.

9.

Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies.

Shou D, Wen L, Song Z, Yin J, Sun Q, Gong W.

Oncotarget. 2016 Sep 27;7(39):64505-64511. doi: 10.18632/oncotarget.11352. Review.

10.

SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells.

Yu H, Liu Y, McFarland BC, Deshane JS, Hurst DR, Ponnazhagan S, Benveniste EN, Qin H.

Cancer Immunol Res. 2015 Jul;3(7):727-40. doi: 10.1158/2326-6066.CIR-15-0004. Epub 2015 Feb 3.

11.

High-Fat Diet-Induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling.

Hayashi T, Fujita K, Nojima S, Hayashi Y, Nakano K, Ishizuya Y, Wang C, Yamamoto Y, Kinouchi T, Matsuzaki K, Jingushi K, Kato T, Kawashima A, Nagahara A, Ujike T, Uemura M, Pena MDCR, Gordetsky JB, Morii E, Tsujikawa K, Netto GJ, Nonomura N.

Clin Cancer Res. 2018 Sep 1;24(17):4309-4318. doi: 10.1158/1078-0432.CCR-18-0106. Epub 2018 May 18.

PMID:
29776955
12.

Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression.

Garcia AJ, Ruscetti M, Arenzana TL, Tran LM, Bianci-Frias D, Sybert E, Priceman SJ, Wu L, Nelson PS, Smale ST, Wu H.

Mol Cell Biol. 2014 Jun;34(11):2017-28. doi: 10.1128/MCB.00090-14. Epub 2014 Mar 24. Erratum in: Mol Cell Biol. 2014 Sep;34(17):3354.

13.

IL-17 inhibits the accumulation of myeloid-derived suppressor cells in breast cancer via activating STAT3.

Ma M, Huang W, Kong D.

Int Immunopharmacol. 2018 Jun;59:148-156. doi: 10.1016/j.intimp.2018.04.013. Epub 2018 Apr 11.

PMID:
29655056
14.

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis.

Waight JD, Netherby C, Hensen ML, Miller A, Hu Q, Liu S, Bogner PN, Farren MR, Lee KP, Liu K, Abrams SI.

J Clin Invest. 2013 Oct;123(10):4464-78. doi: 10.1172/JCI68189. Epub 2013 Sep 16.

15.

Breaking bad habits: Targeting MDSCs to alleviate immunosuppression in prostate cancer.

Pal SK, Kortylewski M.

Oncoimmunology. 2015 Aug 24;5(2):e1078060. eCollection 2016 Feb.

16.

Effective combinatorial immunotherapy for castration-resistant prostate cancer.

Lu X, Horner JW, Paul E, Shang X, Troncoso P, Deng P, Jiang S, Chang Q, Spring DJ, Sharma P, Zebala JA, Maeda DY, Wang YA, DePinho RA.

Nature. 2017 Mar 30;543(7647):728-732. doi: 10.1038/nature21676. Epub 2017 Mar 20. Erratum in: Nature. 2017 May 3;545(7652):116.

17.

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression.

Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, Guo Z, Ramamoorthy V, Tieu TN, Heffernan T, Zhao D, Shang X, Khadka S, Hou P, Hu B, Jin EJ, Yao W, Pan X, Ding Z, Shi Y, Li L, Chang Q, Troncoso P, Logothetis CJ, McArthur MJ, Chin L, Wang YA, DePinho RA.

Cancer Discov. 2016 Jan;6(1):80-95. doi: 10.1158/2159-8290.CD-15-0224. Epub 2015 Dec 23.

18.

Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma.

Abad C, Nobuta H, Li J, Kasai A, Yong WH, Waschek JA.

J Leukoc Biol. 2014 Feb;95(2):357-67. doi: 10.1189/jlb.1012531. Epub 2013 Sep 25.

19.

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy.

Finke J, Ko J, Rini B, Rayman P, Ireland J, Cohen P.

Int Immunopharmacol. 2011 Jul;11(7):856-61. doi: 10.1016/j.intimp.2011.01.030. Epub 2011 Feb 11.

20.

Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer.

Yu J, Du W, Yan F, Wang Y, Li H, Cao S, Yu W, Shen C, Liu J, Ren X.

J Immunol. 2013 Apr 1;190(7):3783-97. doi: 10.4049/jimmunol.1201449. Epub 2013 Feb 25.

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