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Items: 1 to 20 of 100

1.

Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model.

Miller SJ, Glatzer JC, Hsieh YC, Rothstein JD.

J Neurogenet. 2018 Dec;32(4):322-335. doi: 10.1080/01677063.2018.1513508. Epub 2018 Nov 6.

PMID:
30398075
2.

Astroglial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model.

Miller SJ, Zhang PW, Glatzer J, Rothstein JD.

J Neurogenet. 2017 Mar - Jun;31(1-2):37-48. doi: 10.1080/01677063.2016.1260128. Epub 2016 Dec 25.

PMID:
28019127
3.

Regional differences in the inflammatory and heat shock response in glia: implications for ALS.

Clarke BE, Gil RS, Yip J, Kalmar B, Greensmith L.

Cell Stress Chaperones. 2019 Jun 5. doi: 10.1007/s12192-019-01005-y. [Epub ahead of print]

PMID:
31168740
4.

RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.

Vallarola A, Sironi F, Tortarolo M, Gatto N, De Gioia R, Pasetto L, De Paola M, Mariani A, Ghosh S, Watson R, Kalmes A, Bonetto V, Bendotti C.

J Neuroinflammation. 2018 Mar 1;15(1):65. doi: 10.1186/s12974-018-1101-0.

5.

Histamine Regulates the Inflammatory Profile of SOD1-G93A Microglia and the Histaminergic System Is Dysregulated in Amyotrophic Lateral Sclerosis.

Apolloni S, Fabbrizio P, Amadio S, Napoli G, Verdile V, Morello G, Iemmolo R, Aronica E, Cavallaro S, Volonté C.

Front Immunol. 2017 Nov 30;8:1689. doi: 10.3389/fimmu.2017.01689. eCollection 2017.

6.

Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis.

Tury A, Tolentino K, Zou Y.

Dev Neurobiol. 2014 Aug;74(8):839-50. doi: 10.1002/dneu.22137. Epub 2014 Jan 22. Review.

7.

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.

Almad AA, Doreswamy A, Gross SK, Richard JP, Huo Y, Haughey N, Maragakis NJ.

Glia. 2016 Jul;64(7):1154-69. doi: 10.1002/glia.22989. Epub 2016 Apr 16.

8.
9.

GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.

Li K, Hala TJ, Seetharam S, Poulsen DJ, Wright MC, Lepore AC.

Neurobiol Dis. 2015 Jun;78:12-23. doi: 10.1016/j.nbd.2015.03.010. Epub 2015 Mar 25.

PMID:
25818008
10.

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.

Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C.

Brain. 2013 Nov;136(Pt 11):3305-32. doi: 10.1093/brain/awt250. Epub 2013 Sep 24.

PMID:
24065725
11.

Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G⁹³A transgenic ALS mice.

Ozdinler PH, Benn S, Yamamoto TH, Güzel M, Brown RH Jr, Macklis JD.

J Neurosci. 2011 Mar 16;31(11):4166-77. doi: 10.1523/JNEUROSCI.4184-10.2011.

12.

Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Milanese M, Giribaldi F, Melone M, Bonifacino T, Musante I, Carminati E, Rossi PI, Vergani L, Voci A, Conti F, Puliti A, Bonanno G.

Neurobiol Dis. 2014 Apr;64:48-59. doi: 10.1016/j.nbd.2013.11.006. Epub 2013 Dec 19.

13.

Characterizing the multiple roles of FGF-2 in SOD1G93A ALS mice in vivo and in vitro.

Kefalakes E, Böselt S, Sarikidi A, Ettcheto M, Bursch F, Naujock M, Stanslowsky N, Schmuck M, Barenys M, Wegner F, Grothe C, Petri S.

J Cell Physiol. 2019 May;234(5):7395-7410. doi: 10.1002/jcp.27498. Epub 2018 Oct 28.

PMID:
30370540
14.

In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

Bonifacino T, Cattaneo L, Gallia E, Puliti A, Melone M, Provenzano F, Bossi S, Musante I, Usai C, Conti F, Bonanno G, Milanese M.

Neuropharmacology. 2017 Sep 1;123:433-445. doi: 10.1016/j.neuropharm.2017.06.020. Epub 2017 Jun 21.

PMID:
28645622
15.

Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.

Fellner A, Barhum Y, Angel A, Perets N, Steiner I, Offen D, Lev N.

Int J Mol Sci. 2017 Aug 1;18(8). pii: E1666. doi: 10.3390/ijms18081666.

16.

CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1.

Silverman JM, Christy D, Shyu CC, Moon KM, Fernando S, Gidden Z, Cowan CM, Ban Y, Stacey RG, Grad LI, McAlary L, Mackenzie IR, Foster LJ, Cashman NR.

J Biol Chem. 2019 Mar 8;294(10):3744-3759. doi: 10.1074/jbc.RA118.004825. Epub 2019 Jan 11.

PMID:
30635404
17.

Mechanisms of Enhanced Phrenic Long-Term Facilitation in SOD1G93A Rats.

Nichols NL, Satriotomo I, Allen LL, Grebe AM, Mitchell GS.

J Neurosci. 2017 Jun 14;37(24):5834-5845. doi: 10.1523/JNEUROSCI.3680-16.2017. Epub 2017 May 12.

18.

Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.

Apolloni S, Fabbrizio P, Amadio S, Volonté C.

J Neuroinflammation. 2016 Aug 22;13(1):191. doi: 10.1186/s12974-016-0658-8.

19.

Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.

Jiang HQ, Ren M, Jiang HZ, Wang J, Zhang J, Yin X, Wang SY, Qi Y, Wang XD, Feng HL.

Neuroscience. 2014 Sep 26;277:132-8. doi: 10.1016/j.neuroscience.2014.03.047. Epub 2014 Mar 31.

PMID:
24699224
20.

PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Ringer C, Büning LS, Schäfer MK, Eiden LE, Weihe E, Schütz B.

Neurobiol Dis. 2013 Jun;54:32-42. doi: 10.1016/j.nbd.2013.02.010. Epub 2013 Mar 4.

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