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Items: 1 to 20 of 89

1.

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency.

Hernandez N, Melki I, Jing H, Habib T, Huang SSY, Danielson J, Kula T, Drutman S, Belkaya S, Rattina V, Lorenzo-Diaz L, Boulai A, Rose Y, Kitabayashi N, Rodero MP, Dumaine C, Blanche S, Lebras MN, Leung MC, Mathew LS, Boisson B, Zhang SY, Boisson-Dupuis S, Giliani S, Chaussabel D, Notarangelo LD, Elledge SJ, Ciancanelli MJ, Abel L, Zhang Q, Marr N, Crow YJ, Su HC, Casanova JL.

J Exp Med. 2018 Oct 1;215(10):2567-2585. doi: 10.1084/jem.20180628. Epub 2018 Aug 24.

2.

Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9.

Li W, Hofer MJ, Songkhunawej P, Jung SR, Hancock D, Denyer G, Campbell IL.

J Biol Chem. 2017 Apr 7;292(14):5845-5859. doi: 10.1074/jbc.M116.756510. Epub 2017 Feb 17.

3.

STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1.

Blaszczyk K, Olejnik A, Nowicka H, Ozgyin L, Chen YL, Chmielewski S, Kostyrko K, Wesoly J, Balint BL, Lee CK, Bluyssen HA.

Biochem J. 2015 Mar 15;466(3):511-24. doi: 10.1042/BJ20140644.

4.

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections.

Wang W, Yin Y, Xu L, Su J, Huang F, Wang Y, Boor PPC, Chen K, Wang W, Cao W, Zhou X, Liu P, van der Laan LJW, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Sci Signal. 2017 Apr 25;10(476). pii: eaah4248. doi: 10.1126/scisignal.aah4248.

PMID:
28442624
5.

The unique role of STAT2 in constitutive and IFN-induced transcription and antiviral responses.

Blaszczyk K, Nowicka H, Kostyrko K, Antonczyk A, Wesoly J, Bluyssen HA.

Cytokine Growth Factor Rev. 2016 Jun;29:71-81. doi: 10.1016/j.cytogfr.2016.02.010. Epub 2016 Mar 18. Review.

6.

Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response.

Young DF, Didcock L, Goodbourn S, Randall RE.

Virology. 2000 Apr 10;269(2):383-90.

7.

Differential regulation of Tetraodon nigroviridis Mx gene promoter activity by constitutively-active forms of STAT1, STAT2, and IRF9.

Cheng CH, Chou CM, Chu CY, Chen GD, Lien HW, Hwang PP, Chang MS, Huang CJ.

Fish Shellfish Immunol. 2014 May;38(1):230-43. doi: 10.1016/j.fsi.2014.03.017. Epub 2014 Mar 27.

PMID:
24680831
8.

A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response.

Kraus TA, Lau JF, Parisien JP, Horvath CM.

J Biol Chem. 2003 Apr 11;278(15):13033-8. Epub 2003 Feb 5.

9.

Structural and functional characterization of salmon STAT1, STAT2 and IRF9 homologs sheds light on interferon signaling in teleosts.

Sobhkhez M, Skjesol A, Thomassen E, Tollersrud LG, Iliev DB, Sun B, Robertsen B, Jørgensen JB.

FEBS Open Bio. 2014 Oct 7;4:858-71. doi: 10.1016/j.fob.2014.09.007. eCollection 2014.

10.

Severe influenza pneumonitis in children with inherited TLR3 deficiency.

Lim HK, Huang SXL, Chen J, Kerner G, Gilliaux O, Bastard P, Dobbs K, Hernandez N, Goudin N, Hasek ML, García Reino EJ, Lafaille FG, Lorenzo L, Luthra P, Kochetkov T, Bigio B, Boucherit S, Rozenberg F, Vedrinne C, Keller MD, Itan Y, García-Sastre A, Celard M, Orange JS, Ciancanelli MJ, Meyts I, Zhang Q, Abel L, Notarangelo LD, Snoeck HW, Casanova JL, Zhang SY.

J Exp Med. 2019 Jun 19. pii: jem.20181621. doi: 10.1084/jem.20181621. [Epub ahead of print]

PMID:
31217193
11.

Mice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.

Hofer MJ, Li W, Manders P, Terry R, Lim SL, King NJ, Campbell IL.

J Virol. 2012 Jun;86(12):6932-46. doi: 10.1128/JVI.07147-11. Epub 2012 Apr 11.

12.

Interaction of IRF9 and STAT2 synergistically up-regulates IFN and PKR transcription in Ctenopharyngodon idella.

Wu Z, Wang L, Xu X, Lin G, Mao H, Ran X, Zhang T, Huang K, Wang H, Huang Q, Xu Q, Hu C.

Mol Immunol. 2017 May;85:273-282. doi: 10.1016/j.molimm.2017.03.013. Epub 2017 Mar 25.

PMID:
28347954
13.

The type I interferon-alpha mediates a more severe neurological disease in the absence of the canonical signaling molecule interferon regulatory factor 9.

Hofer MJ, Li W, Lim SL, Campbell IL.

J Neurosci. 2010 Jan 20;30(3):1149-57. doi: 10.1523/JNEUROSCI.3711-09.2010.

14.

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.

Poat B, Hazari S, Chandra PK, Gunduz F, Alvarez X, Balart LA, Garry RF, Dash S.

Virol J. 2010 Oct 12;7:265. doi: 10.1186/1743-422X-7-265.

15.

Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.

Zurney J, Kobayashi T, Holm GH, Dermody TS, Sherry B.

J Virol. 2009 Mar;83(5):2178-87. doi: 10.1128/JVI.01787-08. Epub 2008 Dec 24.

16.

Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.

Rauch I, Rosebrock F, Hainzl E, Heider S, Majoros A, Wienerroither S, Strobl B, Stockinger S, Kenner L, Müller M, Decker T.

Mol Cell Biol. 2015 Jul;35(13):2332-43. doi: 10.1128/MCB.01498-14. Epub 2015 Apr 27.

17.

Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.

Rengachari S, Groiss S, Devos JM, Caron E, Grandvaux N, Panne D.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E601-E609. doi: 10.1073/pnas.1718426115. Epub 2018 Jan 9.

18.

Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis.

Shi J, Zhang YB, Zhang JS, Gui JF.

Dev Comp Immunol. 2013 Dec;41(4):534-43. doi: 10.1016/j.dci.2013.07.017. Epub 2013 Aug 1.

PMID:
23916490
19.

A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription.

Platanitis E, Demiroz D, Schneller A, Fischer K, Capelle C, Hartl M, Gossenreiter T, Müller M, Novatchkova M, Decker T.

Nat Commun. 2019 Jul 2;10(1):2921. doi: 10.1038/s41467-019-10970-y.

20.

Porcine reproductive and respiratory syndrome virus inhibits type I interferon signaling by blocking STAT1/STAT2 nuclear translocation.

Patel D, Nan Y, Shen M, Ritthipichai K, Zhu X, Zhang YJ.

J Virol. 2010 Nov;84(21):11045-55. doi: 10.1128/JVI.00655-10. Epub 2010 Aug 25. Erratum in: J Virol. 2011 Jun;85(11):5705.

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