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Items: 1 to 20 of 106

1.

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG; 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A.

Nat Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26.

2.

Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?

Hart AB, Lynch KG, Farrer L, Gelernter J, Kranzler HR.

Addict Biol. 2016 Jul;21(4):924-38. doi: 10.1111/adb.12244. Epub 2015 Apr 1.

3.

Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

Polimanti R, Zhao H, Farrer LA, Kranzler HR, Gelernter J.

Am J Med Genet B Neuropsychiatr Genet. 2017 Dec;174(8):846-853. doi: 10.1002/ajmg.b.32604. Epub 2017 Oct 9.

4.

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria.

Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI Jr, Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hariri AR, Edenberg HJ, Agrawal A, Bogdan R, Porjesz B, Goate AM, Foroud T.

Genes Brain Behav. 2019 Jul;18(6):e12579. doi: 10.1111/gbb.12579. Epub 2019 Jun 4.

PMID:
31090166
5.

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA.

Mol Psychiatry. 2014 Jan;19(1):41-9. doi: 10.1038/mp.2013.145. Epub 2013 Oct 29.

6.

Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.

Jorgenson E, Thai KK, Hoffmann TJ, Sakoda LC, Kvale MN, Banda Y, Schaefer C, Risch N, Mertens J, Weisner C, Choquet H.

Mol Psychiatry. 2017 Sep;22(9):1359-1367. doi: 10.1038/mp.2017.101. Epub 2017 May 9.

7.

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence.

Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI Jr, Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, Porjesz B, Dick DM, Hesselbrock V, Boerwinkle E, Southwick SM, Krystal JH, Weissman MM, Levinson DF, Potash JB, Gelernter J, Han S.

JAMA Psychiatry. 2017 Nov 1;74(11):1153-1160. doi: 10.1001/jamapsychiatry.2017.2269.

8.

Family-based association analysis of alcohol dependence criteria and severity.

Wetherill L, Kapoor M, Agrawal A, Bucholz K, Koller D, Bertelsen SE, Le N, Wang JC, Almasy L, Hesselbrock V, Kramer J, Nurnberger JI Jr, Schuckit M, Tischfield JA, Xuei X, Porjesz B, Edenberg HJ, Goate AM, Foroud T.

Alcohol Clin Exp Res. 2014 Feb;38(2):354-66. doi: 10.1111/acer.12251. Epub 2013 Sep 9.

9.

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses.

Hart AB, Kranzler HR.

Alcohol Clin Exp Res. 2015 Aug;39(8):1312-27. doi: 10.1111/acer.12792. Epub 2015 Jun 25. Review.

10.

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.

Park BL, Kim JW, Cheong HS, Kim LH, Lee BC, Seo CH, Kang TC, Nam YW, Kim GB, Shin HD, Choi IG.

Hum Genet. 2013 Jun;132(6):657-68. doi: 10.1007/s00439-013-1281-8. Epub 2013 Mar 1.

PMID:
23456092
11.

Genome-wide association study of comorbid depressive syndrome and alcohol dependence.

Edwards AC, Aliev F, Bierut LJ, Bucholz KK, Edenberg H, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI Jr, Schuckit MA, Porjesz B, Dick DM.

Psychiatr Genet. 2012 Feb;22(1):31-41. doi: 10.1097/YPG.0b013e32834acd07.

12.

Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders.

Cho SB, Aliev F, Clark SL, Adkins AE, Edenberg HJ, Bucholz KK, Porjesz B, Dick DM.

Behav Genet. 2017 Jul;47(4):405-415. doi: 10.1007/s10519-017-9844-4. Epub 2017 Mar 25.

13.

Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.

Nievergelt CM, Maihofer AX, Mustapic M, Yurgil KA, Schork NJ, Miller MW, Logue MW, Geyer MA, Risbrough VB, O'Connor DT, Baker DG.

Psychoneuroendocrinology. 2015 Jan;51:459-71. doi: 10.1016/j.psyneuen.2014.10.017. Epub 2014 Oct 30.

PMID:
25456346
14.

Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures.

Kapoor M, Chou YL, Edenberg HJ, Foroud T, Martin NG, Madden PA, Wang JC, Bertelsen S, Wetherill L, Brooks A, Chan G, Hesselbrock V, Kuperman S, Medland SE, Montgomery G, Tischfield J, Whitfield JB, Bierut LJ, Heath AC, Bucholz KK, Goate AM, Agrawal A.

Transl Psychiatry. 2016 Mar 22;6:e761. doi: 10.1038/tp.2016.27.

15.

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.

Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Almasy L, Bucholz K, Dick DM, Harari O, Xiaoling X, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A.

Drug Alcohol Depend. 2014 Sep 1;142:56-62. doi: 10.1016/j.drugalcdep.2014.05.023. Epub 2014 Jun 11.

16.

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

Zhou H, Polimanti R, Yang BZ, Wang Q, Han S, Sherva R, Nuñez YZ, Zhao H, Farrer LA, Kranzler HR, Gelernter J.

JAMA Psychiatry. 2017 Dec 1;74(12):1234-1241. doi: 10.1001/jamapsychiatry.2017.3275.

17.

A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.

Heath AC, Whitfield JB, Martin NG, Pergadia ML, Goate AM, Lind PA, McEvoy BP, Schrage AJ, Grant JD, Chou YL, Zhu R, Henders AK, Medland SE, Gordon SD, Nelson EC, Agrawal A, Nyholt DR, Bucholz KK, Madden PA, Montgomery GW.

Biol Psychiatry. 2011 Sep 15;70(6):513-8. doi: 10.1016/j.biopsych.2011.02.028. Epub 2011 May 6.

18.

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.

Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Bucholz K, Dick D, Harari O, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Saccone N, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A.

Hum Genet. 2013 Oct;132(10):1141-51. doi: 10.1007/s00439-013-1318-z. Epub 2013 Jun 7.

19.

Genome-wide association study of alcohol dependence.

Treutlein J, Cichon S, Ridinger M, Wodarz N, Soyka M, Zill P, Maier W, Moessner R, Gaebel W, Dahmen N, Fehr C, Scherbaum N, Steffens M, Ludwig KU, Frank J, Wichmann HE, Schreiber S, Dragano N, Sommer WH, Leonardi-Essmann F, Lourdusamy A, Gebicke-Haerter P, Wienker TF, Sullivan PF, Nöthen MM, Kiefer F, Spanagel R, Mann K, Rietschel M.

Arch Gen Psychiatry. 2009 Jul;66(7):773-84. doi: 10.1001/archgenpsychiatry.2009.83.

20.

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.

Mbarek H, Milaneschi Y, Fedko IO, Hottenga JJ, de Moor MH, Jansen R, Gelernter J, Sherva R, Willemsen G, Boomsma DI, Penninx BW, Vink JM.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):739-48. doi: 10.1002/ajmg.b.32379. Epub 2015 Sep 14.

PMID:
26365420

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