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Items: 1 to 20 of 95

1.

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology.

Kelemen LE, Earp M, Fridley BL, Chenevix-Trench G; Australian Ovarian Cancer Study Group, Fasching PA, Beckmann MW, Ekici AB, Hein A, Lambrechts D, Lambrechts S, Van Nieuwenhuysen E, Vergote I, Rossing MA, Doherty JA, Chang-Claude J, Behrens S, Moysich KB, Cannioto R, Lele S, Odunsi K, Goodman MT, Shvetsov YB, Thompson PJ, Wilkens LR, Dörk T, Antonenkova N, Bogdanova N, Hillemanns P, Runnebaum IB, du Bois A, Harter P, Heitz F, Schwaab I, Butzow R, Pelttari LM, Nevanlinna H, Modugno F, Edwards RP, Kelley JL, Ness RB, Karlan BY, Lester J, Orsulic S, Walsh C, Kjaer SK, Jensen A, Cunningham JM, Vierkant RA, Giles GG, Bruinsma F, Southey MC, Hildebrandt MAT, Liang D, Lu K, Wu X, Sellers TA, Levine DA, Schildkraut JM, Iversen ES, Terry KL, Cramer DW, Tworoger SS, Poole EM, Bandera EV, Olson SH, Orlow I, Vestrheim Thomsen LC, Bjorge L, Krakstad C, Tangen IL, Kiemeney LA, Aben KKH, Massuger LFAG, van Altena AM, Pejovic T, Bean Y, Kellar M, Cook LS, Le ND, Brooks-Wilson A, Gronwald J, Cybulski C, Jakubowska A, Lubiński J, Wentzensen N, Brinton LA, Lissowska J, Hogdall E, Engelholm SA, Hogdall C, Lundvall L, Nedergaard L, Pharoah PDP, Dicks E, Song H, Tyrer JP, McNeish I, Siddiqui N, Carty K, Glasspool R, Paul J, Campbell IG, Eccles D, Whittemore AS, McGuire V, Rothstein JH, Sieh W, Narod SA, Phelan CM, McLaughlin JR, Risch HA, Anton-Culver H, Ziogas A, Menon U, Gayther SA, Gentry-Maharaj A, Ramus SJ, Wu AH, Pearce CL, Lee AW, Pike MC, Kupryjanczyk J, Podgorska A, Plisiecka-Halasa J, Sawicki W, Goode EL, Berchuck A; Ovarian Cancer Association Consortium.

Int J Mol Sci. 2018 Aug 21;19(9). pii: E2473. doi: 10.3390/ijms19092473.

2.

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium.

Kelemen LE, Goodman MT, McGuire V, Rossing MA, Webb PM; Australian Cancer Study (Ovarian Cancer) Study Group, Köbel M, Anton-Culver H, Beesley J, Berchuck A, Brar S, Carney ME, Chang-Claude J, Chenevix-Trench G; Australian Ovarian Cancer Study Group, Cramer DW, Cunningham JM, Dicioccio RA, Doherty JA, Easton DF, Fredericksen ZS, Fridley BL, Gates MA, Gayther SA, Gentry-Maharaj A, Høgdall E, Kjaer SK, Lurie G, Menon U, Moorman PG, Moysich K, Ness RB, Palmieri RT, Pearce CL, Pharoah PD, Ramus SJ, Song H, Stram DO, Tworoger SS, Van Den Berg D, Vierkant RA, Wang-Gohrke S, Whittemore AS, Wilkens LR, Wu AH, Schildkraut JM, Sellers TA, Goode EL; Ovarian Cancer Association Consortium.

Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1822-30. doi: 10.1158/1055-9965.EPI-09-1317. Epub 2010 Jun 22.

3.

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS.

Rosmarin D, Palles C, Pagnamenta A, Kaur K, Pita G, Martin M, Domingo E, Jones A, Howarth K, Freeman-Mills L, Johnstone E, Wang H, Love S, Scudder C, Julier P, Fernández-Rozadilla C, Ruiz-Ponte C, Carracedo A, Castellvi-Bel S, Castells A, Gonzalez-Neira A, Taylor J, Kerr R, Kerr D, Tomlinson I.

Gut. 2015 Jan;64(1):111-20. doi: 10.1136/gutjnl-2013-306571. Epub 2014 Mar 19.

4.

Genome-wide significant risk associations for mucinous ovarian carcinoma.

Kelemen LE, Lawrenson K, Tyrer J, Li Q, Lee JM, Seo JH, Phelan CM, Beesley J, Chen X, Spindler TJ, Aben KK, Anton-Culver H, Antonenkova N; Australian Cancer Study; Australian Ovarian Cancer Study Group; Ovarian Cancer Association Consortium.

Nat Genet. 2015 Aug;47(8):888-97. doi: 10.1038/ng.3336. Epub 2015 Jun 15.

5.

Association of thymidylate synthase gene with endometrial cancer risk in a Chinese population.

Xu WH, Long JR, Zheng W, Ruan ZX, Cai Q, Cheng JR, Zhao GM, Xiang YB, Shu XO.

Cancer Epidemiol Biomarkers Prev. 2009 Feb;18(2):579-84. doi: 10.1158/1055-9965.EPI-08-0831. Epub 2009 Feb 3.

6.

Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium.

