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Items: 1 to 20 of 100

1.

Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.

Hünerwadel A, Fagagnini S, Rogler G, Lutz C, Jaeger SU, Mamie C, Weder B, Ruiz PA, Hausmann M.

Sci Rep. 2018 Oct 12;8(1):15182. doi: 10.1038/s41598-018-33452-5.

2.

Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis.

Hutter S, van Haaften WT, Hünerwadel A, Baebler K, Herfarth N, Raselli T, Mamie C, Misselwitz B, Rogler G, Weder B, Dijkstra G, Meier CF, de Vallière C, Weber A, Imenez Silva PH, Wagner CA, Frey-Wagner I, Ruiz PA, Hausmann M.

J Crohns Colitis. 2018 Nov 15;12(11):1348-1358. doi: 10.1093/ecco-jcc/jjy118.

3.

BCL2 Regulates Differentiation of Intestinal Fibroblasts.

Weder B, Mamie C, Rogler G, Clarke S, McRae B, Ruiz PA, Hausmann M.

Inflamm Bowel Dis. 2018 May 22. doi: 10.1093/ibd/izy147. [Epub ahead of print]

PMID:
29796658
4.

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor.

Holvoet T, Devriese S, Castermans K, Boland S, Leysen D, Vandewynckel YP, Devisscher L, Van den Bossche L, Van Welden S, Dullaers M, Vandenbroucke RE, De Rycke R, Geboes K, Bourin A, Defert O, Hindryckx P, De Vos M, Laukens D.

Gastroenterology. 2017 Oct;153(4):1054-1067. doi: 10.1053/j.gastro.2017.06.013. Epub 2017 Jun 19.

PMID:
28642198
5.

Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation.

Scheibe K, Kersten C, Schmied A, Vieth M, Primbs T, Carlé B, Knieling F, Claussen J, Klimowicz AC, Zheng J, Baum P, Meyer S, Schürmann S, Friedrich O, Waldner MJ, Rath T, Wirtz S, Kollias G, Ekici AB, Atreya R, Raymond EL, Mbow ML, Neurath MF, Neufert C.

Gastroenterology. 2019 Mar;156(4):1082-1097.e11. doi: 10.1053/j.gastro.2018.11.029. Epub 2018 Nov 16.

PMID:
30452921
6.

Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis.

Breynaert C, de Bruyn M, Arijs I, Cremer J, Martens E, Van Lommel L, Geboes K, De Hertogh G, Schuit F, Ferrante M, Vermeire S, Ceuppens J, Opdenakker G, Van Assche G.

J Crohns Colitis. 2016 Nov;10(11):1336-1350. Epub 2016 May 17.

PMID:
27194531
7.

The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis.

Raselli T, Wyss A, Gonzalez Alvarado MN, Weder B, Mamie C, Spalinger MR, Van Haaften WT, Dijkstra G, Sailer AW, Imenez Silva PH, Wagner CA, Tosevski V, Leibl S, Scharl M, Rogler G, Hausmann M, Misselwitz B.

J Crohns Colitis. 2019 Sep 19;13(9):1186-1200. doi: 10.1093/ecco-jcc/jjz039.

8.

Oral pirfenidone protects against fibrosis by inhibiting fibroblast proliferation and TGF-β signaling in a murine colitis model.

Li G, Ren J, Hu Q, Deng Y, Chen G, Guo K, Li R, Li Y, Wu L, Wang G, Gu G, Li J.

Biochem Pharmacol. 2016 Oct 1;117:57-67. doi: 10.1016/j.bcp.2016.08.002. Epub 2016 Aug 4.

PMID:
27498142
9.

Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium.

Yamaguchi H, Suzuki K, Nagata M, Kawase T, Sukumaran V, Thandavarayan RA, Kawauchi Y, Yokoyama J, Tomita M, Kawachi H, Watanabe K, Yoneyama H, Asakura H, Takagi R.

Med Mol Morphol. 2012 Jun;45(3):140-51. Epub 2012 Sep 22.

PMID:
23001296
10.

Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.

Xue X, Ramakrishnan S, Anderson E, Taylor M, Zimmermann EM, Spence JR, Huang S, Greenson JK, Shah YM.

