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Items: 1 to 20 of 94

1.

NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex.

Aikawa C, Nakajima S, Karimine M, Nozawa T, Minowa-Nozawa A, Toh H, Yamada S, Nakagawa I.

Front Cell Infect Microbiol. 2018 Nov 14;8:403. doi: 10.3389/fcimb.2018.00403. eCollection 2018.

2.

Bcl-xL Affects Group A Streptococcus-Induced Autophagy Directly, by Inhibiting Fusion between Autophagosomes and Lysosomes, and Indirectly, by Inhibiting Bacterial Internalization via Interaction with Beclin 1-UVRAG.

Nakajima S, Aikawa C, Nozawa T, Minowa-Nozawa A, Toh H, Nakagawa I.

PLoS One. 2017 Jan 13;12(1):e0170138. doi: 10.1371/journal.pone.0170138. eCollection 2017.

3.

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.

Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M.

Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1. Review.

PMID:
23827971
4.

NLRP4 negatively regulates autophagic processes through an association with beclin1.

Jounai N, Kobiyama K, Shiina M, Ogata K, Ishii KJ, Takeshita F.

J Immunol. 2011 Feb 1;186(3):1646-55. doi: 10.4049/jimmunol.1001654. Epub 2011 Jan 5.

5.

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.

Wu S, He Y, Qiu X, Yang W, Liu W, Li X, Li Y, Shen HM, Wang R, Yue Z, Zhao Y.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5669-E5678. doi: 10.1073/pnas.1721173115. Epub 2018 Jun 4.

6.

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP.

Immunity. 2012 Jun 29;36(6):933-46. doi: 10.1016/j.immuni.2012.03.025.

7.

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, Jung JU.

Nat Cell Biol. 2008 Jul;10(7):776-87. doi: 10.1038/ncb1740. Epub 2008 Jun 15.

8.

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z.

PLoS Genet. 2014 Oct 2;10(10):e1004626. doi: 10.1371/journal.pgen.1004626. eCollection 2014 Oct.

9.

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.

Itakura E, Kishi C, Inoue K, Mizushima N.

Mol Biol Cell. 2008 Dec;19(12):5360-72. doi: 10.1091/mbc.E08-01-0080. Epub 2008 Oct 8.

10.

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.

Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19211-6. doi: 10.1073/pnas.0810452105. Epub 2008 Dec 2.

11.

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.

Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU.

Nat Cell Biol. 2006 Jul;8(7):688-99. Epub 2006 Jun 25.

PMID:
16799551
12.

Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.

Li X, He L, Che KH, Funderburk SF, Pan L, Pan N, Zhang M, Yue Z, Zhao Y.

Nat Commun. 2012 Feb 7;3:662. doi: 10.1038/ncomms1648.

13.

Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.

Zhong Y, Morris DH, Jin L, Patel MS, Karunakaran SK, Fu YJ, Matuszak EA, Weiss HL, Chait BT, Wang QJ.

J Biol Chem. 2014 Sep 19;289(38):26021-37. doi: 10.1074/jbc.M114.561134. Epub 2014 Aug 1.

14.

LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy.

Lin CY, Nozawa T, Minowa-Nozawa A, Toh H, Aikawa C, Nakagawa I.

Cell Microbiol. 2019 Apr;21(4):e12981. doi: 10.1111/cmi.12981. Epub 2019 Jan 21.

PMID:
30428163
15.

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C, Jung JU, Cheng JQ, Mulé JJ, Pledger WJ, Wang HG.

Nat Cell Biol. 2007 Oct;9(10):1142-51. Epub 2007 Sep 23.

16.

Beyond autophagy: the role of UVRAG in membrane trafficking.

Liang C, Sir D, Lee S, Ou JH, Jung JU.

Autophagy. 2008 Aug;4(6):817-20. Epub 2008 Jun 25.

17.

NLRX1 of black carp suppresses MAVS-mediated antiviral signaling through its NACHT domain.

Song X, Li W, Xie X, Zou Z, Wei J, Wu H, Feng H.

Dev Comp Immunol. 2019 Jul;96:68-77. doi: 10.1016/j.dci.2019.03.001. Epub 2019 Mar 7.

PMID:
30853538
18.

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex.

He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh S, Lee WH, Takahashi Y, Wang HG, Minassian A, Feng P, Deretic V, Pepperkok R, Tagaya M, Yoon HS, Liang C.

Nat Cell Biol. 2013 Oct;15(10):1206-1219. doi: 10.1038/ncb2848. Epub 2013 Sep 22.

19.

Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment.

Adi-Harel S, Erlich S, Schmukler E, Cohen-Kedar S, Segev O, Mizrachy L, Hirsch JA, Pinkas-Kramarski R.

J Cell Biochem. 2010 Aug 1;110(5):1262-71. doi: 10.1002/jcb.22642.

PMID:
20564222
20.

Reactive Oxygen Species-Mediated c-Jun NH2-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction.

Zhong L, Shu W, Dai W, Gao B, Xiong S.

J Virol. 2017 Jul 12;91(15). pii: e00001-17. doi: 10.1128/JVI.00001-17. Print 2017 Aug 1.

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