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30359321,27005844,31159888,28420436,24670364,22833529,26177266,31918758,26902855,30896831,22435530,29183009,31960418,30989714,35090551,32522253,28848091,25759412,28260056,30335903,30550853,26668506,22356678,29608885,23386286,24847908,28708244,25896286,25986930,16598383,29947256,26499488,30835892,33605598,22698588,30616426,28581448,30635025,31468266,32544529,20819633,26800376,34815829,30613290,30359325,16563361,30367841,33164579,27025401,30970221,27103465,31578787,28367092,28901391,33298178,19997978,26584290,30391592,24604717,25562170,31927699,29705776,29705604,31959090,24021916,29921652,35610401,23885779,26139607,28412246,29360689,28457660,30953350,30448444,29027451,26487273,30025493,29178928,25871970,31660694,25816157,29404727,30923227,24598112,26379190,26202359,29725013,30305185,32468683,27417237,29111231,23743762,16581974,34242625,19489098,26847932,25288154,30566395,34294127,18948617,31759056,33317626,28198521,29148068,21610320,17478584,29961786,24367027,18199451,30257237,28825154,28173835,22886775,29533930,22186034,24797554,30409193,23538444,27029904,24448905,30880031,28284757,27363263,29788929,17497701,33174056,33951411,18308163,29048631,30324847,31589902,29451335,32459063,30136033,23697984,23683277,31296837,31368195,22282242,25996292,31881006,27906055,28662151,26607398,28233339,31194992,29752623,26246196,35091805,23419688,30213506,32271805,27228350,31036073,21593791,19691857,24447518,32581152,31050281,19414636,31200719,29724989,30279567,22222116,31582727,32003536,31398416,32634329,31550244,24905997,30528392,28860574,19816949,31679117,26919192,20154257,20041970,24599264,32003125,33323934,21733181,19353525,31332165,30635041,22785211,31142342,26496360,21321153,28425576,34898367,30463909,29078802,34093853,19639489,30926681,34494222,28978553,24635859,30404729,22729283,30365934,32196916,32879255,30703123,23817226,34051241,19509289,30720220,36333298,34674708,28726275,34768788,32959405,29722562,31378912,22913590,18511601,27551443,21786367,32432372,30486861,32229166,21606086,32424968,31783925,21463175,30549184,33535594,32927859,29050671,31020644,31971825,23763837,32757698,32216819,21233455,33788710,23558089,25216025,26546832,30642198,29328494,21992089,31135122,29216630,36627546,26784440,33355751,21585237,35507744,17056665,30980109,31553625,35265261,19218529,25117440,28894133,21673516,30104096,25157976,22658491,30464457,32372246,24628978,29141446,29996120,29655989,30458313,30235443,29652546,32685014,31654225,30683918,29158523,33627630,32767741,31173218,26466964,24989835,29718531,30242894,31054183,31992313,32713334,32952863,28216157,24781370,26035532,31025371,33050736,31463993,24471788,21671800,19507001,29540747,23333872,33546760,29258676,29904949,28647611,33769916,31325707,27565660,31512556,28559999,29575026,31755894,24669277,20861473,32475084,30864731,22573330,34520334,19780871,29748581,32515551,30452922,34935702,32284967,31210321,19652370,21957230,24942913,35931242,18763313,21846180,25158693,36416502,33279679,29278309,29665934,20446810,24551161,18819256,24022988,25315017,32908815,30359296,34080649,23695157,31508820,32569781,20736064,21562308,33076330,36618489,31178962,31180558,16603697,35264108,29921412,30097061,29138357,31185790,30538216,34852207,29315990,27748507,33507476,27145179,29999479,31228582,29518770,31638187,19721136,23681233,31383843,21681612,29510402,21678074,29265525,31753006,33895973,33483906,31298404,31985274,30296594,23606170,32966545,30883989,31964470,19411826,23443132,25485704,20455866,21200018,31672605,24827071,26319110,34339727,30927382,30664152,28422956,24583397,31358051,33146448,32772806,30814673,31969065,24748323,23305078,33050988,28600513,29627677,29904927,31032949,30658864,34374467,29329593,30706629,29744879,26899739,24680661,21245851,23536905,30257708,29500342,31675454,21698117,21244679,32061773,30398391,27199111,26081285,31018830,20678571,29384527,33452710,35051777,34390328,33513084,30597174,32348838,15297308,33206581,33257596,30756206,25693923,19883517,33906602,24202649,33628093,31535281,31678238,17483296,31036323,28987875,32656623,36747448,36464324,25324684,30897864,16942488,30738861,34572126,29724992,26422646,31443687,21477220,33450223,27807322,27800610,21493893,31066045,22135164,23388440,30911955,29993187,23082760,26017061,30887674,32706077,21472453,24201812,35385370,33113811,17224629,31100425,35752272,28468095,30455420,30260707,31892273,36052438,35066094,33257193,20826809,21421825,31158467,33786874,28349330,31090492,31926917,33829695,29858017,25060909,31969696,33567991,35186488,31769473,24042188,32235006,21307249,32729002,31524224,26962868,26344480,23804751,32839922,18663428,31081524,21959510,31611063,23826413,30227120,26157777,30076722,29797574,22523757,24727733,32148653,31678171,36652739,34321079,31115537,23963647,33042285,23706645,36852325,28456145,29257336,25145631,31771642,29556355,31875084,35219346,19580402,33416139,23951359,31262977,18849336,24480247,33435991,18616694,36244321,29517849,35157362,24338347,30317574,34774548,20833962,29730892,20626525,23409729,34432732,30254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Knockdown of insulin-like growth factor 1 exerts a protective effect on hypoxic injury of aged BM-MSCs: role of autophagy.

