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Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer.

Schottelius M, Wurzer A, Wissmiller K, Beck R, Koch M, Gorpas D, Notni J, Buckle T, van Oosterom MN, Steiger K, Ntziachristos V, Schwaiger M, van Leeuwen FWB, Wester HJ. Schottelius M, et al. J Nucl Med. 2019 Jan;60(1):71-78. doi: 10.2967/jnumed.118.212720. Epub 2018 Sep 20. J Nucl Med. 2019. PMID: 30237214 Free PMC article.

Preclinical Evaluation and First Patient Application of 99mTc-PSMA-I&S for SPECT Imaging and Radioguided Surgery in Prostate Cancer.

Robu S, Schottelius M, Eiber M, Maurer T, Gschwend J, Schwaiger M, Wester HJ. Robu S, et al. J Nucl Med. 2017 Feb;58(2):235-242. doi: 10.2967/jnumed.116.178939. Epub 2016 Sep 15. J Nucl Med. 2017. PMID: 27635024 Free article.

68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies.

Weineisen M, Schottelius M, Simecek J, Baum RP, Yildiz A, Beykan S, Kulkarni HR, Lassmann M, Klette I, Eiber M, Schwaiger M, Wester HJ. Weineisen M, et al. J Nucl Med. 2015 Aug;56(8):1169-76. doi: 10.2967/jnumed.115.158550. Epub 2015 Jun 18. J Nucl Med. 2015. PMID: 26089548 Free article.

More advantages in detecting bone and soft tissue metastases from prostate cancer using ¹⁸F-PSMA PET/CT.

Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE. Pianou NK, et al. Hell J Nucl Med. 2019 Jan-Apr;22(1):6-9. doi: 10.1967/s002449910952. Epub 2019 Mar 7. Hell J Nucl Med. 2019. PMID: 30843003 Free article.

PSMA-11-Derived Dual-Labeled PSMA Inhibitors for Preoperative PET Imaging and Precise Fluorescence-Guided Surgery of Prostate Cancer.

Baranski AC, Schäfer M, Bauder-Wüst U, Roscher M, Schmidt J, Stenau E, Simpfendörfer T, Teber D, Maier-Hein L, Hadaschik B, Haberkorn U, Eder M, Kopka K. Baranski AC, et al. J Nucl Med. 2018 Apr;59(4):639-645. doi: 10.2967/jnumed.117.201293. Epub 2017 Nov 30. J Nucl Med. 2018. PMID: 29191856 Free article.

Synthesis and Evaluation of ⁶⁸Ga- and ¹⁷⁷Lu-Labeled (R)- vs (S)-DOTAGA Prostate-Specific Membrane Antigen-Targeting Derivatives.

Zhao R, Ploessl K, Zha Z, Choi S, Alexoff D, Zhu L, Kung HF. Zhao R, et al. Mol Pharm. 2020 Dec 7;17(12):4589-4602. doi: 10.1021/acs.molpharmaceut.0c00777. Epub 2020 Oct 27. Mol Pharm. 2020. PMID: 33108189

Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer.

Benešová M, Schäfer M, Bauder-Wüst U, Afshar-Oromieh A, Kratochwil C, Mier W, Haberkorn U, Kopka K, Eder M. Benešová M, et al. J Nucl Med. 2015 Jun;56(6):914-20. doi: 10.2967/jnumed.114.147413. Epub 2015 Apr 16. J Nucl Med. 2015. PMID: 25883127 Free article.

What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake.

Kuo HT, Lin KS, Zhang Z, Zhang C, Merkens H, Tan R, Roxin A, Uribe CF, Bénard F. Kuo HT, et al. Theranostics. 2022 Aug 21;12(14):6179-6188. doi: 10.7150/thno.76571. eCollection 2022. Theranostics. 2022. PMID: 36168623 Free PMC article.

Synthesis and evaluation of a novel urea-based ⁶⁸Ga-complex for imaging PSMA binding in tumor.

Zha Z, Ploessl K, Choi SR, Wu Z, Zhu L, Kung HF. Zha Z, et al. Nucl Med Biol. 2018 Apr;59:36-47. doi: 10.1016/j.nucmedbio.2017.12.007. Epub 2017 Dec 27. Nucl Med Biol. 2018. PMID: 29459281

In Vitro and In Vivo Characterization of an ¹⁸F-AlF-Labeled PSMA Ligand for Imaging of PSMA-Expressing Xenografts.

Lütje S, Franssen GM, Herrmann K, Boerman OC, Rijpkema M, Gotthardt M, Heskamp S. Lütje S, et al. J Nucl Med. 2019 Jul;60(7):1017-1022. doi: 10.2967/jnumed.118.218941. Epub 2019 Jan 17. J Nucl Med. 2019. PMID: 30655329 Free article.

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