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A new model to predict ischemic stroke in patients with atrial fibrillation using warfarin or direct oral anticoagulants.

Claxton JS, MacLehose RF, Lutsey PL, Norby FL, Chen LY, O'Neal WT, Chamberlain AM, Bengtson LGS, Alonso A.

Heart Rhythm. 2019 Jun;16(6):820-826. doi: 10.1016/j.hrthm.2018.12.005. Epub 2018 Dec 12.


A new model to predict major bleeding in patients with atrial fibrillation using warfarin or direct oral anticoagulants.

Claxton JS, MacLehose RF, Lutsey PL, Norby FL, Chen LY, O'Neal WT, Chamberlain AM, Bengtson LGS, Alonso A.

PLoS One. 2018 Sep 10;13(9):e0203599. doi: 10.1371/journal.pone.0203599. eCollection 2018.


The HAS-BLED score has better prediction accuracy for major bleeding than CHADS2 or CHA2DS2-VASc scores in anticoagulated patients with atrial fibrillation.

Roldán V, Marín F, Manzano-Fernández S, Gallego P, Vílchez JA, Valdés M, Vicente V, Lip GY.

J Am Coll Cardiol. 2013 Dec 10;62(23):2199-204. doi: 10.1016/j.jacc.2013.08.1623. Epub 2013 Sep 18.


Comparative Performance of ATRIA, CHADS2, and CHA2DS2-VASc Risk Scores Predicting Stroke in Patients With Atrial Fibrillation: Results From a National Primary Care Database.

van den Ham HA, Klungel OH, Singer DE, Leufkens HG, van Staa TP.

J Am Coll Cardiol. 2015 Oct 27;66(17):1851-9. doi: 10.1016/j.jacc.2015.08.033.


Stroke Prevention in Atrial Fibrillation [Internet].

Lopes RD, Crowley MJ, Shah BR, Melloni C, Wood KA, Chatterjee R, Povsic TJ, Dupre ME, Kong DF, de Barros e Silva PGM, dos Santos MHH, Armaganijan LV, Katz M, Kosinski A, McBroom AJ, Chobot MM, Gray R, Sanders GD.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Aug.


Ischemic Stroke Risk in Patients With Atrial Fibrillation and CHA2DS2-VASc Score of 1: Systematic Review and Meta-Analysis.

Joundi RA, Cipriano LE, Sposato LA, Saposnik G; Stroke Outcomes Research Working Group.

Stroke. 2016 May;47(5):1364-7. doi: 10.1161/STROKEAHA.115.012609. Epub 2016 Mar 29. Review.


CHA2DS2-VASc Score for Identifying Truly Low-Risk Atrial Fibrillation for Stroke: A Korean Nationwide Cohort Study.

Kim TH, Yang PS, Kim D, Yu HT, Uhm JS, Kim JY, Pak HN, Lee MH, Joung B, Lip GYH.

Stroke. 2017 Nov;48(11):2984-2990. doi: 10.1161/STROKEAHA.117.018551. Epub 2017 Sep 22.


Improved risk stratification of patients with atrial fibrillation: an integrated GARFIELD-AF tool for the prediction of mortality, stroke and bleed in patients with and without anticoagulation.

Fox KAA, Lucas JE, Pieper KS, Bassand JP, Camm AJ, Fitzmaurice DA, Goldhaber SZ, Goto S, Haas S, Hacke W, Kayani G, Oto A, Mantovani LG, Misselwitz F, Piccini JP, Turpie AGG, Verheugt FWA, Kakkar AK; GARFIELD-AF Investigators.

BMJ Open. 2017 Dec 21;7(12):e017157. doi: 10.1136/bmjopen-2017-017157.


Validation of a Modified CHA2DS2-VASc Score for Stroke Risk Stratification in Asian Patients With Atrial Fibrillation: A Nationwide Cohort Study.

Chao TF, Lip GY, Liu CJ, Tuan TC, Chen SJ, Wang KL, Lin YJ, Chang SL, Lo LW, Hu YF, Chen TJ, Chiang CE, Chen SA.

Stroke. 2016 Oct;47(10):2462-9. doi: 10.1161/STROKEAHA.116.013880. Epub 2016 Sep 13.


