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Items: 1 to 20 of 103

1.

A multivariate approach to predict the volumetric and gravimetric feeding behavior of a low feed rate feeder based on raw material properties.

Bostijn N, Dhondt J, Ryckaert A, Szabó E, Dhondt W, Van Snick B, Vanhoorne V, Vervaet C, De Beer T.

Int J Pharm. 2019 Feb 25;557:342-353. doi: 10.1016/j.ijpharm.2018.12.066. Epub 2018 Dec 29.

PMID:
30599227
2.

Managing active pharmaceutical ingredient raw material variability during twin-screw blend feeding.

Stauffer F, Vanhoorne V, Pilcer G, Chavez PF, Schubert MA, Vervaet C, De Beer T.

Eur J Pharm Biopharm. 2019 Feb;135:49-60. doi: 10.1016/j.ejpb.2018.12.012. Epub 2018 Dec 22.

PMID:
30582959
3.

Micro-feeding and dosing of powders via a small-scale powder pump.

Besenhard MO, Fathollahi S, Siegmann E, Slama E, Faulhammer E, Khinast JG.

Int J Pharm. 2017 Mar 15;519(1-2):314-322. doi: 10.1016/j.ijpharm.2016.12.029. Epub 2016 Dec 14.

PMID:
27986476
4.

Pharmaceutical excipients properties and screw feeder performance in continuous processing lines: a Quality by Design (QbD) approach.

Santos B, Carmo F, Schlindwein W, Muirhead G, Rodrigues C, Cabral L, Westrup J, Pitt K.

Drug Dev Ind Pharm. 2018 Dec;44(12):2089-2097. doi: 10.1080/03639045.2018.1513024. Epub 2018 Sep 19.

PMID:
30113219
5.

Real time monitoring of powder blend bulk density for coupled feed-forward/feed-back control of a continuous direct compaction tablet manufacturing process.

Singh R, Román-Ospino AD, Romañach RJ, Ierapetritou M, Ramachandran R.

Int J Pharm. 2015 Nov 10;495(1):612-625. doi: 10.1016/j.ijpharm.2015.09.029. Epub 2015 Sep 16.

PMID:
26386140
6.

Impact of material properties and process variables on the residence time distribution in twin screw feeding equipment.

Van Snick B, Kumar A, Verstraeten M, Pandelaere K, Dhondt J, Di Pretoro G, De Beer T, Vervaet C, Vanhoorne V.

Int J Pharm. 2019 Feb 10;556:200-216. doi: 10.1016/j.ijpharm.2018.11.076. Epub 2018 Dec 11.

PMID:
30550749
7.

Continuous manufacturing of a pharmaceutical cream: Investigating continuous powder dispersing and residence time distribution (RTD).

Bostijn N, Van Renterghem J, Vanbillemont B, Dhondt W, Vervaet C, De Beer T.

Eur J Pharm Sci. 2019 Apr 30;132:106-117. doi: 10.1016/j.ejps.2019.02.036. Epub 2019 Mar 1.

PMID:
30831193
8.

Continuous feeding of low-dose APIs via periodic micro dosing.

Besenhard MO, Karkala SK, Faulhammer E, Fathollahi S, Ramachandran R, Khinast JG.

Int J Pharm. 2016 Jul 25;509(1-2):123-134. doi: 10.1016/j.ijpharm.2016.05.033. Epub 2016 May 19.

PMID:
27210736
9.

Miniaturization in pharmaceutical extrusion technology: feeding as a challenge of downscaling.

Muehlenfeld C, Thommes M.

AAPS PharmSciTech. 2012 Mar;13(1):94-100. doi: 10.1208/s12249-011-9726-7. Epub 2011 Dec 9.

10.

Development of a design space and predictive statistical model for capsule filling of low-fill-weight inhalation products.

Faulhammer E, Llusa M, Wahl PR, Paudel A, Lawrence S, Biserni S, Calzolari V, Khinast JG.

