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Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis.

Salvamoser R, Brinkmann K, O'Reilly LA, Whitehead L, Strasser A, Herold MJ.

Cell Death Differ. 2019 Jun;26(6):1124-1137. doi: 10.1038/s41418-018-0188-2. Epub 2018 Aug 28.


Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions.

Deegan S, Saveljeva S, Logue SE, Pakos-Zebrucka K, Gupta S, Vandenabeele P, Bertrand MJ, Samali A.

Autophagy. 2014;10(11):1921-36. doi: 10.4161/15548627.2014.981790.


Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway.

Rao RV, Castro-Obregon S, Frankowski H, Schuler M, Stoka V, del Rio G, Bredesen DE, Ellerby HM.

J Biol Chem. 2002 Jun 14;277(24):21836-42. Epub 2002 Mar 27.


Caspases and their role in inflammation and ischemic neuronal death. Focus on caspase-12.

GarcĂ­a de la Cadena S, Massieu L.

Apoptosis. 2016 Jul;21(7):763-77. doi: 10.1007/s10495-016-1247-0. Review.


Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling.

Yamazaki T, Muramoto M, Oe T, Morikawa N, Okitsu O, Nagashima T, Nishimura S, Katayama Y, Kita Y.

Neuropharmacology. 2006 Apr;50(5):558-67. Epub 2006 Jan 4.


Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.

Mandal P, Feng Y, Lyons JD, Berger SB, Otani S, DeLaney A, Tharp GK, Maner-Smith K, Burd EM, Schaeffer M, Hoffman S, Capriotti C, Roback L, Young CB, Liang Z, Ortlund EA, DiPaolo NC, Bosinger S, Bertin J, Gough PJ, Brodsky IE, Coopersmith CM, Shayakhmetov DM, Mocarski ES.

Immunity. 2018 Jul 17;49(1):42-55.e6. doi: 10.1016/j.immuni.2018.06.011.


Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F, Shao F.

Nature. 2015 Oct 29;526(7575):660-5. doi: 10.1038/nature15514. Epub 2015 Sep 16.


Dual involvement of caspase-4 in inflammatory and ER stress-induced apoptotic responses in human retinal pigment epithelial cells.

Bian ZM, Elner SG, Elner VM.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):6006-14. doi: 10.1167/iovs.09-3628. Epub 2009 Jul 30.


Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling.

Anantharam V, Kanthasamy A, Choi CJ, Martin DP, Latchoumycandane C, Richt JA, Kanthasamy AG.

Free Radic Biol Med. 2008 Dec 1;45(11):1530-41. doi: 10.1016/j.freeradbiomed.2008.08.028. Epub 2008 Sep 13.


Benzene activates caspase-4 and -12 at the transcription level, without an association with apoptosis, in mouse bone marrow cells lacking the p53 gene.

Yi JY, Hirabayashi Y, Choi YK, Kodama Y, Kanno J, Han JH, Inoue T, Yoon BI.

Arch Toxicol. 2009 Aug;83(8):795-803. doi: 10.1007/s00204-009-0420-4. Epub 2009 Mar 27.


Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

Man SM, Karki R, Kanneganti TD.

Immunol Rev. 2017 May;277(1):61-75. doi: 10.1111/imr.12534. Review.


Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

Cheng KT, Xiong S, Ye Z, Hong Z, Di A, Tsang KM, Gao X, An S, Mittal M, Vogel SM, Miao EA, Rehman J, Malik AB.

J Clin Invest. 2017 Nov 1;127(11):4124-4135. doi: 10.1172/JCI94495. Epub 2017 Oct 9.


Anti-inflammatory activity of PYNOD and its mechanism in humans and mice.

Imamura R, Wang Y, Kinoshita T, Suzuki M, Noda T, Sagara J, Taniguchi S, Okamoto H, Suda T.

J Immunol. 2010 May 15;184(10):5874-84. doi: 10.4049/jimmunol.0900779. Epub 2010 Apr 14.


In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis.

Tu S, McStay GP, Boucher LM, Mak T, Beere HM, Green DR.

Nat Cell Biol. 2006 Jan;8(1):72-7. Epub 2005 Dec 18.


Old, new and emerging functions of caspases.

Shalini S, Dorstyn L, Dawar S, Kumar S.

Cell Death Differ. 2015 Apr;22(4):526-39. doi: 10.1038/cdd.2014.216. Epub 2014 Dec 19. Review.


Inflammatory caspases are innate immune receptors for intracellular LPS.

Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, Hu L, Shao F.

Nature. 2014 Oct 9;514(7521):187-92. doi: 10.1038/nature13683. Epub 2014 Aug 6.


Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors.

Wang Z, Cuddy M, Samuel T, Welsh K, Schimmer A, Hanaii F, Houghten R, Pinilla C, Reed JC.

J Biol Chem. 2004 Nov 12;279(46):48168-76. Epub 2004 Aug 27.


The Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome activation in macrophages.

Jakka P, Namani S, Murugan S, Rai N, Radhakrishnan G.

J Biol Chem. 2017 Dec 15;292(50):20613-20627. doi: 10.1074/jbc.M117.815878. Epub 2017 Oct 23.


The life span of short-lived plasma cells is partly determined by a block on activation of apoptotic caspases acting in combination with endoplasmic reticulum stress.

Auner HW, Beham-Schmid C, Dillon N, Sabbattini P.

Blood. 2010 Nov 4;116(18):3445-55. doi: 10.1182/blood-2009-10-250423. Epub 2010 Jul 22.

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