Adherence to treatment guidelines: the association between stroke risk stratified comparing CHADS2 and CHA2DS2-VASc score levels and warfarin prescription for adult patients with atrial fibrillation.

Chapman SA, St Hill CA, Little MM, Swanoski MT, Scheiner SR, Ware KB, Lutfiyya MN.

BMC Health Serv Res. 2017 Feb 11;17(1):127. doi: 10.1186/s12913-017-2025-6.


Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts.

Piccini JP, Stevens SR, Chang Y, Singer DE, Lokhnygina Y, Go AS, Patel MR, Mahaffey KW, Halperin JL, Breithardt G, Hankey GJ, Hacke W, Becker RC, Nessel CC, Fox KA, Califf RM; ROCKET AF Steering Committee and Investigators.

Circulation. 2013 Jan 15;127(2):224-32. doi: 10.1161/CIRCULATIONAHA.112.107128. Epub 2012 Dec 3.


Is an Oral Anticoagulant Necessary for Young Atrial Fibrillation Patients With a CHA2DS2-VASc Score of 1 (Men) or 2 (Women)?

Hung Y, Chao TF, Liu CJ, Tuan TC, Lin YJ, Chang SL, Lo LW, Hu YF, Liao JN, Chung FP, Lin WY, Lin WS, Cheng SM, Chen TJ, Lip GY, Chen SA.

J Am Heart Assoc. 2016 Oct 4;5(10). pii: e003839.


Should atrial fibrillation patients with 1 additional risk factor of the CHA2DS2-VASc score (beyond sex) receive oral anticoagulation?

Chao TF, Liu CJ, Wang KL, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Chen TJ, Lip GY, Chen SA.

J Am Coll Cardiol. 2015 Feb 24;65(7):635-42. doi: 10.1016/j.jacc.2014.11.046.


Incidence and prediction of ischemic stroke among atrial fibrillation patients with end-stage renal disease requiring dialysis.

Chao TF, Liu CJ, Wang KL, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Chung FP, Liao JN, Chen TJ, Lip GY, Chen SA.

Heart Rhythm. 2014 Oct;11(10):1752-9. doi: 10.1016/j.hrthm.2014.06.021. Epub 2014 Jun 18.


Wide Variation in Reported Rates of Stroke Across Cohorts of Patients With Atrial Fibrillation.

Quinn GR, Severdija ON, Chang Y, Singer DE.

Circulation. 2017 Jan 17;135(3):208-219. doi: 10.1161/CIRCULATIONAHA.116.024057. Epub 2016 Oct 31.


Assessment of the CHA2DS2-VASc Score in Predicting Ischemic Stroke, Thromboembolism, and Death in Patients With Heart Failure With and Without Atrial Fibrillation.

Melgaard L, Gorst-Rasmussen A, Lane DA, Rasmussen LH, Larsen TB, Lip GY.

JAMA. 2015 Sep 8;314(10):1030-8. doi: 10.1001/jama.2015.10725.


A Real-World Observational Study of Hospitalization and Health Care Costs Among Nonvalvular Atrial Fibrillation Patients Prescribed Oral Anticoagulants in the U.S. Medicare Population.

Amin A, Keshishian A, Trocio J, Dina O, Le H, Rosenblatt L, Liu X, Mardekian J, Zhang Q, Baser O, Nadkarni A, Vo L.

J Manag Care Spec Pharm. 2018 Sep;24(9):911-920. doi: 10.18553/jmcp.2018.24.9.911.


Meta-analysis of CHADS2 versus CHA2DS2-VASc for predicting stroke and thromboembolism in atrial fibrillation patients independent of anticoagulation.

Zhu WG, Xiong QM, Hong K.

Tex Heart Inst J. 2015 Feb 1;42(1):6-15. doi: 10.14503/THIJ-14-4353. eCollection 2015 Feb. Review.


The CHADS2 and CHA 2DS 2-VASc scores predict new occurrence of atrial fibrillation and ischemic stroke.

Zuo ML, Liu S, Chan KH, Lau KK, Chong BH, Lam KF, Chan YH, Lau YF, Lip GY, Lau CP, Tse HF, Siu CW.

J Interv Card Electrophysiol. 2013 Jun;37(1):47-54. doi: 10.1007/s10840-012-9776-0. Epub 2013 Feb 7.


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