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Items: 1 to 20 of 103

1.

PIK3IP1/TrIP restricts activation of T cells through inhibition of PI3K/Akt.

Uche UU, Piccirillo AR, Kataoka S, Grebinoski SJ, D'Cruz LM, Kane LP.

J Exp Med. 2018 Dec 3;215(12):3165-3179. doi: 10.1084/jem.20172018. Epub 2018 Nov 14.

2.

ETP-46321, a dual p110α/δ class IA phosphoinositide 3-kinase inhibitor modulates T lymphocyte activation and collagen-induced arthritis.

Aragoneses-Fenoll L, Montes-Casado M, Ojeda G, Acosta YY, Herranz J, Martínez S, Blanco-Aparicio C, Criado G, Pastor J, Dianzani U, Portolés P, Rojo JM.

Biochem Pharmacol. 2016 Apr 15;106:56-69. doi: 10.1016/j.bcp.2016.02.005. Epub 2016 Feb 13.

3.

B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation.

Singh MD, Ni M, Sullivan JM, Hamerman JA, Campbell DJ.

J Exp Med. 2018 Sep 3;215(9):2429-2443. doi: 10.1084/jem.20171820. Epub 2018 Aug 9.

4.

Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.

Chapman NM, Yoder AN, Barbón KM, Bilal MY, Connolly SF, Houtman JC.

J Leukoc Biol. 2015 Feb;97(2):285-96. doi: 10.1189/jlb.2A1013-568RRR. Epub 2014 Nov 11.

5.

Activation of PI3K/Akt signaling by n-terminal SH2 domain mutants of the p85α regulatory subunit of PI3K is enhanced by deletion of its c-terminal SH2 domain.

Hofmann BT, Jücker M.

Cell Signal. 2012 Oct;24(10):1950-4. doi: 10.1016/j.cellsig.2012.06.009. Epub 2012 Jun 24.

PMID:
22735814
6.
7.

Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection.

Telieps T, Ewald F, Gereke M, Annemann M, Rauter Y, Schuster M, Ueffing N, von Smolinski D, Gruber AD, Bruder D, Schmitz I.

Eur J Immunol. 2013 Jun;43(6):1499-510. doi: 10.1002/eji.201242819. Epub 2013 May 2.

8.

Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway.

Song HK, Kim J, Lee JS, Nho KJ, Jeong HC, Kim J, Ahn Y, Park WJ, Kim DH.

PLoS One. 2015 Mar 31;10(3):e0122251. doi: 10.1371/journal.pone.0122251. eCollection 2015.

9.

The Role of p110δ in the Development and Activation of B Lymphocytes.

Newman R, Turner M.

Adv Exp Med Biol. 2015;850:119-35. doi: 10.1007/978-3-319-15774-0_9. Review.

PMID:
26324350
10.

Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85alpha Src homology-2 domains.

Lee JY, Chiu YH, Asara J, Cantley LC.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14157-62. doi: 10.1073/pnas.1107747108. Epub 2011 Aug 8.

11.

Nonconventional CD8+ T cell responses to Listeria infection in mice lacking MHC class Ia and H2-M3.

Cho H, Choi HJ, Xu H, Felio K, Wang CR.

J Immunol. 2011 Jan 1;186(1):489-98. doi: 10.4049/jimmunol.1002639. Epub 2010 Nov 22.

12.

Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation.

de la Cruz-Herrera CF, Baz-Martínez M, Lang V, El Motiam A, Barbazán J, Couceiro R, Abal M, Vidal A, Esteban M, Muñoz-Fontela C, Nieto A, Rodríguez MS, Collado M, Rivas C.

Oncogene. 2016 Jun 2;35(22):2873-80. doi: 10.1038/onc.2015.356. Epub 2015 Sep 28.

PMID:
26411363
13.

Inhibition of T-cell activation by PIK3IP1.

DeFrances MC, Debelius DR, Cheng J, Kane LP.

Eur J Immunol. 2012 Oct;42(10):2754-9. doi: 10.1002/eji.201141653. Epub 2012 Jul 19.

14.

Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit.

Neal CL, Xu J, Li P, Mori S, Yang J, Neal NN, Zhou X, Wyszomierski SL, Yu D.

Oncogene. 2012 Feb 16;31(7):897-906. doi: 10.1038/onc.2011.284. Epub 2011 Jul 11.

15.
16.

PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein.

Zhu Z, He X, Johnson C, Stoops J, Eaker AE, Stoffer DS, Bell A, Zarnegar R, DeFrances MC.

Biochem Biophys Res Commun. 2007 Jun 22;358(1):66-72. Epub 2007 Apr 24.

17.

T cell recognition of listeriolysin O is induced during infection with Listeria monocytogenes.

Berche P, Gaillard JL, Geoffroy C, Alouf JE.

J Immunol. 1987 Dec 1;139(11):3813-21.

PMID:
3119720
18.
19.

Nonhematopoietic cells control the outcome of infection with Listeria monocytogenes in a nucleotide oligomerization domain 1-dependent manner.

Mosa A, Trumstedt C, Eriksson E, Soehnlein O, Heuts F, Janik K, Klos A, Dittrich-Breiholz O, Kracht M, Hidmark A, Wigzell H, Rottenberg ME.

Infect Immun. 2009 Jul;77(7):2908-18. doi: 10.1128/IAI.01068-08. Epub 2009 Apr 27.

20.

CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection.

Côme C, Cvrljevic A, Khan MM, Treise I, Adler T, Aguilar-Pimentel JA, Au-Yeung B, Sittig E, Laajala TD, Chen Y, Oeder S, Calzada-Wack J, Horsch M, Aittokallio T, Busch DH, Ollert MW, Neff F, Beckers J, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Chen Z, Lahesmaa R, Westermarck J.

PLoS One. 2016 Apr 21;11(4):e0152996. doi: 10.1371/journal.pone.0152996. eCollection 2016.

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