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Items: 1 to 20 of 101

1.

Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation.

Riva G, Cilibrasi C, Bazzoni R, Cadamuro M, Negroni C, Butta V, Strazzabosco M, Dalprà L, Lavitrano M, Bentivegna A.

Genes (Basel). 2018 Oct 26;9(11). pii: E522. doi: 10.3390/genes9110522.

2.

Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway.

Cilibrasi C, Riva G, Romano G, Cadamuro M, Bazzoni R, Butta V, Paoletta L, Dalprà L, Strazzabosco M, Lavitrano M, Giovannoni R, Bentivegna A.

PLoS One. 2017 Jan 12;12(1):e0169854. doi: 10.1371/journal.pone.0169854. eCollection 2017.

3.

Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.

Cattaneo M, Baronchelli S, Schiffer D, Mellai M, Caldera V, Saccani GJ, Dalpra L, Daga A, Orlandi R, DeBlasio P, Biunno I.

J Biol Chem. 2014 Jan 31;289(5):2826-38. doi: 10.1074/jbc.M113.527754. Epub 2013 Dec 5.

4.

Epigenetic targeting of glioma stem cells: Short-term and long-term treatments with valproic acid modulate DNA methylation and differentiation behavior, but not temozolomide sensitivity.

Riva G, Butta V, Cilibrasi C, Baronchelli S, Redaelli S, Dalprà L, Lavitrano M, Bentivegna A.

Oncol Rep. 2016 May;35(5):2811-24. doi: 10.3892/or.2016.4665. Epub 2016 Mar 9.

PMID:
26986767
5.

Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia.

Shao N, Zou J, Li J, Chen F, Dai J, Qu X, Sun X, Ma D, Ji C.

Leuk Lymphoma. 2012 Sep;53(9):1769-78. doi: 10.3109/10428194.2012.663085. Epub 2012 Mar 13.

PMID:
22303878
6.

Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells.

Kim KH, Seol HJ, Kim EH, Rheey J, Jin HJ, Lee Y, Joo KM, Lee J, Nam DH.

Neuro Oncol. 2013 Feb;15(2):161-71. doi: 10.1093/neuonc/nos299. Epub 2012 Dec 20.

7.

PI3K inhibitor combined with miR-125b inhibitor sensitize TMZ-induced anti-glioma stem cancer effects through inactivation of Wnt/β-catenin signaling pathway.

Shi L, Fei X, Wang Z, You Y.

In Vitro Cell Dev Biol Anim. 2015 Nov;51(10):1047-55. doi: 10.1007/s11626-015-9931-x. Epub 2015 Jul 14.

PMID:
26170223
8.

Development of a novel neuroprotective strategy: combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells.

Jin G, Liu B, You Z, Bambakidis T, Dekker SE, Maxwell J, Halaweish I, Linzel D, Alam HB.

Surgery. 2014 Aug;156(2):221-8. doi: 10.1016/j.surg.2014.03.038. Epub 2014 Jun 18.

9.

IDH1 mutation diminishes aggressive phenotype in glioma stem cells.

Yao Q, Cai G, Yu Q, Shen J, Gu Z, Chen J, Shi W, Shi J.

Int J Oncol. 2018 Jan;52(1):270-278. doi: 10.3892/ijo.2017.4186. Epub 2017 Nov 3.

PMID:
29115585
10.

Valproate recovers the inhibitory effect of dexamethasone on the proliferation of the adult dentate gyrus-derived neural precursor cells via GSK-3β and β-catenin pathway.

Boku S, Nakagawa S, Masuda T, Nishikawa H, Kato A, Takamura N, Omiya Y, Kitaichi Y, Inoue T, Kusumi I.

Eur J Pharmacol. 2014 Jan 15;723:425-30. doi: 10.1016/j.ejphar.2013.10.060. Epub 2013 Nov 7.

PMID:
24211784
11.

Wnt signaling pathway participates in valproic acid-induced neuronal differentiation of neural stem cells.

Wang L, Liu Y, Li S, Long ZY, Wu YM.

Int J Clin Exp Pathol. 2015 Jan 1;8(1):578-85. eCollection 2015.

12.

Metallothionein 1H (MT1H) functions as a tumor suppressor in hepatocellular carcinoma through regulating Wnt/β-catenin signaling pathway.

Zheng Y, Jiang L, Hu Y, Xiao C, Xu N, Zhou J, Zhou X.

BMC Cancer. 2017 Feb 28;17(1):161. doi: 10.1186/s12885-017-3139-2.

13.

miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase.

Wang K, Wang X, Zou J, Zhang A, Wan Y, Pu P, Song Z, Qian C, Chen Y, Yang S, Wang Y.

Neuro Oncol. 2013 May;15(5):578-88. doi: 10.1093/neuonc/not004. Epub 2013 Feb 14. Erratum in: Neuro Oncol. 2013 Jul;15(7):970.

14.

Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells.

Colella B, Faienza F, Carinci M, D'Alessandro G, Catalano M, Santoro A, Cecconi F, Limatola C, Di Bartolomeo S.

Cell Signal. 2019 Jan;53:357-364. doi: 10.1016/j.cellsig.2018.10.017. Epub 2018 Oct 26.

PMID:
30442596
15.

Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation.

Kierulf-Vieira KS, Sandberg CJ, Grieg Z, Günther CC, Langmoen IA, Vik-Mo EO.

Exp Cell Res. 2016 Jan 1;340(1):53-61. doi: 10.1016/j.yexcr.2015.12.010. Epub 2015 Dec 19.

16.

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway.

Liu QQ, Chen K, Ye Q, Jiang XH, Sun YW.

Cancer Cell Int. 2016 Jul 22;16:57. doi: 10.1186/s12935-016-0336-z. eCollection 2016.

17.

Histone deacetylase inhibitor, valproic acid, radiosensitizes the C6 glioma cell line in vitro.

Zhou Y, Xu Y, Wang H, Niu J, Hou H, Jiang Y.

Oncol Lett. 2014 Jan;7(1):203-208. Epub 2013 Nov 7.

19.

Wnt/β-catenin pathway involvement in ionizing radiation-induced invasion of U87 glioblastoma cells.

Dong Z, Zhou L, Han N, Zhang M, Lyu X.

Strahlenther Onkol. 2015 Aug;191(8):672-80. doi: 10.1007/s00066-015-0858-7. Epub 2015 Jun 14.

PMID:
26072169
20.

Pioglitazone Effect on Glioma Stem Cell Lines: Really a Promising Drug Therapy for Glioblastoma?

Cilibrasi C, Butta V, Riva G, Bentivegna A.

PPAR Res. 2016;2016:7175067. doi: 10.1155/2016/7175067. Epub 2016 May 25.

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