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Items: 1 to 20 of 100

1.

Optical tools for understanding the complexity of β-cell signalling and insulin release.

Frank JA, Broichhagen J, Yushchenko DA, Trauner D, Schultz C, Hodson DJ.

Nat Rev Endocrinol. 2018 Dec;14(12):721-737. doi: 10.1038/s41574-018-0105-2. Review.

PMID:
30356209
2.

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.

Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N.

Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23.

PMID:
27338624
3.

Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?

Cantley J, Ashcroft FM.

BMC Biol. 2015 May 16;13:33. doi: 10.1186/s12915-015-0140-6. No abstract available. Erratum in: BMC Biol. 2019 Apr 9;17(1):32.

4.

Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.

Seino S.

Diabetologia. 2012 Aug;55(8):2096-108. doi: 10.1007/s00125-012-2562-9. Epub 2012 May 4. Review.

PMID:
22555472
5.

Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents.

Gerdes JM, Christou-Savina S, Xiong Y, Moede T, Moruzzi N, Karlsson-Edlund P, Leibiger B, Leibiger IB, Östenson CG, Beales PL, Berggren PO.

Nat Commun. 2014 Nov 6;5:5308. doi: 10.1038/ncomms6308.

PMID:
25374274
6.

Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats.

Rose T, Efendic S, Rupnik M.

J Gen Physiol. 2007 Jun;129(6):493-508.

7.

The required beta cell research for improving treatment of type 2 diabetes.

Thorens B.

J Intern Med. 2013 Sep;274(3):203-14. doi: 10.1111/joim.12096. Epub 2013 Jun 21. Review.

8.

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.

Rosengren AH, Braun M, Mahdi T, Andersson SA, Travers ME, Shigeto M, Zhang E, Almgren P, Ladenvall C, Axelsson AS, Edlund A, Pedersen MG, Jonsson A, Ramracheya R, Tang Y, Walker JN, Barrett A, Johnson PR, Lyssenko V, McCarthy MI, Groop L, Salehi A, Gloyn AL, Renström E, Rorsman P, Eliasson L.

Diabetes. 2012 Jul;61(7):1726-33. doi: 10.2337/db11-1516. Epub 2012 Apr 9.

9.

Asna1/TRC40 Controls β-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport.

Norlin S, Parekh VS, Naredi P, Edlund H.

Diabetes. 2016 Jan;65(1):110-9. doi: 10.2337/db15-0699. Epub 2015 Oct 5.

10.

MicroRNAs in islet hormone secretion.

Esguerra JLS, Nagao M, Ofori JK, Wendt A, Eliasson L.

Diabetes Obes Metab. 2018 Sep;20 Suppl 2:11-19. doi: 10.1111/dom.13382. Review.

PMID:
30230181
11.

Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes.

Granhall C, Rosengren AH, Renström E, Luthman H.

Diabetes. 2006 Dec;55(12):3494-500.

12.

Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells.

Rajasekaran SS, Kim J, Gaboardi GC, Gromada J, Shears SB, Dos Santos KT, Nolasco EL, Ferreira SS, Illies C, Köhler M, Gu C, Ryu SH, Martins JO, Darè E, Barker CJ, Berggren PO.

Cell Signal. 2018 Jun;46:120-128. doi: 10.1016/j.cellsig.2018.03.001. Epub 2018 Mar 6. Erratum in: Cell Signal. 2019 Jan;53:415.

13.

[Comeback for the beta cells in the pathogenesis of diabetes].

Mulder H.

Lakartidningen. 2010 Nov 10-16;107(45):2796-800. Review. Swedish. No abstract available.

PMID:
21179864
14.

The adenosine, adrenergic and opioid pathways in the regulation of insulin secretion, beta cell proliferation and regeneration.

Singh A, Gibert Y, Dwyer KM.

Pancreatology. 2018 Sep;18(6):615-623. doi: 10.1016/j.pan.2018.06.006. Epub 2018 Jun 20. Review.

PMID:
29937364
15.

The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice.

Bermudez-Silva FJ, Romero-Zerbo SY, Haissaguerre M, Ruz-Maldonado I, Lhamyani S, El Bekay R, Tabarin A, Marsicano G, Cota D.

Dis Model Mech. 2016 Jan;9(1):51-61. doi: 10.1242/dmm.020750. Epub 2015 Nov 12.

16.

Lipid signalling dynamics at the β-cell plasma membrane.

Wuttke A.

Basic Clin Pharmacol Toxicol. 2015 Apr;116(4):281-90. doi: 10.1111/bcpt.12369. Epub 2015 Jan 21. Review.

17.

Lysosomes in nutrient signalling: A focus on pancreatic β-cells.

Mészáros G, Pasquier A, Vivot K, Goginashvili A, Ricci R.

Diabetes Obes Metab. 2018 Sep;20 Suppl 2:104-115. doi: 10.1111/dom.13389.

PMID:
30230186
18.

Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics).

Kang T, Jensen P, Huang H, Lund Christensen G, Billestrup N, Larsen MR.

Mol Cell Proteomics. 2018 Jan;17(1):95-110. doi: 10.1074/mcp.RA117.000217. Epub 2017 Nov 7.

19.

Glucocorticoids and beta-cell function.

Fichna M, Fichna P.

Endokrynol Pol. 2017;68(5):568-573. doi: 10.5603/EP.2017.0060. Review.

20.

Impairment of pancreatic β-cell function by chronic intermittent hypoxia.

Wang N, Khan SA, Prabhakar NR, Nanduri J.

Exp Physiol. 2013 Sep;98(9):1376-85. doi: 10.1113/expphysiol.2013.072454. Epub 2013 May 24.

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