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Items: 1 to 20 of 107

1.

Galectins control MTOR and AMPK in response to lysosomal damage to induce autophagy.

Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V.

Autophagy. 2019 Jan;15(1):169-171. doi: 10.1080/15548627.2018.1505155. Epub 2018 Nov 5.

PMID:
30081722
2.

Galectins Control mTOR in Response to Endomembrane Damage.

Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V.

Mol Cell. 2018 Apr 5;70(1):120-135.e8. doi: 10.1016/j.molcel.2018.03.009.

3.

MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress.

Ozturk DG, Kocak M, Akcay A, Kinoglu K, Kara E, Buyuk Y, Kazan H, Gozuacik D.

Autophagy. 2019 Mar;15(3):375-390. doi: 10.1080/15548627.2018.1531197. Epub 2018 Oct 16.

PMID:
30290719
4.

The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.

Rui YN, Xu Z, Chen Z, Zhang S.

Autophagy. 2015;11(5):812-32. doi: 10.1080/15548627.2015.1034402.

5.

Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy.

Liu W, Jiang Y, Sun J, Geng S, Pan Z, Prinz RA, Wang C, Sun J, Jiao X, Xu X.

Cell Death Dis. 2018 May 1;9(5):570. doi: 10.1038/s41419-018-0612-z.

6.

Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression.

Giegerich AK, Kuchler L, Sha LK, Knape T, Heide H, Wittig I, Behrends C, Brüne B, von Knethen A.

Autophagy. 2014;10(11):1937-52. doi: 10.4161/auto.32178. Epub 2014 Oct 30.

7.

AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms.

Nwadike C, Williamson LE, Gallagher LE, Guan JL, Chan EYW.

Mol Cell Biol. 2018 Apr 30;38(10). pii: e00023-18. doi: 10.1128/MCB.00023-18. Print 2018 May 15.

8.

TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy.

Nnah IC, Wang B, Saqcena C, Weber GF, Bonder EM, Bagley D, De Cegli R, Napolitano G, Medina DL, Ballabio A, Dobrowolski R.

Autophagy. 2019 Jan;15(1):151-164. doi: 10.1080/15548627.2018.1511504. Epub 2018 Sep 10.

PMID:
30145926
9.

Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway.

Gui D, Cui Z, Zhang L, Yu C, Yao D, Xu M, Chen M, Wu P, Li G, Wang L, Huang X.

BMC Pulm Med. 2017 Dec 12;17(1):191. doi: 10.1186/s12890-017-0477-4.

10.

Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells.

Din FV, Valanciute A, Houde VP, Zibrova D, Green KA, Sakamoto K, Alessi DR, Dunlop MG.

Gastroenterology. 2012 Jun;142(7):1504-15.e3. doi: 10.1053/j.gastro.2012.02.050. Epub 2012 Mar 6.

11.

Digitoxin Suppresses Human Cytomegalovirus Replication via Na+, K+/ATPase α1 Subunit-Dependent AMP-Activated Protein Kinase and Autophagy Activation.

Mukhopadhyay R, Venkatadri R, Katsnelson J, Arav-Boger R.

J Virol. 2018 Feb 26;92(6). pii: e01861-17. doi: 10.1128/JVI.01861-17. Print 2018 Mar 15.

12.

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.

Bach M, Larance M, James DE, Ramm G.

Biochem J. 2011 Dec 1;440(2):283-91. doi: 10.1042/BJ20101894.

PMID:
21819378
13.

ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis.

Chung SJ, Nagaraju GP, Nagalingam A, Muniraj N, Kuppusamy P, Walker A, Woo J, Győrffy B, Gabrielson E, Saxena NK, Sharma D.

Autophagy. 2017 Aug 3;13(8):1386-1403. doi: 10.1080/15548627.2017.1332565. Epub 2017 Jul 11.

14.

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.

Shaw RJ.

Acta Physiol (Oxf). 2009 May;196(1):65-80. doi: 10.1111/j.1748-1716.2009.01972.x. Epub 2009 Feb 19. Review.

15.

5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complications.

Yao F, Zhang M, Chen L.

Acta Pharm Sin B. 2016 Jan;6(1):20-5. doi: 10.1016/j.apsb.2015.07.009. Epub 2015 Sep 3. Review.

16.

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK.

Shang L, Chen S, Du F, Li S, Zhao L, Wang X.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4788-93. doi: 10.1073/pnas.1100844108. Epub 2011 Mar 7.

17.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

18.

Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.

Jung J, Genau HM, Behrends C.

Mol Cell Biol. 2015 Jul;35(14):2479-94. doi: 10.1128/MCB.00125-15. Epub 2015 May 11.

19.

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.

Fernandez-Mosquera L, Yambire KF, Couto R, Pereyra L, Pabis K, Ponsford AH, Diogo CV, Stagi M, Milosevic I, Raimundo N.

Autophagy. 2019 Mar 27:1-20. doi: 10.1080/15548627.2019.1586256. [Epub ahead of print]

PMID:
30917721
20.

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.

Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garrè M, Morelli E, Vaccari T, Poletti A.

Autophagy. 2019 Apr;15(4):631-651. doi: 10.1080/15548627.2018.1535292. Epub 2018 Nov 5.

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