Yang M, Wen T, Chen H, Deng J, Yang C, Zhang Z. Yang M, et al. Stem Cell Res Ther. 2018 Oct 25;9(1):284. doi: 10.1186/s13287-018-1028-5. Stem Cell Res Ther. 2018. PMID: 30359321 Free PMC article.

Autophagy regulates the apoptosis of bone marrow-derived mesenchymal stem cells under hypoxic condition via AMP-activated protein kinase/mammalian target of rapamycin pathway.

Zhang Z, Yang M, Wang Y, Wang L, Jin Z, Ding L, Zhang L, Zhang L, Jiang W, Gao G, Yang J, Lu B, Cao F, Hu T. Zhang Z, et al. Cell Biol Int. 2016 Jun;40(6):671-85. doi: 10.1002/cbin.10604. Epub 2016 Apr 13. Cell Biol Int. 2016. PMID: 27005844

Inositol pyrophosphates mediated the apoptosis induced by hypoxic injury in bone marrow-derived mesenchymal stem cells by autophagy.

Deng J, Yang C, Wang Y, Yang M, Chen H, Ning H, Wang C, Liu Y, Zhang Z, Hu T. Deng J, et al. Stem Cell Res Ther. 2019 Jun 3;10(1):159. doi: 10.1186/s13287-019-1256-3. Stem Cell Res Ther. 2019. PMID: 31159888 Free PMC article.

Autophagy mediates the beneficial effect of hypoxic preconditioning on bone marrow mesenchymal stem cells for the therapy of myocardial infarction.

Zhang Z, Yang C, Shen M, Yang M, Jin Z, Ding L, Jiang W, Yang J, Chen H, Cao F, Hu T. Zhang Z, et al. Stem Cell Res Ther. 2017 Apr 18;8(1):89. doi: 10.1186/s13287-017-0543-0. Stem Cell Res Ther. 2017. PMID: 28420436 Free PMC article.

Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling.

Zhang Z, Zhao C, Liu B, Liang D, Qin X, Li X, Zhang R, Li C, Wang H, Sun D, Cao F. Zhang Z, et al. Stem Cell Res Ther. 2014 Mar 26;5(2):33. doi: 10.1186/scrt431. Stem Cell Res Ther. 2014. PMID: 24670364 Free PMC article.

Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR.

Lee Y, Jung J, Cho KJ, Lee SK, Park JW, Oh IH, Kim GJ. Lee Y, et al. J Cell Biochem. 2013 Jan;114(1):79-88. doi: 10.1002/jcb.24303. J Cell Biochem. 2013. PMID: 22833529

Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury.

Li J, Zhou J, Zhang D, Song Y, She J, Bai C. Li J, et al. J Cell Mol Med. 2015 Oct;19(10):2341-51. doi: 10.1111/jcmm.12638. Epub 2015 Jul 14. J Cell Mol Med. 2015. PMID: 26177266 Free PMC article.

IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway.

Lin M, Liu X, Zheng H, Huang X, Wu Y, Huang A, Zhu H, Hu Y, Mai W, Huang Y. Lin M, et al. Stem Cell Res Ther. 2020 Jan 9;11(1):22. doi: 10.1186/s13287-019-1544-y. Stem Cell Res Ther. 2020. PMID: 31918758 Free PMC article.

Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy.

Liang D, Han D, Fan W, Zhang R, Qiao H, Fan M, Su T, Ma S, Li X, Chen J, Wang Y, Ren J, Cao F. Liang D, et al. Sci Rep. 2016 Feb 23;6:21914. doi: 10.1038/srep21914. Sci Rep. 2016. PMID: 26902855 Free PMC article.

Autophagy alleviates the decrease in proliferation of amyloid β1‑42‑treated bone marrow mesenchymal stem cells via the AKT/mTOR signaling pathway.

Yang B, Cai Z, Zhang W, Yin D, Zhao W, Yang M. Yang B, et al. Mol Med Rep. 2019 May;19(5):4091-4100. doi: 10.3892/mmr.2019.10069. Epub 2019 Mar 21. Mol Med Rep. 2019. PMID: 30896831 Free PMC article.

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