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Items: 1 to 20 of 93

1.

Assessing the Effects of Ripasudil, a Novel Rho Kinase Inhibitor, on Human Corneal Endothelial Cell Health.

Goldstein AS, Aldrich BT, Skeie JM, Schmidt GA, Reed CR, Zimmerman MB, Greiner MA.

J Ocul Pharmacol Ther. 2018 Oct 12. doi: 10.1089/jop.2018.0063. [Epub ahead of print]

PMID:
30312120
2.

Effect of the Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) on Corneal Endothelial Wound Healing.

Okumura N, Okazaki Y, Inoue R, Kakutani K, Nakano S, Kinoshita S, Koizumi N.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1284-92. doi: 10.1167/iovs.15-18586.

PMID:
26998714
3.

Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Transiently Alters the Morphology of Corneal Endothelial Cells.

Okumura N, Okazaki Y, Inoue R, Nakano S, Fullwood NJ, Kinoshita S, Koizumi N.

Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7560-7. doi: 10.1167/iovs.15-17887.

PMID:
26618648
4.
5.

Use of Topical Rho Kinase Inhibitors in the Treatment of Fuchs Dystrophy After Descemet Stripping Only.

Macsai MS, Shiloach M.

Cornea. 2019 Feb 1. doi: 10.1097/ICO.0000000000001883. [Epub ahead of print]

PMID:
30720541
6.

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.

Nakagawa H, Koizumi N, Okumura N, Suganami H, Kinoshita S.

PLoS One. 2015 Sep 14;10(9):e0136802. doi: 10.1371/journal.pone.0136802. eCollection 2015.

7.

Vascular Normalization by ROCK Inhibitor: Therapeutic Potential of Ripasudil (K-115) Eye Drop in Retinal Angiogenesis and Hypoxia.

Yamaguchi M, Nakao S, Arita R, Kaizu Y, Arima M, Zhou Y, Kita T, Yoshida S, Kimura K, Isobe T, Kaneko Y, Sonoda KH, Ishibashi T.

Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2264-76. doi: 10.1167/iovs.15-17411.

PMID:
27124322
8.

The effects of ripasudil (K-115), a Rho kinase inhibitor, on activation of human conjunctival fibroblasts.

Futakuchi A, Inoue T, Fujimoto T, Inoue-Mochita M, Kawai M, Tanihara H.

Exp Eye Res. 2016 Aug;149:107-115. doi: 10.1016/j.exer.2016.07.001. Epub 2016 Jul 6.

PMID:
27394186
9.

Descemet stripping automated endothelial keratoplasty using cultured corneal endothelial cells in a rabbit model.

Honda N, Mimura T, Usui T, Amano S.

Arch Ophthalmol. 2009 Oct;127(10):1321-6. doi: 10.1001/archophthalmol.2009.253.

PMID:
19822849
10.

Effect of intravitreal Rho kinase inhibitor ripasudil (K-115) on feline retinal microcirculation.

Nakabayashi S, Kawai M, Yoshioka T, Song YS, Tani T, Yoshida A, Nagaoka T.

Exp Eye Res. 2015 Oct;139:132-5. doi: 10.1016/j.exer.2015.07.008. Epub 2015 Jul 18.

PMID:
26197413
11.

[Transplantation of corneal endothelial cells].

Amano S.

Nippon Ganka Gakkai Zasshi. 2002 Dec;106(12):805-35; discussion 836. Review. Japanese.

PMID:
12610838
12.

Effects of ripasudil hydrochloride hydrate (K-115), a Rho-kinase inhibitor, on ocular blood flow and ciliary artery smooth muscle contraction in rabbits.

Ohta Y, Takaseki S, Yoshitomi T.

Jpn J Ophthalmol. 2017 Sep;61(5):423-432. doi: 10.1007/s10384-017-0524-y. Epub 2017 Jun 26.

PMID:
28653193
13.

Regulation of functional corneal endothelial cells isolated from sphere colonies by Rho-associated protein kinase inhibitor.

Bi YL, Zhou Q, DU F, Wu MF, Xu GT, Sui GQ.

Exp Ther Med. 2013 Feb;5(2):433-437. Epub 2012 Nov 19.

14.

Additive Intraocular Pressure-Lowering Effects of the Rho Kinase Inhibitor Ripasudil (K-115) Combined With Timolol or Latanoprost: A Report of 2 Randomized Clinical Trials.

Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Suganami H, Araie M; K-115 Clinical Study Group.

JAMA Ophthalmol. 2015 Jul;133(7):755-61. doi: 10.1001/jamaophthalmol.2015.0525.

PMID:
25880207
15.

Ocular hypotensive effects of a Rho-associated protein kinase inhibitor in rabbits.

Kamaruddin MI, Nakamura-Shibasaki M, Mizuno Y, Kiuchi Y.

Clin Ophthalmol. 2017 Mar 31;11:591-597. doi: 10.2147/OPTH.S131416. eCollection 2017.

16.

Enhanced survival in vitro of human corneal endothelial cells using mouse embryonic stem cell conditioned medium.

Lu X, Chen D, Liu Z, Li C, Liu Y, Zhou J, Wan P, Mou YG, Wang Z.

Mol Vis. 2010 Apr 8;16:611-22.

17.

Relationship among oxidative stress, DNA damage, and proliferative capacity in human corneal endothelium.

Joyce NC, Zhu CC, Harris DL.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2116-22. doi: 10.1167/iovs.08-3007. Epub 2008 Dec 30.

PMID:
19117931
18.

Regional assessment of energy-producing metabolic activity in the endothelium of donor corneas.

Greiner MA, Burckart KA, Wagoner MD, Schmidt GA, Reed CR, Liaboe CA, Flamme-Wiese MJ, Zimmerman MB, Mullins RF, Kardon RH, Goins KM, Aldrich BT.

Invest Ophthalmol Vis Sci. 2015 May;56(5):2803-10. doi: 10.1167/iovs.15-16442.

PMID:
26024071
19.

Axonal Protection by Ripasudil, a Rho Kinase Inhibitor, via Modulating Autophagy in TNF-Induced Optic Nerve Degeneration.

Kitaoka Y, Sase K, Tsukahara C, Kojima K, Shiono A, Kogo J, Tokuda N, Takagi H.

Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5056-5064. doi: 10.1167/iovs.17-22000.

PMID:
28980003
20.

Effects of ripasudil, a ROCK inhibitor, on retinal edema and nonperfusion area in a retinal vein occlusion murine model.

Hida Y, Nakamura S, Nishinaka A, Inoue Y, Shimazawa M, Hara H.

J Pharmacol Sci. 2018 Jun;137(2):129-136. doi: 10.1016/j.jphs.2018.06.010. Epub 2018 Jun 19.

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