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Items: 1 to 20 of 103


Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats.

Fong LY, Jing R, Smalley KJ, Wang ZX, Taccioli C, Fan S, Chen H, Alder H, Huebner K, Farber JL, Fiehn O, Croce CM.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11091-E11100. doi: 10.1073/pnas.1813956115. Epub 2018 Nov 5.


Human prostate cancer ZIP1/zinc/citrate genetic/metabolic relationship in the TRAMP prostate cancer animal model.

Costello LC, Franklin RB, Zou J, Feng P, Bok R, Swanson MG, Kurhanewicz J.

Cancer Biol Ther. 2011 Dec 15;12(12):1078-84. doi: 10.4161/cbt.12.12.18367. Epub 2011 Dec 15.


hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer.

Franklin RB, Feng P, Milon B, Desouki MM, Singh KK, Kajdacsy-Balla A, Bagasra O, Costello LC.

Mol Cancer. 2005 Sep 9;4:32.


hZIP1 zinc transporter down-regulation in prostate cancer involves the overexpression of ras responsive element binding protein-1 (RREB-1).

Zou J, Milon BC, Desouki MM, Costello LC, Franklin RB.

Prostate. 2011 Oct 1;71(14):1518-24. doi: 10.1002/pros.21368. Epub 2011 Feb 25.


hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands.

Desouki MM, Geradts J, Milon B, Franklin RB, Costello LC.

Mol Cancer. 2007 Jun 5;6:37.


Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo.

Taccioli C, Garofalo M, Chen H, Jiang Y, Tagliazucchi GM, Di Leva G, Alder H, Fadda P, Middleton J, Smalley KJ, Selmi T, Naidu S, Farber JL, Croce CM, Fong LY.

J Natl Cancer Inst. 2015 Aug 18;107(11). pii: djv220. doi: 10.1093/jnci/djv220. Print 2015 Nov.


Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia.

Fong LY, Jing R, Smalley KJ, Taccioli C, Fahrmann J, Barupal DK, Alder H, Farber JL, Fiehn O, Croce CM.

Oncotarget. 2017 Jun 9;8(47):81910-81925. doi: 10.18632/oncotarget.18434. eCollection 2017 Oct 10.


The miR-183 family cluster alters zinc homeostasis in benign prostate cells, organoids and prostate cancer xenografts.

Dambal S, Baumann B, McCray T, Williams L, Richards Z, Deaton R, Prins GS, Nonn L.

Sci Rep. 2017 Aug 9;7(1):7704. doi: 10.1038/s41598-017-07979-y.


miR-34c is downregulated in prostate cancer and exerts tumor suppressive functions.

Hagman Z, Larne O, Edsjö A, Bjartell A, Ehrnström RA, Ulmert D, Lilja H, Ceder Y.

Int J Cancer. 2010 Dec 15;127(12):2768-76. doi: 10.1002/ijc.25269.


Differential expression of metallothioneins (MTs) 1, 2, and 3 in response to zinc treatment in human prostate normal and malignant cells and tissues.

Wei H, Desouki MM, Lin S, Xiao D, Franklin RB, Feng P.

Mol Cancer. 2008 Jan 21;7:7. doi: 10.1186/1476-4598-7-7.


Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.

Henrique R, Costa VL, Cerveira N, Carvalho AL, Hoque MO, Ribeiro FR, Oliveira J, Teixeira MR, Sidransky D, Jerónimo C.

J Mol Med (Berl). 2006 Nov;84(11):911-8. Epub 2006 Sep 22.


Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues.

Singh KK, Desouki MM, Franklin RB, Costello LC.

Mol Cancer. 2006 Apr 4;5:14.


Up-regulation of TRPM-2, MMP-7 and ID-1 during sex hormone-induced prostate carcinogenesis in the Noble rat.

Ouyang XS, Wang X, Lee DT, Tsao SW, Wong YC.

Carcinogenesis. 2001 Jun;22(6):965-73.


Tissue-specific alterations in zinc transporter expression in intestine and liver reflect a threshold for homeostatic compensation during dietary zinc deficiency in weanling rats.

Jou MY, Hall AG, Philipps AF, Kelleher SL, Lönnerdal B.

J Nutr. 2009 May;139(5):835-41. doi: 10.3945/jn.108.100974. Epub 2009 Mar 18.


MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency.

Fong LY, Taccioli C, Jing R, Smalley KJ, Alder H, Jiang Y, Fadda P, Farber JL, Croce CM.

Oncotarget. 2016 Mar 8;7(10):10723-38. doi: 10.18632/oncotarget.7561.


Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis.

Song H, Zhang B, Watson MA, Humphrey PA, Lim H, Milbrandt J.

Oncogene. 2009 Sep 17;28(37):3307-19. doi: 10.1038/onc.2009.181. Epub 2009 Jul 13.


A regulatory circuit HP1γ/miR-451a/c-Myc promotes prostate cancer progression.

Chang C, Liu J, He W, Qu M, Huang X, Deng Y, Shen L, Zhao X, Guo H, Jiang J, Fu XY, Huang R, Zhang D, Yan J.

Oncogene. 2018 Jan 25;37(4):415-426. doi: 10.1038/onc.2017.332. Epub 2017 Oct 2.


miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells.

Mihelich BL, Khramtsova EA, Arva N, Vaishnav A, Johnson DN, Giangreco AA, Martens-Uzunova E, Bagasra O, Kajdacsy-Balla A, Nonn L.

J Biol Chem. 2011 Dec 30;286(52):44503-11. doi: 10.1074/jbc.M111.262915. Epub 2011 Nov 1.


Magnesium and calcium deficiencies additively increase zinc concentrations and metallothionein expression in the rat liver.

Kotani M, Kim KH, Ishizaki N, Funaba M, Matsui T.

Br J Nutr. 2013 Feb 14;109(3):425-32. doi: 10.1017/S0007114512001195. Epub 2012 May 9.


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