Drug Dev Ind Pharm. 2016;42(2):221-30. doi: 10.3109/03639045.2015.1040416. Epub 2015 May 29.

PMID:
26023991
11.

Continuous powder feeding for pharmaceutical solid dosage form manufacture: a short review.

Blackshields CA, Crean AM.

Pharm Dev Technol. 2018 Jul;23(6):554-560. doi: 10.1080/10837450.2017.1339197. Epub 2017 Jun 21. Review.

PMID:
28590824
12.

Development of a continuous direct compression platform for low-dose drug products.

Van Snick B, Holman J, Vanhoorne V, Kumar A, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2017 Aug 30;529(1-2):329-346. doi: 10.1016/j.ijpharm.2017.07.003. Epub 2017 Jul 4.

PMID:
28684361
13.

A multivariate raw material property database to facilitate drug product development and enable in-silico design of pharmaceutical dry powder processes.

Van Snick B, Dhondt J, Pandelaere K, Bertels J, Mertens R, Klingeleers D, Di Pretoro G, Remon JP, Vervaet C, De Beer T, Vanhoorne V.

Int J Pharm. 2018 Oct 5;549(1-2):415-435. doi: 10.1016/j.ijpharm.2018.08.014. Epub 2018 Aug 14.

PMID:
30118831
14.

Use of the channel fill level in defining a design space for twin screw wet granulation.

Gorringe LJ, Kee GS, Saleh MF, Fa NH, Elkes RG.

Int J Pharm. 2017 Mar 15;519(1-2):165-177. doi: 10.1016/j.ijpharm.2017.01.029. Epub 2017 Jan 15.

PMID:
28099877
15.

Evaluation of the vibratory feeder method for assessment of powder flow properties.

Bhattachar SN, Hedden DB, Olsofsky AM, Qu X, Hsieh WY, Canter KG.

Int J Pharm. 2004 Jan 28;269(2):385-92.

PMID:
14706250
16.

Understanding effects of process parameters and forced feeding on die filling.

Goh HP, Heng PWS, Liew CV.

Eur J Pharm Sci. 2018 Sep 15;122:105-115. doi: 10.1016/j.ejps.2018.06.026. Epub 2018 Jun 27.

PMID:
29959985
17.

Low-dose capsule filling of inhalation products: critical material attributes and process parameters.

Faulhammer E, Fink M, Llusa M, Lawrence SM, Biserni S, Calzolari V, Khinast JG.

Int J Pharm. 2014 Oct 1;473(1-2):617-26. doi: 10.1016/j.ijpharm.2014.07.050. Epub 2014 Aug 1.

PMID:
25087508
18.

Development of a novel approach towards predicting the milling behaviour of pharmaceutical powders.

Kwan CC, Chen YQ, Ding YL, Papadopoulos DG, Bentham AC, Ghadiri M.

Eur J Pharm Sci. 2004 Dec;23(4-5):327-36.

PMID:
15567285
19.

Batch statistical process control of a fluid bed granulation process using in-line spatial filter velocimetry and product temperature measurements.

Burggraeve A, Van den Kerkhof T, Hellings M, Remon JP, Vervaet C, De Beer T.

Eur J Pharm Sci. 2011 Apr 18;42(5):584-92. doi: 10.1016/j.ejps.2011.03.002. Epub 2011 Mar 21.

PMID:
21397688
20.

Modelling and understanding powder flow properties and compactability of selected active pharmaceutical ingredients, excipients and physical mixtures from critical material properties.

Worku ZA, Kumar D, Gomes JV, He Y, Glennon B, Ramisetty KA, Rasmuson ÅC, O'Connell P, Gallagher KH, Woods T, Shastri NR, Healy AM.

Int J Pharm. 2017 Oct 5;531(1):191-204. doi: 10.1016/j.ijpharm.2017.08.063. Epub 2017 Aug 9.

PMID:
28801109

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