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APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction.

Salamango DJ, Becker JT, McCann JL, Cheng AZ, Demir Ö, Amaro RE, Brown WL, Shaban NM, Harris RS.

Mol Cell Biol. 2018 Nov 13;38(23). pii: e00356-18. doi: 10.1128/MCB.00356-18. Print 2018 Dec 1.


Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity.

Li MM, Emerman M.

J Virol. 2011 Aug;85(16):8197-207. doi: 10.1128/JVI.00624-11. Epub 2011 Jun 8.


The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.

Shaban NM, Shi K, Lauer KV, Carpenter MA, Richards CM, Salamango D, Wang J, Lopresti MW, Banerjee S, Levin-Klein R, Brown WL, Aihara H, Harris RS.

Mol Cell. 2018 Jan 4;69(1):75-86.e9. doi: 10.1016/j.molcel.2017.12.010. Epub 2017 Dec 28.


Natural Polymorphisms and Oligomerization of Human APOBEC3H Contribute to Single-stranded DNA Scanning Ability.

Feng Y, Love RP, Ara A, Baig TT, Adolph MB, Chelico L.

J Biol Chem. 2015 Nov 6;290(45):27188-203. doi: 10.1074/jbc.M115.666065. Epub 2015 Sep 22.


APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces.

Salamango DJ, McCann JL, Demir Ö, Brown WL, Amaro RE, Harris RS.

J Mol Biol. 2018 Aug 17;430(17):2695-2708. doi: 10.1016/j.jmb.2018.04.044. Epub 2018 May 19.


Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A.

Love RP, Xu H, Chelico L.

J Biol Chem. 2012 Aug 31;287(36):30812-22. doi: 10.1074/jbc.M112.393181. Epub 2012 Jul 20.


The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H.

Binka M, Ooms M, Steward M, Simon V.

J Virol. 2012 Jan;86(1):49-59. doi: 10.1128/JVI.06082-11. Epub 2011 Oct 19.


Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities.

Mitra M, Singer D, Mano Y, Hritz J, Nam G, Gorelick RJ, Byeon IJ, Gronenborn AM, Iwatani Y, Levin JG.

Retrovirology. 2015 Jan 22;12:3. doi: 10.1186/s12977-014-0130-8.


Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H.

Harari A, Ooms M, Mulder LC, Simon V.

J Virol. 2009 Jan;83(1):295-303. doi: 10.1128/JVI.01665-08. Epub 2008 Oct 22.


Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.

Aynaud MM, Suspène R, Vidalain PO, Mussil B, Guétard D, Tangy F, Wain-Hobson S, Vartanian JP.

J Biol Chem. 2012 Nov 9;287(46):39182-92. doi: 10.1074/jbc.M112.372722. Epub 2012 Sep 13.


APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA.

Bohn JA, Thummar K, York A, Raymond A, Brown WC, Bieniasz PD, Hatziioannou T, Smith JL.

Nat Commun. 2017 Oct 18;8(1):1021. doi: 10.1038/s41467-017-01309-6.


Active nuclear import and cytoplasmic retention of activation-induced deaminase.

Patenaude AM, Orthwein A, Hu Y, Campo VA, Kavli B, Buschiazzo A, Di Noia JM.

Nat Struct Mol Biol. 2009 May;16(5):517-27. doi: 10.1038/nsmb.1598. Epub 2009 May 3.


APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic.

Bennett RP, Diner E, Sowden MP, Lees JA, Wedekind JE, Smith HC.

Biochem Biophys Res Commun. 2006 Nov 10;350(1):214-9. Epub 2006 Sep 18.


Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H.

Köck J, Blum HE.

J Gen Virol. 2008 May;89(Pt 5):1184-91. doi: 10.1099/vir.0.83507-0.


APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1.

Ooms M, Krikoni A, Kress AK, Simon V, Münk C.

J Virol. 2012 Jun;86(11):6097-108. doi: 10.1128/JVI.06570-11. Epub 2012 Mar 28.


Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity.

Refsland EW, Hultquist JF, Luengas EM, Ikeda T, Shaban NM, Law EK, Brown WL, Reilly C, Emerman M, Harris RS.

PLoS Genet. 2014 Nov 20;10(11):e1004761. doi: 10.1371/journal.pgen.1004761. eCollection 2014 Nov.


Simian Immunodeficiency Virus Vif and Human APOBEC3B Interactions Resemble Those between HIV-1 Vif and Human APOBEC3G.

Wang J, Shaban NM, Land AM, Brown WL, Harris RS.

J Virol. 2018 May 29;92(12). pii: e00447-18. doi: 10.1128/JVI.00447-18. Print 2018 Jun 15.


The mechanisms regulating the subcellular localization of AID.

Patenaude AM, Di Noia JM.

Nucleus. 2010 Jul-Aug;1(4):325-31. doi: 10.4161/nucl.1.4.12107. Epub 2010 Mar 31.


APOBEC3B lysine residues are dispensable for DNA cytosine deamination, HIV-1 restriction, and nuclear localization.

Molan AM, Hanson HM, Chweya CM, Anderson BD, Starrett GJ, Richards CM, Harris RS.

Virology. 2017 Nov;511:74-81. doi: 10.1016/j.virol.2017.08.025. Epub 2017 Aug 23.

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