Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 101

1.

Progressive waves of IL-1β release by primary human monocytes via sequential activation of vesicular and gasdermin D-mediated secretory pathways.

Semino C, Carta S, Gattorno M, Sitia R, Rubartelli A.

Cell Death Dis. 2018 Oct 23;9(11):1088. doi: 10.1038/s41419-018-1121-9.

2.

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.

He WT, Wan H, Hu L, Chen P, Wang X, Huang Z, Yang ZH, Zhong CQ, Han J.

Cell Res. 2015 Dec;25(12):1285-98. doi: 10.1038/cr.2015.139. Epub 2015 Nov 27.

3.

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.

Monteleone M, Stanley AC, Chen KW, Brown DL, Bezbradica JS, von Pein JB, Holley CL, Boucher D, Shakespear MR, Kapetanovic R, Rolfes V, Sweet MJ, Stow JL, Schroder K.

Cell Rep. 2018 Aug 7;24(6):1425-1433. doi: 10.1016/j.celrep.2018.07.027.

4.

Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance.

Carta S, Penco F, Lavieri R, Martini A, Dinarello CA, Gattorno M, Rubartelli A.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2835-40. doi: 10.1073/pnas.1424741112. Epub 2015 Feb 17.

5.

Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1beta secretion.

Tassi S, Carta S, Delfino L, Caorsi R, Martini A, Gattorno M, Rubartelli A.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9789-94. doi: 10.1073/pnas.1000779107. Epub 2010 May 5.

6.

Toxoplasma gondii activates a Syk-CARD9-NF-κB signaling axis and gasdermin D-independent release of IL-1β during infection of primary human monocytes.

Pandori WJ, Lima TS, Mallya S, Kao TH, Gov L, Lodoen MB.

PLoS Pathog. 2019 Aug 26;15(8):e1007923. doi: 10.1371/journal.ppat.1007923. eCollection 2019 Aug.

7.

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.

Yang J, Liu Z, Wang C, Yang R, Rathkey JK, Pinkard OW, Shi W, Chen Y, Dubyak GR, Abbott DW, Xiao TS.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6792-6797. doi: 10.1073/pnas.1800562115. Epub 2018 Jun 11.

8.

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.

Xiao J, Wang C, Yao JC, Alippe Y, Xu C, Kress D, Civitelli R, Abu-Amer Y, Kanneganti TD, Link DC, Mbalaviele G.

PLoS Biol. 2018 Nov 2;16(11):e3000047. doi: 10.1371/journal.pbio.3000047. eCollection 2018 Nov.

9.

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release.

Rashidi M, Simpson DS, Hempel A, Frank D, Petrie E, Vince A, Feltham R, Murphy J, Chatfield SM, Salvesen GS, Murphy JM, Wicks IP, Vince JE.

J Immunol. 2019 Aug 1;203(3):736-748. doi: 10.4049/jimmunol.1900228. Epub 2019 Jun 17.

PMID:
31209100
10.

Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice.

Xu B, Jiang M, Chu Y, Wang W, Chen D, Li X, Zhang Z, Zhang D, Fan D, Nie Y, Shao F, Wu K, Liang J.

J Hepatol. 2018 Apr;68(4):773-782. doi: 10.1016/j.jhep.2017.11.040. Epub 2017 Dec 20.

PMID:
29273476
11.

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype.

Omenetti A, Carta S, Delfino L, Martini A, Gattorno M, Rubartelli A.

Ann Rheum Dis. 2014 Feb;73(2):462-9. doi: 10.1136/annrheumdis-2012-202774. Epub 2013 Mar 16.

PMID:
23505242
12.

Regulation of gasdermin D by miR-379-5p is involved in arsenite-induced activation of hepatic stellate cells and in fibrosis via secretion of IL-1β from human hepatic cells.

Li J, Xue J, Wang D, Dai X, Sun Q, Xiao T, Wu L, Xia H, Mostofa G, Chen X, Wei Y, Chen F, Quamruzzaman Q, Zhang A, Liu Q.

Metallomics. 2019 Feb 20;11(2):483-495. doi: 10.1039/c8mt00321a.

PMID:
30643918
13.

The unconventional secretion of IL-1β: Handling a dangerous weapon to optimize inflammatory responses.

Sitia R, Rubartelli A.

Semin Cell Dev Biol. 2018 Nov;83:12-21. doi: 10.1016/j.semcdb.2018.03.011. Epub 2018 Apr 5. Review.

PMID:
29571971
14.

Entamoeba histolytica-induced IL-1β secretion is dependent on caspase-4 and gasdermin D.

Quach J, Moreau F, Sandall C, Chadee K.

Mucosal Immunol. 2019 Mar;12(2):323-339. doi: 10.1038/s41385-018-0101-9. Epub 2018 Oct 25.

PMID:
30361535
15.

Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D.

Lei X, Zhang Z, Xiao X, Qi J, He B, Wang J.

J Virol. 2017 Aug 24;91(18). pii: e01069-17. doi: 10.1128/JVI.01069-17. Print 2017 Sep 15.

16.

IRF2 transcriptionally induces GSDMD expression for pyroptosis.

Kayagaki N, Lee BL, Stowe IB, Kornfeld OS, O'Rourke K, Mirrashidi KM, Haley B, Watanabe C, Roose-Girma M, Modrusan Z, Kummerfeld S, Reja R, Zhang Y, Cho V, Andrews TD, Morris LX, Goodnow CC, Bertram EM, Dixit VM.

Sci Signal. 2019 May 21;12(582). pii: eaax4917. doi: 10.1126/scisignal.aax4917.

PMID:
31113851
17.

Differential role of pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes.

Parzych K, Zetterqvist AV, Wright WR, Kirkby NS, Mitchell JA, Paul-Clark MJ.

FASEB J. 2017 Jun;31(6):2439-2445. doi: 10.1096/fj.201600256. Epub 2017 Feb 28.

18.

Structural Insight of Gasdermin Family Driving Pyroptotic Cell Death.

Ruan J.

Adv Exp Med Biol. 2019;1172:189-205. doi: 10.1007/978-981-13-9367-9_9.

PMID:
31628657
19.

Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria.

Wang J, Deobald K, Re F.

J Immunol. 2019 Jun 15;202(12):3468-3473. doi: 10.4049/jimmunol.1900045. Epub 2019 Apr 29.

PMID:
31036765
20.

The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages.

Chávez-Sánchez L, Chávez-Rueda K, Legorreta-Haquet MV, Zenteno E, Ledesma-Soto Y, Montoya-Díaz E, Tesoro-Cruz E, Madrid-Miller A, Blanco-Favela F.

Lipids Health Dis. 2010 Oct 14;9:117. doi: 10.1186/1476-511X-9-117.

Supplemental Content

Support Center