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Items: 1 to 20 of 121

1.

NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.

Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, Ganguly S, Lan T, Karin M, Kisseleva T, Brenner DA.

Gastroenterology. 2019 Mar;156(4):1156-1172.e6. doi: 10.1053/j.gastro.2018.11.019. Epub 2018 Nov 13.

2.

Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.

Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B.

J Cell Physiol. 2018 Jun;233(6):5002-5013. doi: 10.1002/jcp.26349. Epub 2018 Jan 4.

PMID:
29227538
3.

Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.

Sun L, Beggs K, Borude P, Edwards G, Bhushan B, Walesky C, Roy N, Manley MW Jr, Gunewardena S, O'Neil M, Li H, Apte U.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G91-G104. doi: 10.1152/ajpgi.00027.2015. Epub 2016 May 5.

4.
5.

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence.

Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F.

Gastroenterology. 2019 May;156(6):1877-1889.e4. doi: 10.1053/j.gastro.2019.01.247. Epub 2019 Jan 30.

PMID:
30710528
6.

Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis.

Chen L, Lu X, Zeng T, Chen Y, Chen Q, Wu W, Yan X, Cai H, Zhang Z, Shao Q, Qin W.

Oncol Rep. 2014 Feb;31(2):885-93. doi: 10.3892/or.2013.2908. Epub 2013 Dec 6.

PMID:
24337404
7.

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.

Aoyama T, Paik YH, Watanabe S, Laleu B, Gaggini F, Fioraso-Cartier L, Molango S, Heitz F, Merlot C, Szyndralewiez C, Page P, Brenner DA.

Hepatology. 2012 Dec;56(6):2316-27. doi: 10.1002/hep.25938.

8.

Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.

Wree A, Johnson CD, Font-Burgada J, Eguchi A, Povero D, Karin M, Feldstein AE.

Cell Death Differ. 2015 Dec;22(12):1985-94. doi: 10.1038/cdd.2015.46. Epub 2015 Apr 24.

9.

Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease.

Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Szabo G.

World J Gastroenterol. 2016 Apr 28;22(16):4091-108. doi: 10.3748/wjg.v22.i16.4091.

10.

Superoxide deficiency attenuates promotion of hepatocarcinogenesis by cytotoxicity in NADPH oxidase knockout mice.

Parzefall W, Freiler C, Lorenz O, Koudelka H, Riegler T, Nejabat M, Kainzbauer E, Grasl-Kraupp B, Schulte-Hermann R.

Arch Toxicol. 2015 Aug;89(8):1383-93. doi: 10.1007/s00204-014-1298-3. Epub 2014 Sep 3.

PMID:
25182417
11.

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

Teufelhofer O, Parzefall W, Kainzbauer E, Ferk F, Freiler C, Knasmüller S, Elbling L, Thurman R, Schulte-Hermann R.

Carcinogenesis. 2005 Feb;26(2):319-29. Epub 2004 Oct 28.

PMID:
15513930
12.

TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver.

Weber SN, Bohner A, Dapito DH, Schwabe RF, Lammert F.

PLoS One. 2016 Jul 8;11(7):e0158819. doi: 10.1371/journal.pone.0158819. eCollection 2016.

13.

Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer.

Schneider C, Teufel A, Yevsa T, Staib F, Hohmeyer A, Walenda G, Zimmermann HW, Vucur M, Huss S, Gassler N, Wasmuth HE, Lira SA, Zender L, Luedde T, Trautwein C, Tacke F.

Gut. 2012 Dec;61(12):1733-43. doi: 10.1136/gutjnl-2011-301116. Epub 2012 Jan 20.

14.

G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis.

Wei T, Chen W, Wen L, Zhang J, Zhang Q, Yang J, Liu H, Chen BW, Zhou Y, Feng X, Yang Q, Bai X, Liang T.

Cancer Lett. 2016 Nov 28;382(2):195-202. doi: 10.1016/j.canlet.2016.08.012. Epub 2016 Sep 1.

PMID:
27594673
15.

Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model.

Chen N, Nishio N, Ito S, Tanaka Y, Sun Y, Isobe K.

Cancer Immunol Immunother. 2015 Jun;64(6):777-89. doi: 10.1007/s00262-015-1690-8. Epub 2015 Apr 2.

PMID:
25832002
16.

Cell expression patterns of CD147 in N-diethylnitrosamine/phenobarbital-induced mouse hepatocellular carcinoma.

Lu M, Wu J, He F, Wang XL, Li C, Chen ZN, Bian H.

J Mol Histol. 2015 Feb;46(1):79-91. doi: 10.1007/s10735-014-9602-3. Epub 2014 Dec 2.

PMID:
25447507
17.

High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma.

Duan XY, Pan Q, Yan SY, Ding WJ, Fan JG, Qiao L.

BMC Gastroenterol. 2014 Nov 20;14:195. doi: 10.1186/s12876-014-0195-9.

18.

Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.

Lan T, Kisseleva T, Brenner DA.

PLoS One. 2015 Jul 29;10(7):e0129743. doi: 10.1371/journal.pone.0129743. eCollection 2015.

19.

The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis.

Shibata Y, Hara T, Nagano J, Nakamura N, Ohno T, Ninomiya S, Ito H, Tanaka T, Saito K, Seishima M, Shimizu M, Moriwaki H, Tsurumi H.

PLoS One. 2016 Jan 4;11(1):e0146279. doi: 10.1371/journal.pone.0146279. eCollection 2016.

20.

Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.

Wang J, Zhao J, Chu ES, Mok MT, Go MY, Man K, Heuchel R, Lan HY, Chang Z, Sung JJ, Yu J.

J Pathol. 2013 Aug;230(4):441-52. doi: 10.1002/path.4206.

PMID:
23625826

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