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Items: 1 to 20 of 122

1.

Looking at Marine-Derived Bioactive Molecules as Upcoming Anti-Diabetic Agents: A Special Emphasis on PTP1B Inhibitors.

Ezzat SM, Bishbishy MHE, Habtemariam S, Salehi B, Sharifi-Rad M, Martins N, Sharifi-Rad J.

Molecules. 2018 Dec 15;23(12). pii: E3334. doi: 10.3390/molecules23123334. Review.

2.

α-Methyl artoflavanocoumarin from Juniperus chinensis exerts anti-diabetic effects by inhibiting PTP1B and activating the PI3K/Akt signaling pathway in insulin-resistant HepG2 cells.

Jung HJ, Seong SH, Ali MY, Min BS, Jung HA, Choi JS.

Arch Pharm Res. 2017 Dec;40(12):1403-1413. doi: 10.1007/s12272-017-0992-0. Epub 2017 Nov 24.

PMID:
29177868
3.

PTP1b Inhibition, A Promising Approach for the Treatment of Diabetes Type II.

Eleftheriou P, Geronikaki A, Petrou A.

Curr Top Med Chem. 2019;19(4):246-263. doi: 10.2174/1568026619666190201152153. Review.

PMID:
30714526
4.

Docking Assisted Prediction and Biological Evaluation of Sideritis L. Components with PTP1b Inhibitory Action and Probable Anti-Diabetic Properties.

Eleftheriou P, Therianou E, Lazari D, Dirnali S, Micha A.

Curr Top Med Chem. 2019;19(5):383-392. doi: 10.2174/1568026619666190219104430.

PMID:
30806317
5.

Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice.

Liu ZQ, Liu T, Chen C, Li MY, Wang ZY, Chen RS, Wei GX, Wang XY, Luo DQ.

Toxicol Appl Pharmacol. 2015 May 15;285(1):61-70. doi: 10.1016/j.taap.2015.03.011. Epub 2015 Mar 18.

PMID:
25796170
6.

Small molecules as potent protein tyrosine phosphatase 1B (PTP1B) inhibitors documented in patents from 2009 to 2013.

Wang LJ, Jiang B, Wu N, Wang SY, Shi DY.

Mini Rev Med Chem. 2015;15(2):104-22.

PMID:
25643610
7.
8.
9.

Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice.

Sun J, Fu X, Liu Y, Wang Y, Huo B, Guo Y, Gao X, Li W, Hu X.

Drug Des Devel Ther. 2015 Dec 4;9:6327-42. doi: 10.2147/DDDT.S92777. eCollection 2015.

10.

Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes.

Sun W, Zhang B, Zheng H, Zhuang C, Li X, Lu X, Quan C, Dong Y, Zheng Z, Xiu Z.

Life Sci. 2017 Jan 15;169:52-64. doi: 10.1016/j.lfs.2016.11.012. Epub 2016 Nov 19.

PMID:
27871946
11.

α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium.

Ali MY, Kim DH, Seong SH, Kim HR, Jung HA, Choi JS.

Mar Drugs. 2017 Dec 1;15(12). pii: E368. doi: 10.3390/md15120368.

12.

BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes.

Xu Q, Luo J, Wu N, Zhang R, Shi D.

Int J Biol Macromol. 2018 Jan;106:379-386. doi: 10.1016/j.ijbiomac.2017.08.042. Epub 2017 Aug 12.

PMID:
28811203
13.

Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B.

Kim DH, Paudel P, Yu T, Ngo TM, Kim JA, Jung HA, Yokozawa T, Choi JS.

Chem Biol Interact. 2017 Dec 25;278:65-73. doi: 10.1016/j.cbi.2017.10.013. Epub 2017 Oct 12.

PMID:
29031618
14.

Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.

Liu P, Du Y, Song L, Shen J, Li Q.

Eur J Med Chem. 2016 Aug 8;118:27-33. doi: 10.1016/j.ejmech.2016.04.014. Epub 2016 Apr 9.

PMID:
27123900
15.

Evaluation of 147 Kampo prescriptions as novel protein tyrosine phosphatase 1B (PTP1B) inhibitory agents.

Onoda T, Li W, Higai K, Koike K.

BMC Complement Altern Med. 2014 Feb 20;14:64. doi: 10.1186/1472-6882-14-64.

16.

Recent advances in the development of protein tyrosine phosphatase 1B inhibitors for Type 2 diabetes.

Qian S, Zhang M, He Y, Wang W, Liu S.

Future Med Chem. 2016 Jul;8(11):1239-58. doi: 10.4155/fmc-2016-0064. Epub 2016 Jun 30. Review.

PMID:
27357615
17.

Coumarins from Angelica decursiva inhibit α-glucosidase activity and protein tyrosine phosphatase 1B.

Ali MY, Jannat S, Jung HA, Jeong HO, Chung HY, Choi JS.

Chem Biol Interact. 2016 May 25;252:93-101. doi: 10.1016/j.cbi.2016.04.020. Epub 2016 Apr 13.

PMID:
27085377
18.

Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study.

Proença C, Freitas M, Ribeiro D, Sousa JLC, Carvalho F, Silva AMS, Fernandes PA, Fernandes E.

Food Chem Toxicol. 2018 Jan;111:474-481. doi: 10.1016/j.fct.2017.11.039. Epub 2017 Nov 22.

PMID:
29175190
19.

PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011 - 2014).

Tamrakar AK, Maurya CK, Rai AK.

Expert Opin Ther Pat. 2014 Oct;24(10):1101-15. doi: 10.1517/13543776.2014.947268. Epub 2014 Aug 14. Review.

PMID:
25120222
20.

QSAR studies of PTP1B inhibitors: recent advances and perspectives.

Luan F, Xu X, Liu HT, Cordeiro MN, Zhang XY.

Curr Med Chem. 2012;19(25):4208-17.

PMID:
22834811

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