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Items: 1 to 20 of 107

1.

Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer.

Shapira-Furman T, Serra R, Gorelick N, Doglioli M, Tagliaferri V, Cecia A, Peters M, Kumar A, Rottenberg Y, Langer R, Brem H, Tyler B, Domb AJ.

J Control Release. 2019 Feb 10;295:93-101. doi: 10.1016/j.jconrel.2018.12.048. Epub 2018 Dec 31.

PMID:
30605703
2.

Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme.

McGirt MJ, Than KD, Weingart JD, Chaichana KL, Attenello FJ, Olivi A, Laterra J, Kleinberg LR, Grossman SA, Brem H, Quiñones-Hinojosa A.

J Neurosurg. 2009 Mar;110(3):583-8. doi: 10.3171/2008.5.17557.

4.

First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.

Bock HC, Puchner MJ, Lohmann F, Schütze M, Koll S, Ketter R, Buchalla R, Rainov N, Kantelhardt SR, Rohde V, Giese A.

Neurosurg Rev. 2010 Oct;33(4):441-9. doi: 10.1007/s10143-010-0280-7. Epub 2010 Aug 13.

5.

Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.

Recinos VR, Tyler BM, Bekelis K, Sunshine SB, Vellimana A, Li KW, Brem H.

Neurosurgery. 2010 Mar;66(3):530-7; discussion 537. doi: 10.1227/01.NEU.0000365263.14725.39.

PMID:
20173548
6.

A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.

Pan E, Mitchell SB, Tsai JS.

J Neurooncol. 2008 Jul;88(3):353-7. doi: 10.1007/s11060-008-9576-7. Epub 2008 Apr 4.

PMID:
18389176
7.

A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.

Westphal M, Hilt DC, Bortey E, Delavault P, Olivares R, Warnke PC, Whittle IR, Jääskeläinen J, Ram Z.

Neuro Oncol. 2003 Apr;5(2):79-88.

8.

Evaluation of in vitro and in vivo antitumor activity of BCNU-loaded PLGA wafer against 9L gliosarcoma.

Lee JS, An TK, Chae GS, Jeong JK, Cho SH, Lee HB, Khang G.

Eur J Pharm Biopharm. 2005 Jan;59(1):169-75.

PMID:
15567315
9.

The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.

Garside R, Pitt M, Anderson R, Rogers G, Dyer M, Mealing S, Somerville M, Price A, Stein K.

Health Technol Assess. 2007 Nov;11(45):iii-iv, ix-221. Review.

10.

BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase II trial.

Burri SH, Prabhu RS, Sumrall AL, Brick W, Blaker BD, Heideman BE Jr, Boltes P, Kelly R, Symanowski JT, Wiggins WF, Ashby L, Norton HJ, Judy K, Asher AL.

J Neurooncol. 2015 Jun;123(2):259-66. doi: 10.1007/s11060-015-1793-2. Epub 2015 May 7.

PMID:
25947286
11.

Impact of the per-operatory application of GLIADEL wafers (BCNU, carmustine) in combination with temozolomide and radiotherapy in patients with glioblastoma multiforme: efficacy and toxicity.

Miglierini P, Bouchekoua M, Rousseau B, Hieu PD, Malhaire JP, Pradier O.

Clin Neurol Neurosurg. 2012 Nov;114(9):1222-5. doi: 10.1016/j.clineuro.2012.02.056. Epub 2012 Mar 31.

PMID:
22464950
12.

MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers.

Gutenberg A, Bock HC, Brück W, Doerner L, Mehdorn HM, Roggendorf W, Westphal M, Felsberg J, Reifenberger G, Giese A.

Br J Neurosurg. 2013 Dec;27(6):772-8. doi: 10.3109/02688697.2013.791664. Epub 2013 May 11.

PMID:
23662801
13.
14.

Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.

Westphal M, Ram Z, Riddle V, Hilt D, Bortey E; Executive Committee of the Gliadel Study Group.

Acta Neurochir (Wien). 2006 Mar;148(3):269-75; discussion 275. Epub 2006 Feb 17.

PMID:
16482400
15.

Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.

Affronti ML, Heery CR, Herndon JE 2nd, Rich JN, Reardon DA, Desjardins A, Vredenburgh JJ, Friedman AH, Bigner DD, Friedman HS.

Cancer. 2009 Aug 1;115(15):3501-11. doi: 10.1002/cncr.24398.

16.

The role of Gliadel wafers in the treatment of newly diagnosed GBM: a meta-analysis.

Xing WK, Shao C, Qi ZY, Yang C, Wang Z.

Drug Des Devel Ther. 2015 Jun 29;9:3341-8. doi: 10.2147/DDDT.S85943. eCollection 2015. Review.

17.

Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience.

Attenello FJ, Mukherjee D, Datoo G, McGirt MJ, Bohan E, Weingart JD, Olivi A, Quinones-Hinojosa A, Brem H.

Ann Surg Oncol. 2008 Oct;15(10):2887-93. doi: 10.1245/s10434-008-0048-2. Epub 2008 Jul 18.

PMID:
18636295
18.

Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.

Scott AW, Tyler BM, Masi BC, Upadhyay UM, Patta YR, Grossman R, Basaldella L, Langer RS, Brem H, Cima MJ.

Biomaterials. 2011 Apr;32(10):2532-9. doi: 10.1016/j.biomaterials.2010.12.020. Epub 2011 Jan 8.

PMID:
21220172
19.

Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.

Wicks RT, Azadi J, Mangraviti A, Zhang I, Hwang L, Joshi A, Bow H, Hutt-Cabezas M, Martin KL, Rudek MA, Zhao M, Brem H, Tyler BM.

Neuro Oncol. 2015 Jan;17(1):70-80. doi: 10.1093/neuonc/nou143. Epub 2014 Jul 22.

20.

Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma.

Rhines LD, Sampath P, DiMeco F, Lawson HC, Tyler BM, Hanes J, Olivi A, Brem H.

Neurosurgery. 2003 Apr;52(4):872-9; discussion 879-80.

PMID:
12657184

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