Gastroenterology. 2013 Oct;145(4):831-41. doi: 10.1053/j.gastro.2013.07.010. Epub 2013 Jul 13.

11.

Investigating intestinal inflammation in DSS-induced model of IBD.

Kim JJ, Shajib MS, Manocha MM, Khan WI.

J Vis Exp. 2012 Feb 1;(60). pii: 3678. doi: 10.3791/3678.

12.

Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease.

Breynaert C, Dresselaers T, Perrier C, Arijs I, Cremer J, Van Lommel L, Van Steen K, Ferrante M, Schuit F, Vermeire S, Rutgeerts P, Himmelreich U, Ceuppens JL, Geboes K, Van Assche G.

PLoS One. 2013 Jul 23;8(7):e68876. doi: 10.1371/journal.pone.0068876. Print 2013.

13.

Ro60 Inhibits Colonic Inflammation and Fibrosis in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis.

Kim SY, Park MJ, Kwon JE, Choi SY, Seo HB, Jung KA, Choi JW, Baek JA, Lee HH, Lee BI, Park SH, Cho ML.

Immunol Lett. 2018 Sep;201:45-51. doi: 10.1016/j.imlet.2018.11.001. Epub 2018 Nov 3. Erratum in: Immunol Lett. 2019 Jan 9;:.

PMID:
30395870
14.

Simvastatin attenuates intestinal fibrosis independent of the anti-inflammatory effect by promoting fibroblast/myofibroblast apoptosis in the regeneration/healing process from TNBS-induced colitis.

Abe Y, Murano M, Murano N, Morita E, Inoue T, Kawakami K, Ishida K, Kuramoto T, Kakimoto K, Okada T, Narabayashi K, Umegaki E, Higuchi K.

Dig Dis Sci. 2012 Feb;57(2):335-44. doi: 10.1007/s10620-011-1879-4. Epub 2011 Sep 11.

PMID:
21909991
15.

Pro- and anti-inflammatory cytokine gene single-nucleotide polymorphisms in inflammatory bowel disease.

López-Hernández R, Valdés M, Campillo JA, Martínez-García P, Salama H, Bolarin JM, Martínez H, Moya-Quiles MR, Minguela A, Sánchez-Torres A, Botella C, Salgado G, Miras M, Carballo F, Muro M.

Int J Immunogenet. 2015 Feb;42(1):38-45. doi: 10.1111/iji.12160. Epub 2014 Oct 31.

PMID:
25359546
16.

Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.

Uronis JM, Mühlbauer M, Herfarth HH, Rubinas TC, Jones GS, Jobin C.

PLoS One. 2009 Jun 24;4(6):e6026. doi: 10.1371/journal.pone.0006026.

17.

Longitudinal analysis of inflammation and microbiota dynamics in a model of mild chronic dextran sulfate sodium-induced colitis in mice.

De Fazio L, Cavazza E, Spisni E, Strillacci A, Centanni M, Candela M, Praticò C, Campieri M, Ricci C, Valerii MC.

World J Gastroenterol. 2014 Feb 28;20(8):2051-61. doi: 10.3748/wjg.v20.i8.2051.

18.

MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1.

He C, Yu T, Shi Y, Ma C, Yang W, Fang L, Sun M, Wu W, Xiao F, Guo F, Chen M, Yang H, Qian J, Cong Y, Liu Z.

Gastroenterology. 2017 May;152(6):1434-1448.e15. doi: 10.1053/j.gastro.2017.01.049. Epub 2017 Feb 11.

PMID:
28193514
19.

Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS)-induced colitis mouse model.

Woo JK, Choi S, Kang JH, Kim DE, Hurh BS, Jeon JE, Kim SY, Oh SH.

BMC Complement Altern Med. 2016 Dec 3;16(1):498.

20.

Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease.

Stidham RW, Xu J, Johnson LA, Kim K, Moons DS, McKenna BJ, Rubin JM, Higgins PD.

Gastroenterology. 2011 Sep;141(3):819-826.e1. doi: 10.1053/j.gastro.2011.07.027. Epub 2011 Jul 23.

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