Ugai T, Kelemen LE, Mizuno M, Ong JS, Webb PM, Chenevix-Trench G; Australian Ovarian Cancer Study Group, Wicklund KG, Doherty JA, Rossing MA, Thompson PJ, Wilkens LR, Carney ME, Goodman MT, Schildkraut JM, Berchuck A, Cramer DW, Terry KL, Cai H, Shu XO, Gao YT, Xiang YB, Van Den Berg D, Pike MC, Wu AH, Pearce CL, Matsuo K; Ovarian Cancer Association Consortium.

Cancer Sci. 2018 Feb;109(2):435-445. doi: 10.1111/cas.13470. Epub 2018 Jan 21.

7.

The association between two polymorphisms in the TYMS gene and breast cancer risk: a meta-analysis.

Wang J, Wang B, Bi J, Di J.

Breast Cancer Res Treat. 2011 Jul;128(1):203-9. doi: 10.1007/s10549-010-1314-0. Epub 2010 Dec 25.

PMID:
21188629
8.

Polymorphisms of MUC16 (CA125) and MUC1 (CA15.3) in relation to ovarian cancer risk and survival.

Williams KA, Terry KL, Tworoger SS, Vitonis AF, Titus LJ, Cramer DW.

PLoS One. 2014 Feb 13;9(2):e88334. doi: 10.1371/journal.pone.0088334. eCollection 2014.

9.

Gene set-based analysis of mucinous ovarian carcinoma.

Chang CM, Wang PH, Horng HC.

Taiwan J Obstet Gynecol. 2017 Apr;56(2):210-216. doi: 10.1016/j.tjog.2016.12.016.

10.

p16(CDKN2) gene polymorphism: association with histologic subtypes of epithelial ovarian cancer in China.

Yan L, Na W, Shan K, Xiao-Wei M, Wei G, Shu-Cheng C.

Int J Gynecol Cancer. 2008 Jan-Feb;18(1):30-5. Epub 2007 Apr 26.

PMID:
17466040
11.

Tyms double (2R) and triple repeat (3R) confers risk for human oral squamous cell carcinoma.

Bezerra AM, Sant'Ana TA, Gomes AV, de Lacerda Vidal AK, Muniz MT.

Mol Biol Rep. 2014 Dec;41(12):7737-42. doi: 10.1007/s11033-014-3494-x. Epub 2014 Oct 24.

PMID:
25341694
12.

Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer.

Ntavatzikos A, Spathis A, Patapis P, Machairas N, Peros G, Konstantoudakis S, Leventakou D, Panayiotides IG, Karakitsos P, Koumarianou A.

World J Gastroenterol. 2017 Aug 28;23(32):5913-5924. doi: 10.3748/wjg.v23.i32.5913.

13.

Polymorphic thymidylate synthase gene impacts on overall survival of patients with epithelial ovarian cancer after platinum-based chemotherapy.

Biason P, Visentin M, Talamini R, Stopar A, Giorda G, Lucia E, Campagnutta E, Toffoli G.

Pharmacogenomics. 2012 Nov;13(14):1609-19. doi: 10.2217/pgs.12.136.

PMID:
23148637
14.

Is it necessary to perform routine appendectomy for mucinous ovarian neoplasms? A retrospective study and meta-analysis.

Cheng A, Li M, Kanis MJ, Xu Y, Zhang Q, Cui B, Jiang J, Zhang Y, Yang X, Kong B.

Gynecol Oncol. 2017 Jan;144(1):215-222. doi: 10.1016/j.ygyno.2016.10.041. Epub 2016 Nov 24. Review.

PMID:
27889016
15.

CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm.

Aktas D, Guney I, Alikasifoglu M, Yüce K, Tuncbilek E, Ayhan A.

Gynecol Oncol. 2002 Aug;86(2):124-8.

PMID:
12144816
16.

Regulation of multidrug resistance 1 expression by CDX2 in ovarian mucinous adenocarcinoma.

Koh I, Hinoi T, Sentani K, Hirata E, Nosaka S, Niitsu H, Miguchi M, Adachi T, Yasui W, Ohdan H, Kudo Y.

Cancer Med. 2016 Jul;5(7):1546-55. doi: 10.1002/cam4.697. Epub 2016 Apr 6.

17.

Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis shows multiple novel risk variants and leads for TYMS regulation.

Senapati S, Singh S, Das M, Kumar A, Gupta R, Kumar U, Jain S, Juyal RC, Thelma BK.

Pharmacogenet Genomics. 2014 Apr;24(4):211-9. doi: 10.1097/FPC.0000000000000036.

PMID:
24583629
18.

Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms.

Mackenzie R, Kommoss S, Winterhoff BJ, Kipp BR, Garcia JJ, Voss J, Halling K, Karnezis A, Senz J, Yang W, Prigge ES, Reuschenbach M, Doeberitz MV, Gilks BC, Huntsman DG, Bakkum-Gamez J, McAlpine JN, Anglesio MS.

BMC Cancer. 2015 May 19;15:415. doi: 10.1186/s12885-015-1421-8.

19.

EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients.

Rao ZY, Cai MY, Yang GF, He LR, Mai SJ, Hua WF, Liao YJ, Deng HX, Chen YC, Guan XY, Zeng YX, Kung HF, Xie D.

Carcinogenesis. 2010 Sep;31(9):1576-83. doi: 10.1093/carcin/bgq150. Epub 2010 Jul 28.

PMID:
20668008
20.

Thymidylate synthase pharmacogenetics.

Marsh S.

Invest New Drugs. 2005 Dec;23(6):533-7. Review.

PMID:
16267625

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