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Items: 1 to 20 of 105

1.

Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk.

Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY.

Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18.

PMID:
30659021
2.

Overexpression of alpha4 chain-containing laminins in human glial tumors identified by gene microarray analysis.

Ljubimova JY, Lakhter AJ, Loksh A, Yong WH, Riedinger MS, Miner JH, Sorokin LM, Ljubimov AV, Black KL.

Cancer Res. 2001 Jul 15;61(14):5601-10.

3.

Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme.

Chou ST, Patil R, Galstyan A, Gangalum PR, Cavenee WK, Furnari FB, Ljubimov VA, Chesnokova A, Kramerov AA, Ding H, Falahatian V, Mashouf L, Fox I, Black KL, Holler E, Ljubimov AV, Ljubimova JY.

J Control Release. 2016 Dec 28;244(Pt A):14-23. doi: 10.1016/j.jconrel.2016.11.001. Epub 2016 Nov 5.

4.

NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.

Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG.

Stem Cells. 2010 Jan;28(1):5-16. doi: 10.1002/stem.254.

5.

Association between laminin-8 and glial tumor grade, recurrence, and patient survival.

Ljubimova JY, Fugita M, Khazenzon NM, Das A, Pikul BB, Newman D, Sekiguchi K, Sorokin LM, Sasaki T, Black KL.

Cancer. 2004 Aug 1;101(3):604-12.

6.

Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature.

Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT.

Cancer Biol Ther. 2014 Jul;15(7):862-77. doi: 10.4161/cbt.28876. Epub 2014 Apr 22.

7.

PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment.

Cenciarelli C, Marei HE, Zonfrillo M, Pierimarchi P, Paldino E, Casalbore P, Felsani A, Vescovi AL, Maira G, Mangiola A.

Mol Cancer. 2014 Nov 8;13:247. doi: 10.1186/1476-4598-13-247.

8.

Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis.

Fujita M, Khazenzon NM, Ljubimov AV, Lee BS, Virtanen I, Holler E, Black KL, Ljubimova JY.

Angiogenesis. 2006;9(4):183-91. Epub 2006 Nov 16.

9.

NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma.

Yahyanejad S, King H, Iglesias VS, Granton PV, Barbeau LM, van Hoof SJ, Groot AJ, Habets R, Prickaerts J, Chalmers AJ, Eekers DB, Theys J, Short SC, Verhaegen F, Vooijs M.

Oncotarget. 2016 Jul 5;7(27):41251-41264. doi: 10.18632/oncotarget.9275.

10.

Resveratrol targeting of AKT and p53 in glioblastoma and glioblastoma stem-like cells to suppress growth and infiltration.

Clark PA, Bhattacharya S, Elmayan A, Darjatmoko SR, Thuro BA, Yan MB, van Ginkel PR, Polans AS, Kuo JS.

J Neurosurg. 2017 May;126(5):1448-1460. doi: 10.3171/2016.1.JNS152077. Epub 2016 Jul 15.

11.

Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition.

Ying M, Wang S, Sang Y, Sun P, Lal B, Goodwin CR, Guerrero-Cazares H, Quinones-Hinojosa A, Laterra J, Xia S.

Oncogene. 2011 Aug 4;30(31):3454-67. doi: 10.1038/onc.2011.58. Epub 2011 Mar 7.

12.

HSP47 Promotes Glioblastoma Stemlike Cell Survival by Modulating Tumor Microenvironment Extracellular Matrix through TGF-β Pathway.

Jiang X, Zhou T, Wang Z, Qi B, Xia H.

ACS Chem Neurosci. 2017 Jan 18;8(1):128-134. doi: 10.1021/acschemneuro.6b00253. Epub 2016 Oct 12.

PMID:
27696866
13.

MiR-124-5p inhibits the growth of high-grade gliomas through posttranscriptional regulation of LAMB1.

Chen Q, Lu G, Cai Y, Li Y, Xu R, Ke Y, Zhang S.

Neuro Oncol. 2014 May;16(5):637-51. doi: 10.1093/neuonc/not300. Epub 2014 Feb 3.

14.

Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness.

Ylivinkka I, Sihto H, Tynninen O, Hu Y, Laakso A, Kivisaari R, Laakkonen P, Keski-Oja J, Hyytiäinen M.

J Exp Clin Cancer Res. 2017 Jan 9;36(1):9. doi: 10.1186/s13046-016-0482-0.

15.

Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer.

Ding H, Helguera G, Rodríguez JA, Markman J, Luria-Pérez R, Gangalum P, Portilla-Arias J, Inoue S, Daniels-Wells TR, Black K, Holler E, Penichet ML, Ljubimova JY.

J Control Release. 2013 Nov 10;171(3):322-9. doi: 10.1016/j.jconrel.2013.06.001. Epub 2013 Jun 12.

16.

Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells.

Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, Hamm LL, He X, Hervey-Jumper SL, Heth JA, Muraszko KM, DiMeco F, Vescovi AL, Fan X.

Cancer Res. 2011 Sep 15;71(18):6061-72. doi: 10.1158/0008-5472.CAN-10-4269. Epub 2011 Jul 25.

17.

Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases.

Fujita M, Khazenzon NM, Bose S, Sekiguchi K, Sasaki T, Carter WG, Ljubimov AV, Black KL, Ljubimova JY.

Breast Cancer Res. 2005;7(4):R411-21. Epub 2005 Apr 6.

18.

Sox2, a stemness gene, regulates tumor-initiating and drug-resistant properties in CD133-positive glioblastoma stem cells.

Song WS, Yang YP, Huang CS, Lu KH, Liu WH, Wu WW, Lee YY, Lo WL, Lee SD, Chen YW, Huang PI, Chen MT.

J Chin Med Assoc. 2016 Oct;79(10):538-45. doi: 10.1016/j.jcma.2016.03.010. Epub 2016 Aug 13.

19.

Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.

Hu B, Nandhu MS, Sim H, Agudelo-Garcia PA, Saldivar JC, Dolan CE, Mora ME, Nuovo GJ, Cole SE, Viapiano MS.

Cancer Res. 2012 Aug 1;72(15):3873-85. doi: 10.1158/0008-5472.CAN-12-1060. Epub 2012 Jun 4.

20.

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.

Di K, Linskey ME, Bota DA.

Oncogene. 2013 Oct 17;32(42):5038-47. doi: 10.1038/onc.2012.531. Epub 2012 Nov 26.

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