Similar articles for PMID: 30195238

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1

ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism.

Granchi C. Granchi C. Eur J Med Chem. 2018 Sep 5;157:1276-1291. doi: 10.1016/j.ejmech.2018.09.001. Epub 2018 Sep 1. Eur J Med Chem. 2018. PMID: 30195238 Review.

2

ATP citrate lyase (ACLY): a promising target for cancer prevention and treatment.

Khwairakpam AD, Shyamananda MS, Sailo BL, Rathnakaram SR, Padmavathi G, Kotoky J, Kunnumakkara AB. Khwairakpam AD, et al. Curr Drug Targets. 2015;16(2):156-63. doi: 10.2174/1389450115666141224125117. Curr Drug Targets. 2015. PMID: 25537655 Review.

3

ATP citrate lyase inhibitors as novel cancer therapeutic agents.

Zu XY, Zhang QH, Liu JH, Cao RX, Zhong J, Yi GH, Quan ZH, Pizzorno G. Zu XY, et al. Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):154-67. doi: 10.2174/157489212799972954. Recent Pat Anticancer Drug Discov. 2012. PMID: 22339355 Review.

4

ATP citrate lyase: A central metabolic enzyme in cancer.

Icard P, Wu Z, Fournel L, Coquerel A, Lincet H, Alifano M. Icard P, et al. Cancer Lett. 2020 Feb 28;471:125-134. doi: 10.1016/j.canlet.2019.12.010. Epub 2019 Dec 9. Cancer Lett. 2020. PMID: 31830561 Review.

5

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.

Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE. Zhao S, et al. Cell Rep. 2016 Oct 18;17(4):1037-1052. doi: 10.1016/j.celrep.2016.09.069. Cell Rep. 2016. PMID: 27760311 Free PMC article.

6

An allosteric mechanism for potent inhibition of human ATP-citrate lyase.

Wei J, Leit S, Kuai J, Therrien E, Rafi S, Harwood HJ Jr, DeLaBarre B, Tong L. Wei J, et al. Nature. 2019 Apr;568(7753):566-570. doi: 10.1038/s41586-019-1094-6. Epub 2019 Apr 3. Nature. 2019. PMID: 30944472

7

Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells.

Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H. Migita T, et al. Int J Cancer. 2014 Jul 1;135(1):37-47. doi: 10.1002/ijc.28652. Epub 2013 Dec 18. Int J Cancer. 2014. PMID: 24310723 Free article.

8

ATP-citrate lyase: a key player in cancer metabolism.

Zaidi N, Swinnen JV, Smans K. Zaidi N, et al. Cancer Res. 2012 Aug 1;72(15):3709-14. doi: 10.1158/0008-5472.CAN-11-4112. Epub 2012 Jul 10. Cancer Res. 2012. PMID: 22787121 Review.

9

ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective.

Granchi C. Granchi C. Expert Opin Ther Pat. 2022 Jul;32(7):731-742. doi: 10.1080/13543776.2022.2067478. Epub 2022 Apr 25. Expert Opin Ther Pat. 2022. PMID: 35436171 Review.

10

ATP-citrate lyase multimerization is required for coenzyme-A substrate binding and catalysis.

Bazilevsky GA, Affronti HC, Wei X, Campbell SL, Wellen KE, Marmorstein R. Bazilevsky GA, et al. J Biol Chem. 2019 May 3;294(18):7259-7268. doi: 10.1074/jbc.RA118.006685. Epub 2019 Mar 15. J Biol Chem. 2019. PMID: 30877197 Free PMC article.

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