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Items: 1 to 20 of 103

1.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation.

Unsworth AJ, Bombik I, Pinto-Fernandez A, McGouran JF, Konietzny R, Zahedi RP, Watson SP, Kessler BM, Pears CJ.

Thromb Haemost. 2019 Jan;119(1):104-116. doi: 10.1055/s-0038-1676344. Epub 2018 Dec 31.

2.

Rapid ubiquitination of Syk following GPVI activation in platelets.

Dangelmaier CA, Quinter PG, Jin J, Tsygankov AY, Kunapuli SP, Daniel JL.

Blood. 2005 May 15;105(10):3918-24. Epub 2005 Feb 8.

3.

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.

Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.

Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. doi: 10.1074/mcp.M111.013284. Epub 2011 Sep 1.

4.

Roles of Src-like adaptor protein 2 (SLAP-2) in GPVI-mediated platelet activation SLAP-2 and GPVI signaling.

Sugihara S, Katsutani S, Deckmyn H, Fujimura K, Kimura A.

Thromb Res. 2010 Oct;126(4):e276-85. doi: 10.1016/j.thromres.2010.07.010. Epub 2010 Sep 15.

PMID:
20828795
5.

Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Moraes LA, Spyridon M, Kaiser WJ, Jones CI, Sage T, Atherton RE, Gibbins JM.

J Thromb Haemost. 2010 Mar;8(3):577-87. doi: 10.1111/j.1538-7836.2009.03732.x. Epub 2009 Dec 21.

6.

Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.

Wijeyewickrema LC, Gardiner EE, Moroi M, Berndt MC, Andrews RK.

Thromb Haemost. 2007 Dec;98(6):1285-90.

PMID:
18064326
7.

ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.

Arthur JF, Qiao J, Shen Y, Davis AK, Dunne E, Berndt MC, Gardiner EE, Andrews RK.

J Thromb Haemost. 2012 Jun;10(6):1133-41. doi: 10.1111/j.1538-7836.2012.04734.x.

8.

The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets.

Spalton JC, Mori J, Pollitt AY, Hughes CE, Eble JA, Watson SP.

J Thromb Haemost. 2009 Jul;7(7):1192-9. doi: 10.1111/j.1538-7836.2009.03451.x. Epub 2009 Apr 24.

9.

The toll-like receptor 2/1 (TLR2/1) complex initiates human platelet activation via the src/Syk/LAT/PLCγ2 signalling cascade.

Fälker K, Klarström-Engström K, Bengtsson T, Lindahl TL, Grenegård M.

Cell Signal. 2014 Feb;26(2):279-86. doi: 10.1016/j.cellsig.2013.11.011. Epub 2013 Nov 12.

PMID:
24240055
10.

C1q induces a rapid up-regulation of P-selectin and modulates collagen- and collagen-related peptide-triggered activation in human platelets.

Skoglund C, Wetterö J, Tengvall P, Bengtsson T.

Immunobiology. 2010 Dec;215(12):987-95. doi: 10.1016/j.imbio.2009.11.004. Epub 2010 Feb 16.

11.

Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.

Manne BK, Badolia R, Dangelmaier C, Eble JA, Ellmeier W, Kahn M, Kunapuli SP.

J Biol Chem. 2015 May 1;290(18):11557-68. doi: 10.1074/jbc.M114.629527. Epub 2015 Mar 12.

12.

Platelet collagen receptor Glycoprotein VI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation.

Induruwa I, Moroi M, Bonna A, Malcor JD, Howes JM, Warburton EA, Farndale RW, Jung SM.

J Thromb Haemost. 2018 Feb;16(2):389-404. doi: 10.1111/jth.13919. Epub 2018 Jan 15.

13.

GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk.

Hughan SC, Hughes CE, McCarty OJ, Schweighoffer E, Soultanova I, Ware J, Tybulewicz VL, Watson SP.

Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):422-9. Epub 2006 Nov 16.

14.

Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation.

Carrim N, Walsh TG, Consonni A, Torti M, Berndt MC, Metharom P.

PLoS One. 2014 Nov 21;9(11):e113679. doi: 10.1371/journal.pone.0113679. eCollection 2014.

15.
16.

Distinct contributions of glycoprotein VI and alpha(2)beta(1) integrin to the induction of platelet protein tyrosine phosphorylation and aggregation.

Kamiguti AS, Theakston RD, Watson SP, Bon C, Laing GD, Zuzel M.

Arch Biochem Biophys. 2000 Feb 15;374(2):356-62.

PMID:
10666318
17.

Targeted phosphotyrosine profiling of glycoprotein VI signaling implicates oligophrenin-1 in platelet filopodia formation.

Bleijerveld OB, van Holten TC, Preisinger C, van der Smagt JJ, Farndale RW, Kleefstra T, Willemsen MH, Urbanus RT, de Groot PG, Heck AJ, Roest M, Scholten A.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1538-43. doi: 10.1161/ATVBAHA.112.300916. Epub 2013 Apr 25.

PMID:
23619296
18.

A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets.

Thomas DH, Getz TM, Newman TN, Dangelmaier CA, Carpino N, Kunapuli SP, Tsygankov AY, Daniel JL.

Blood. 2010 Oct 7;116(14):2570-8. doi: 10.1182/blood-2010-02-268136. Epub 2010 Jun 28.

19.

Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane.

Arthur JF, Shen Y, Kahn ML, Berndt MC, Andrews RK, Gardiner EE.

J Biol Chem. 2007 Oct 19;282(42):30434-41. Epub 2007 Aug 9.

20.

Cyclic AMP-insensitive activation of c-Src and Syk protein-tyrosine kinases through platelet membrane glycoprotein VI.

Ichinohe T, Takayama H, Ezumi Y, Yanagi S, Yamamura H, Okuma M.

J Biol Chem. 1995 Nov 24;270(47):28029-36.

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