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Items: 1 to 20 of 102

1.

Modulation of Protein Synthesis by eIF2α Phosphorylation Protects Cell from Heat Stress-Mediated Apoptosis.

Park S, Lim Y, Lee D, Elvira R, Lee JM, Lee MR, Han J.

Cells. 2018 Dec 7;7(12). pii: E254. doi: 10.3390/cells7120254.

2.

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.

Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.

Biochem Pharmacol. 2016 Jun 1;109:27-47. doi: 10.1016/j.bcp.2016.04.001. Epub 2016 Apr 6.

PMID:
27059255
3.

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.

Hulmi JJ, Hentilä J, DeRuisseau KC, Oliveira BM, Papaioannou KG, Autio R, Kujala UM, Ritvos O, Kainulainen H, Korkmaz A, Atalay M.

Free Radic Biol Med. 2016 Oct;99:308-322. doi: 10.1016/j.freeradbiomed.2016.08.017. Epub 2016 Aug 20.

PMID:
27554968
4.

O-GlcNAcylation of eIF2α regulates the phospho-eIF2α-mediated ER stress response.

Jang I, Kim HB, Seo H, Kim JY, Choi H, Yoo JS, Kim JW, Cho JW.

Biochim Biophys Acta. 2015 Aug;1853(8):1860-9. doi: 10.1016/j.bbamcr.2015.04.017. Epub 2015 Apr 30.

5.

Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.

Guan BJ, Krokowski D, Majumder M, Schmotzer CL, Kimball SR, Merrick WC, Koromilas AE, Hatzoglou M.

J Biol Chem. 2014 May 2;289(18):12593-611. doi: 10.1074/jbc.M113.543215. Epub 2014 Mar 19.

6.

Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells.

Cnop M, Toivonen S, Igoillo-Esteve M, Salpea P.

Mol Metab. 2017 Jul 12;6(9):1024-1039. doi: 10.1016/j.molmet.2017.06.001. eCollection 2017 Sep. Review.

7.

A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells.

Hosoi T, Kume A, Otani K, Oba T, Ozawa K.

Br J Pharmacol. 2010 Jan 1;159(2):428-37. doi: 10.1111/j.1476-5381.2009.00544.x. Epub 2009 Dec 15.

8.

Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors.

Drexler HC.

PLoS One. 2009;4(1):e4161. doi: 10.1371/journal.pone.0004161. Epub 2009 Jan 8.

9.

Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: protective role of mild heat preconditioning at 40°C.

Pallepati P, Averill-Bates DA.

Biochim Biophys Acta. 2011 Dec;1813(12):1987-99. doi: 10.1016/j.bbamcr.2011.07.021. Epub 2011 Aug 22.

10.

The endoplasmic reticulum stress sensor IRE1α protects cells from apoptosis induced by the coronavirus infectious bronchitis virus.

Fung TS, Liao Y, Liu DX.

J Virol. 2014 Nov;88(21):12752-64. doi: 10.1128/JVI.02138-14. Epub 2014 Aug 20.

11.

A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation.

Majumder M, Huang C, Snider MD, Komar AA, Tanaka J, Kaufman RJ, Krokowski D, Hatzoglou M.

Mol Cell Biol. 2012 Mar;32(5):992-1003. doi: 10.1128/MCB.06665-11. Epub 2012 Jan 3.

12.

The PERK-eIF2α signaling pathway is involved in TCDD-induced ER stress in PC12 cells.

Duan Z, Zhao J, Fan X, Tang C, Liang L, Nie X, Liu J, Wu Q, Xu G.

Neurotoxicology. 2014 Sep;44:149-59. doi: 10.1016/j.neuro.2014.06.005. Epub 2014 Jun 14.

PMID:
24932542
13.

6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.

Hu R, Zhou P, Peng YB, Xu X, Ma J, Liu Q, Zhang L, Wen XD, Qi LW, Gao N, Li P.

PLoS One. 2012;7(6):e39664. doi: 10.1371/journal.pone.0039664. Epub 2012 Jun 29.

14.

Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.

Manni S, Brancalion A, Tubi LQ, Colpo A, Pavan L, Cabrelle A, Ave E, Zaffino F, Di Maira G, Ruzzene M, Adami F, Zambello R, Pitari MR, Tassone P, Pinna LA, Gurrieri C, Semenzato G, Piazza F.

Clin Cancer Res. 2012 Apr 1;18(7):1888-900. doi: 10.1158/1078-0432.CCR-11-1789. Epub 2012 Feb 20.

15.

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response.

Hiramatsu N, Messah C, Han J, LaVail MM, Kaufman RJ, Lin JH.

Mol Biol Cell. 2014 May;25(9):1411-20. doi: 10.1091/mbc.E13-11-0664. Epub 2014 Mar 12.

16.

ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis.

Thomas CG, Spyrou G.

J Biol Chem. 2009 Mar 6;284(10):6282-90. doi: 10.1074/jbc.M806189200. Epub 2009 Jan 4.

17.

Nuclear Matrix Protein 4 Is a Novel Regulator of Ribosome Biogenesis and Controls the Unfolded Protein Response via Repression of Gadd34 Expression.

Young SK, Shao Y, Bidwell JP, Wek RC.

J Biol Chem. 2016 Jun 24;291(26):13780-8. doi: 10.1074/jbc.M116.729830. Epub 2016 Apr 29.

18.

SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation.

Prola A, Pires Da Silva J, Guilbert A, Lecru L, Piquereau J, Ribeiro M, Mateo P, Gressette M, Fortin D, Boursier C, Gallerne C, Caillard A, Samuel JL, François H, Sinclair DA, Eid P, Ventura-Clapier R, Garnier A, Lemaire C.

Cell Death Differ. 2017 Feb;24(2):343-356. doi: 10.1038/cdd.2016.138. Epub 2016 Dec 2.

19.

IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.

So JS, Cho S, Min SH, Kimball SR, Lee AH.

Mol Cell Biol. 2015 Aug;35(16):2761-70. doi: 10.1128/MCB.00215-15. Epub 2015 Jun 1.

20.

ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice.

Han J, Murthy R, Wood B, Song B, Wang S, Sun B, Malhi H, Kaufman RJ.

Diabetologia. 2013 Apr;56(4):911-24. doi: 10.1007/s00125-012-2809-5. Epub 2013 Jan 12.

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