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Items: 1 to 20 of 145


IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections.

Shepardson KM, Larson K, Johns LL, Stanek K, Cho H, Wellham J, Henderson H, Rynda-Apple A.

Front Immunol. 2018 Nov 9;9:2589. doi: 10.3389/fimmu.2018.02589. eCollection 2018.


Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection.

Shepardson KM, Larson K, Morton RV, Prigge JR, Schmidt EE, Huber VC, Rynda-Apple A.

MBio. 2016 May 3;7(3). pii: e00506-16. doi: 10.1128/mBio.00506-16.


A Novel Role for PDZ-Binding Motif of Influenza A Virus Nonstructural Protein 1 in Regulation of Host Susceptibility to Postinfluenza Bacterial Superinfections.

Shepardson K, Larson K, Cho H, Johns LL, Malkoc Z, Stanek K, Wellhman J, Zaiser S, Daggs-Olson J, Moodie T, Klonoski JM, Huber VC, Rynda-Apple A.

Viral Immunol. 2019 Apr;32(3):131-143. doi: 10.1089/vim.2018.0118. Epub 2019 Mar 1.


Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1.

Xia C, Vijayan M, Pritzl CJ, Fuchs SY, McDermott AB, Hahm B.

J Virol. 2015 Dec 16;90(5):2403-17. doi: 10.1128/JVI.02749-15.


Casein Kinase 1α Mediates the Degradation of Receptors for Type I and Type II Interferons Caused by Hemagglutinin of Influenza A Virus.

Xia C, Wolf JJ, Vijayan M, Studstill CJ, Ma W, Hahm B.

J Virol. 2018 Mar 14;92(7). pii: e00006-18. doi: 10.1128/JVI.00006-18. Print 2018 Apr 1.


Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice.

Lee B, Robinson KM, McHugh KJ, Scheller EV, Mandalapu S, Chen C, Di YP, Clay ME, Enelow RI, Dubin PJ, Alcorn JF.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L158-67. doi: 10.1152/ajplung.00338.2014. Epub 2015 May 22.


Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection.

Shirey KA, Perkins DJ, Lai W, Zhang W, Fernando LR, Gusovsky F, Blanco JCG, Vogel SN.

MBio. 2019 May 7;10(3). pii: e00810-19. doi: 10.1128/mBio.00810-19.


Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung.

Small CL, Shaler CR, McCormick S, Jeyanathan M, Damjanovic D, Brown EG, Arck P, Jordana M, Kaushic C, Ashkar AA, Xing Z.

J Immunol. 2010 Feb 15;184(4):2048-56. doi: 10.4049/jimmunol.0902772. Epub 2010 Jan 18.


Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation.

Stifter SA, Bhattacharyya N, Pillay R, Flórido M, Triccas JA, Britton WJ, Feng CG.

PLoS Pathog. 2016 Jan 5;12(1):e1005378. doi: 10.1371/journal.ppat.1005378. eCollection 2016 Jan.


Increased susceptibility for superinfection with Streptococcus pneumoniae during influenza virus infection is not caused by TLR7-mediated lymphopenia.

Stegemann S, Dahlberg S, Kröger A, Gereke M, Bruder D, Henriques-Normark B, Gunzer M.

PLoS One. 2009;4(3):e4840. doi: 10.1371/journal.pone.0004840. Epub 2009 Mar 17.


Interferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses.

Mordstein M, Kochs G, Dumoutier L, Renauld JC, Paludan SR, Klucher K, Staeheli P.

PLoS Pathog. 2008 Sep 12;4(9):e1000151. doi: 10.1371/journal.ppat.1000151.


Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection.

Beshara R, Sencio V, Soulard D, Barthélémy A, Fontaine J, Pinteau T, Deruyter L, Ismail MB, Paget C, Sirard JC, Trottein F, Faveeuw C.

PLoS Pathog. 2018 Oct 29;14(10):e1007360. doi: 10.1371/journal.ppat.1007360. eCollection 2018 Oct.


Regulation of IFN-γ by IL-13 dictates susceptibility to secondary postinfluenza MRSA pneumonia.

Rynda-Apple A, Harmsen A, Erickson AS, Larson K, Morton RV, Richert LE, Harmsen AG.

Eur J Immunol. 2014 Nov;44(11):3263-72. doi: 10.1002/eji.201444582. Epub 2014 Sep 1.


Novel protective mechanism for interleukin-33 at the mucosal barrier during influenza-associated bacterial superinfection.

Robinson KM, Ramanan K, Clay ME, McHugh KJ, Rich HE, Alcorn JF.

Mucosal Immunol. 2018 Jan;11(1):199-208. doi: 10.1038/mi.2017.32. Epub 2017 Apr 12.


The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice.

Price GE, Gaszewska-Mastarlarz A, Moskophidis D.

J Virol. 2000 May;74(9):3996-4003.


Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection.

Planet PJ, Parker D, Cohen TS, Smith H, Leon JD, Ryan C, Hammer TJ, Fierer N, Chen EI, Prince AS.

MBio. 2016 Feb 9;7(1):e01939-15. doi: 10.1128/mBio.01939-15.


The role of IL-27 in susceptibility to post-influenza Staphylococcus aureus pneumonia.

Robinson KM, Lee B, Scheller EV, Mandalapu S, Enelow RI, Kolls JK, Alcorn JF.

Respir Res. 2015 Feb 5;16:10. doi: 10.1186/s12931-015-0168-8.


Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice.

Kudva A, Scheller EV, Robinson KM, Crowe CR, Choi SM, Slight SR, Khader SA, Dubin PJ, Enelow RI, Kolls JK, Alcorn JF.

J Immunol. 2011 Feb 1;186(3):1666-1674. doi: 10.4049/jimmunol.1002194. Epub 2010 Dec 22.


Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection.

Kroetz DN, Allen RM, Schaller MA, Cavallaro C, Ito T, Kunkel SL.

PLoS Pathog. 2015 Dec 28;11(12):e1005338. doi: 10.1371/journal.ppat.1005338. eCollection 2015 Dec.


Influenza A virus-induced release of interleukin-10 inhibits the anti-microbial activities of invariant natural killer T cells during invasive pneumococcal superinfection.

Barthelemy A, Ivanov S, Fontaine J, Soulard D, Bouabe H, Paget C, Faveeuw C, Trottein F.

Mucosal Immunol. 2017 Mar;10(2):460-469. doi: 10.1038/mi.2016.49. Epub 2016 May 25.


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