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Items: 1 to 20 of 104

1.

P2X Antagonists Inhibit HIV-1 Productive Infection and Inflammatory Cytokines Interleukin-10 (IL-10) and IL-1β in a Human Tonsil Explant Model.

Soare AY, Durham ND, Gopal R, Tweel B, Hoffman KW, Brown JA, O'Brien M, Bhardwaj N, Lim JK, Chen BK, Swartz TH.

J Virol. 2018 Dec 10;93(1). pii: e01186-18. doi: 10.1128/JVI.01186-18. Print 2019 Jan 1.

2.

P2X-selective purinergic antagonists are strong inhibitors of HIV-1 fusion during both cell-to-cell and cell-free infection.

Swartz TH, Esposito AM, Durham ND, Hartmann BM, Chen BK.

J Virol. 2014 Oct;88(19):11504-15. doi: 10.1128/JVI.01158-14. Epub 2014 Jul 16.

3.

Involvement of purinergic receptors and NOD-like receptor-family protein 3-inflammasome pathway in the adenosine triphosphate-induced cytokine release from macrophages.

Gicquel T, Victoni T, Fautrel A, Robert S, Gleonnec F, Guezingar M, Couillin I, Catros V, Boichot E, Lagente V.

Clin Exp Pharmacol Physiol. 2014 Apr;41(4):279-86. doi: 10.1111/1440-1681.12214.

PMID:
24472059
4.

P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release.

Barberà-Cremades M, Baroja-Mazo A, Gomez AI, Machado F, Di Virgilio F, Pelegrín P.

FASEB J. 2012 Jul;26(7):2951-62. doi: 10.1096/fj.12-205765. Epub 2012 Apr 6.

PMID:
22490780
5.

P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy.

Khalafalla MG, Woods LT, Camden JM, Khan AA, Limesand KH, Petris MJ, Erb L, Weisman GA.

J Biol Chem. 2017 Oct 6;292(40):16626-16637. doi: 10.1074/jbc.M117.790741. Epub 2017 Aug 10.

6.

ATP-induced IL-1β secretion is selectively impaired in microglia as compared to hematopoietic macrophages.

Burm SM, Zuiderwijk-Sick EA, Weert PM, Bajramovic JJ.

Glia. 2016 Dec;64(12):2231-2246. doi: 10.1002/glia.23059. Epub 2016 Sep 19.

PMID:
27641912
7.

Silica nanoparticles activate purinergic signaling via P2X7 receptor in dendritic cells, leading to production of pro-inflammatory cytokines.

Nakanishi K, Tsukimoto M, Tanuma S, Takeda K, Kojima S.

Toxicol In Vitro. 2016 Sep;35:202-11. doi: 10.1016/j.tiv.2016.06.003. Epub 2016 Jun 14.

PMID:
27311643
8.

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.

Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Gröne HJ, Schaefer L.

J Biol Chem. 2009 Sep 4;284(36):24035-48. doi: 10.1074/jbc.M109.014266. Epub 2009 Jul 15.

9.

P2X7 receptor inhibition attenuated sympathetic nerve sprouting after myocardial infarction via the NLRP3/IL-1β pathway.

Yin J, Wang Y, Hu H, Li X, Xue M, Cheng W, Wang Y, Li X, Yang N, Shi Y, Yan S.

J Cell Mol Med. 2017 Nov;21(11):2695-2710. doi: 10.1111/jcmm.13185. Epub 2017 May 4.

10.

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way.

Piccini A, Carta S, Tassi S, Lasiglié D, Fossati G, Rubartelli A.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8067-72. doi: 10.1073/pnas.0709684105. Epub 2008 Jun 3.

11.

Mechanical stress-induced interleukin-1beta expression through adenosine triphosphate/P2X7 receptor activation in human periodontal ligament cells.

Kanjanamekanant K, Luckprom P, Pavasant P.

J Periodontal Res. 2013 Apr;48(2):169-76. doi: 10.1111/j.1600-0765.2012.01517.x. Epub 2012 Aug 8.

PMID:
22881405
12.

Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection.

Lee BH, Hwang DM, Palaniyar N, Grinstein S, Philpott DJ, Hu J.

PLoS One. 2012;7(4):e35812. doi: 10.1371/journal.pone.0035812. Epub 2012 Apr 25.

13.

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage.

Pelegrin P, Barroso-Gutierrez C, Surprenant A.

J Immunol. 2008 Jun 1;180(11):7147-57.

14.

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages.

Gicquel T, Robert S, Loyer P, Victoni T, Bodin A, Ribault C, Gleonnec F, Couillin I, Boichot E, Lagente V.

FASEB J. 2015 Oct;29(10):4162-73. doi: 10.1096/fj.14-267393. Epub 2015 Jun 26.

PMID:
26116704
15.

HIV replication is associated to inflammasomes activation, IL-1β, IL-18 and caspase-1 expression in GALT and peripheral blood.

Feria MG, Taborda NA, Hernandez JC, Rugeles MT.

PLoS One. 2018 Apr 19;13(4):e0192845. doi: 10.1371/journal.pone.0192845. eCollection 2018.

16.

Peripheral P2X7 receptor-induced mechanical hyperalgesia is mediated by bradykinin.

Teixeira JM, de Oliveira-Fusaro MC, Parada CA, Tambeli CH.

Neuroscience. 2014 Sep 26;277:163-73. doi: 10.1016/j.neuroscience.2014.06.057. Epub 2014 Jul 2.

PMID:
24997266
17.

Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages.

Budai MM, Varga A, Milesz S, Tőzsér J, Benkő S.

Mol Immunol. 2013 Dec;56(4):471-9. doi: 10.1016/j.molimm.2013.05.005. Epub 2013 Aug 1.

PMID:
23911403
18.

Purinergic Receptors: Key Mediators of HIV-1 Infection and Inflammation.

Swartz TH, Dubyak GR, Chen BK.

Front Immunol. 2015 Nov 26;6:585. doi: 10.3389/fimmu.2015.00585. eCollection 2015. Review.

19.

[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors.

Donnelly-Roberts DL, Namovic MT, Surber B, Vaidyanathan SX, Perez-Medrano A, Wang Y, Carroll WA, Jarvis MF.

Neuropharmacology. 2009 Jan;56(1):223-9. doi: 10.1016/j.neuropharm.2008.06.012. Epub 2008 Jun 17.

PMID:
18602931
20.

Extracellular adenosine 5'-triphosphate and lipopolysaccharide induce interleukin-1β release in canine blood.

Spildrejorde M, Curtis SJ, Curtis BL, Sluyter R.

Vet Immunol Immunopathol. 2014 Jan 15;157(1-2):105-10. doi: 10.1016/j.vetimm.2013.11.002. Epub 2013 Nov 8.

PMID:
24290165

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