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Items: 1 to 20 of 103

1.

The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus.

Kim CJ, Lee CG, Jung JY, Ghosh A, Hasan SN, Hwang SM, Kang H, Lee C, Kim GC, Rudra D, Suh CH, Im SH.

Immunity. 2018 Dec 18;49(6):1034-1048.e8. doi: 10.1016/j.immuni.2018.10.012. Erratum in: Immunity. 2019 Jan 15;50(1):272.

PMID:
30566881
2.

Circulating TFH subset distribution is strongly affected in lupus patients with an active disease.

Le Coz C, Joublin A, Pasquali JL, Korganow AS, Dumortier H, Monneaux F.

PLoS One. 2013 Sep 19;8(9):e75319. doi: 10.1371/journal.pone.0075319. eCollection 2013.

3.

Increased interleukin 21 and follicular helper T-like cells and reduced interleukin 10+ B cells in patients with new-onset systemic lupus erythematosus.

Wang L, Zhao P, Ma L, Shan Y, Jiang Z, Wang J, Jiang Y.

J Rheumatol. 2014 Sep;41(9):1781-92. doi: 10.3899/jrheum.131025. Epub 2014 Jul 15.

PMID:
25028374
4.

[Role of circulating T follicular helper subsets and T follicular helper effector memory cells in systemic lupus erythematosus].

Liang YC, Yao Y, Zhang RJ, Shao M, Sun XL, Shi GX, Gao C, Yu D, He J.

Zhonghua Yi Xue Za Zhi. 2019 Jan 15;99(3):164-168. doi: 10.3760/cma.j.issn.0376-2491.2019.03.002. Chinese.

PMID:
30669756
5.

Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production.

Zhang X, Lindwall E, Gauthier C, Lyman J, Spencer N, Alarakhia A, Fraser A, Ing S, Chen M, Webb-Detiege T, Zakem J, Davis W, Choi YS, Quinet R.

Lupus. 2015 Aug;24(9):909-17. doi: 10.1177/0961203314567750. Epub 2015 Feb 5.

PMID:
25654980
6.

Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.

Mayeux J, Skaug B, Luo W, Russell LM, John S, Saelee P, Abbasi H, Li QZ, Garrett-Sinha LA, Satterthwaite AB.

J Immunol. 2015 Sep 1;195(5):1955-63. doi: 10.4049/jimmunol.1500165. Epub 2015 Jul 24.

7.

A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels.

Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, Parnes J, Rickert R, Nitschke L, Cambier J, Satterthwaite AB, Garrett-Sinha LA.

J Immunol. 2014 Jul 15;193(2):909-920. doi: 10.4049/jimmunol.1400666. Epub 2014 Jun 13.

8.

Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor.

Keszei M, Detre C, Castro W, Magelky E, O'Keeffe M, Kis-Toth K, Tsokos GC, Wang N, Terhorst C.

FASEB J. 2013 Aug;27(8):3123-31. doi: 10.1096/fj.12-226951. Epub 2013 Apr 29.

9.

Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus.

Dang J, Shan S, Li J, Zhao H, Xin Q, Liu Y, Bian X, Liu Q.

Tissue Antigens. 2014 Jun;83(6):401-8. doi: 10.1111/tan.12349. Epub 2014 Apr 3.

PMID:
24697319
10.

Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production.

Morita K, Okamura T, Inoue M, Komai T, Teruya S, Iwasaki Y, Sumitomo S, Shoda H, Yamamoto K, Fujio K.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8131-E8140. Epub 2016 Nov 30.

11.

The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.

Yi W, Gupta S, Ricker E, Manni M, Jessberger R, Chinenov Y, Molina H, Pernis AB.

Nat Commun. 2017 Aug 15;8(1):254. doi: 10.1038/s41467-017-00348-3.

12.

Epistatic interaction between genetic variants in susceptibility gene ETS1 correlates with IL-17 levels in SLE patients.

Zhang J, Zhang Y, Zhang L, Yang J, Ying D, Zeng S, Lee TL, Lau CS, Chan TM, Leung AM, Mok CC, Wong SN, Lee KW, Ho MH, Lee PP, Chung BH, Chong CY, Wong RW, Mok MY, Wong WH, Lau YL, Yang W.

Ann Hum Genet. 2013 Jul;77(4):344-50. doi: 10.1111/ahg.12018. Epub 2013 Apr 24.

13.

A comprehensive investigation on the distribution of circulating follicular T helper cells and B cell subsets in primary Sjögren's syndrome and systemic lupus erythematosus.

Szabó K, Papp G, Szántó A, Tarr T, Zeher M.

Clin Exp Immunol. 2016 Jan;183(1):76-89. doi: 10.1111/cei.12703. Epub 2015 Oct 21.

14.

B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis.

Cortini A, Ellinghaus U, Malik TH, Cunninghame Graham DS, Botto M, Vyse TJ.

Ann Rheum Dis. 2017 Dec;76(12):2095-2103. doi: 10.1136/annrheumdis-2017-211499. Epub 2017 Aug 17.

15.

Circulating follicular helper-like T cells in systemic lupus erythematosus: association with disease activity.

Choi JY, Ho JH, Pasoto SG, Bunin V, Kim ST, Carrasco S, Borba EF, Gonçalves CR, Costa PR, Kallas EG, Bonfa E, Craft J.

Arthritis Rheumatol. 2015 Apr;67(4):988-99. doi: 10.1002/art.39020.

16.

Pathogenic Th2-type follicular helper T cells contribute to the development of lupus in Fas-deficient mice.

Futatsugi-Yumikura S, Matsushita K, Fukuoka A, Takahashi S, Yamamoto N, Yonehara S, Nakanishi K, Yoshimoto T.

Int Immunol. 2014 Apr;26(4):221-31. doi: 10.1093/intimm/dxt070. Epub 2013 Dec 16.

PMID:
24343821
17.

Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.

Serre K, Bénézech C, Desanti G, Bobat S, Toellner KM, Bird R, Chan S, Kastner P, Cunningham AF, Maclennan IC, Mohr E.

PLoS One. 2011;6(6):e20731. doi: 10.1371/journal.pone.0020731. Epub 2011 Jun 3.

18.

B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.

Arkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW.

J Exp Med. 2017 Nov 6;214(11):3207-3217. doi: 10.1084/jem.20170580. Epub 2017 Sep 12.

19.

Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.

Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC.

Am J Hum Genet. 2015 May 7;96(5):731-9. doi: 10.1016/j.ajhg.2015.03.002. Epub 2015 Apr 9.

20.

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus.

Simpson N, Gatenby PA, Wilson A, Malik S, Fulcher DA, Tangye SG, Manku H, Vyse TJ, Roncador G, Huttley GA, Goodnow CC, Vinuesa CG, Cook MC.

Arthritis Rheum. 2010 Jan;62(1):234-44. doi: 10.1002/art.25032.

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