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Items: 1 to 20 of 106

1.

An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor.

Martinez-Martin N, Marcandalli J, Huang CS, Arthur CP, Perotti M, Foglierini M, Ho H, Dosey AM, Shriver S, Payandeh J, Leitner A, Lanzavecchia A, Perez L, Ciferri C.

Cell. 2018 Aug 23;174(5):1158-1171.e19. doi: 10.1016/j.cell.2018.06.028. Epub 2018 Jul 26.

2.

CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.

Vanarsdall AL, Pritchard SR, Wisner TW, Liu J, Jardetzky TS, Johnson DC.

MBio. 2018 May 8;9(3). pii: e00781-18. doi: 10.1128/mBio.00781-18.

3.
4.

The Human Cytomegalovirus Trimer and Pentamer Promote Sequential Steps in Entry into Epithelial and Endothelial Cells at Cell Surfaces and Endosomes.

Liu J, Jardetzky TS, Chin AL, Johnson DC, Vanarsdall AL.

J Virol. 2018 Oct 12;92(21). pii: e01336-18. doi: 10.1128/JVI.01336-18. Print 2018 Nov 1.

5.

Loss of the Human Cytomegalovirus US16 Protein Abrogates Virus Entry into Endothelial and Epithelial Cells by Reducing the Virion Content of the Pentamer.

Luganini A, Cavaletto N, Raimondo S, Geuna S, Gribaudo G.

J Virol. 2017 May 12;91(11). pii: e00205-17. doi: 10.1128/JVI.00205-17. Print 2017 Jun 1.

6.

Pathogen at the Gates: Human Cytomegalovirus Entry and Cell Tropism.

Nguyen CC, Kamil JP.

Viruses. 2018 Dec 11;10(12). pii: E704. doi: 10.3390/v10120704. Review.

7.

Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection.

Chiuppesi F, Wussow F, Johnson E, Bian C, Zhuo M, Rajakumar A, Barry PA, Britt WJ, Chakraborty R, Diamond DJ.

J Virol. 2015 Dec;89(23):11884-98. doi: 10.1128/JVI.01701-15. Epub 2015 Sep 16.

8.

Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes.

Ciferri C, Chandramouli S, Donnarumma D, Nikitin PA, Cianfrocco MA, Gerrein R, Feire AL, Barnett SW, Lilja AE, Rappuoli R, Norais N, Settembre EC, Carfi A.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1767-72. doi: 10.1073/pnas.1424818112. Epub 2015 Jan 26.

9.

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex.

Ha S, Li F, Troutman MC, Freed DC, Tang A, Loughney JW, Wang D, Wang IM, Vlasak J, Nickle DC, Rustandi RR, Hamm M, DePhillips PA, Zhang N, McLellan JS, Zhu H, Adler SP, McVoy MA, An Z, Fu TM.

J Virol. 2017 Mar 13;91(7). pii: e02033-16. doi: 10.1128/JVI.02033-16. Print 2017 Apr 1.

10.

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.

Soroceanu L, Akhavan A, Cobbs CS.

Nature. 2008 Sep 18;455(7211):391-5. doi: 10.1038/nature07209. Epub 2008 Aug 13.

PMID:
18701889
11.

Soluble Human Cytomegalovirus gH/gL/pUL128-131 Pentameric Complex, but Not gH/gL, Inhibits Viral Entry to Epithelial Cells and Presents Dominant Native Neutralizing Epitopes.

Loughney JW, Rustandi RR, Wang D, Troutman MC, Dick LW Jr, Li G, Liu Z, Li F, Freed DC, Price CE, Hoang VM, Culp TD, DePhillips PA, Fu TM, Ha S.

J Biol Chem. 2015 Jun 26;290(26):15985-95. doi: 10.1074/jbc.M115.652230. Epub 2015 May 6.

12.

Human Cytomegalovirus UL111A and US27 Gene Products Enhance the CXCL12/CXCR4 Signaling Axis via Distinct Mechanisms.

Tu CC, Arnolds KL, O'Connor CM, Spencer JV.

J Virol. 2018 Feb 12;92(5). pii: e01981-17. doi: 10.1128/JVI.01981-17. Print 2018 Mar 1.

13.

Entry of human cytomegalovirus into porcine endothelial cells depends on both the cellular vascular origin and the viral strain.

Taveira A, Ponroy N, Mueller NJ, Millard AL.

Xenotransplantation. 2014 Jul-Aug;21(4):324-40. doi: 10.1111/xen.12097. Epub 2014 Apr 8.

PMID:
24712388
14.

Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL.

Schultz EP, Lanchy JM, Ellerbeck EE, Ryckman BJ.

J Virol. 2015 Dec 9;90(5):2294-305. doi: 10.1128/JVI.01875-15.

15.

The Human Cytomegalovirus UL116 Gene Encodes an Envelope Glycoprotein Forming a Complex with gH Independently from gL.

Caló S, Cortese M, Ciferri C, Bruno L, Gerrein R, Benucci B, Monda G, Gentile M, Kessler T, Uematsu Y, Maione D, Lilja AE, Carfí A, Merola M.

J Virol. 2016 Apr 29;90(10):4926-38. doi: 10.1128/JVI.02517-15. Print 2016 May 15.

16.

HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission.

Vanarsdall AL, Chin AL, Liu J, Jardetzky TS, Mudd JO, Orloff SL, Streblow D, Mussi-Pinhata MM, Yamamoto AY, Duarte G, Britt WJ, Johnson DC.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3728-3733. doi: 10.1073/pnas.1814835116. Epub 2019 Feb 7.

17.

Production of Cytomegalovirus Dense Bodies by Scalable Bioprocess Methods Maintains Immunogenicity and Improves Neutralizing Antibody Titers.

Schneider-Ohrum K, Cayatte C, Liu Y, Wang Z, Irrinki A, Cataniag F, Nguyen N, Lambert S, Liu H, Aslam S, Duke G, McCarthy MP, McCormick L.

J Virol. 2016 Oct 28;90(22):10133-10144. doi: 10.1128/JVI.00463-16. Print 2016 Nov 15.

18.

From recognition to execution-the HCMV Pentamer from receptor binding to fusion triggering.

Malito E, Chandramouli S, Carfi A.

Curr Opin Virol. 2018 Aug;31:43-51. doi: 10.1016/j.coviro.2018.05.004. Epub 2018 Jun 1. Review.

PMID:
29866439
19.

Human Cytomegalovirus Tropism Modulator UL148 Interacts with SEL1L, a Cellular Factor That Governs Endoplasmic Reticulum-Associated Degradation of the Viral Envelope Glycoprotein gO.

Nguyen CC, Siddiquey MNA, Zhang H, Li G, Kamil JP.

J Virol. 2018 Aug 29;92(18). pii: e00688-18. doi: 10.1128/JVI.00688-18. Print 2018 Sep 15.

20.

OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism.

E X, Meraner P, Lu P, Perreira JM, Aker AM, McDougall WM, Zhuge R, Chan GC, Gerstein RM, Caposio P, Yurochko AD, Brass AL, Kowalik TF.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7043-7052. doi: 10.1073/pnas.1814850116. Epub 2019 Mar 20.

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