Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 100

1.

Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.

Miess E, Gondin AB, Yousuf A, Steinborn R, Mösslein N, Yang Y, Göldner M, Ruland JG, Bünemann M, Krasel C, Christie MJ, Halls ML, Schulz S, Canals M.

Sci Signal. 2018 Jul 17;11(539). pii: eaas9609. doi: 10.1126/scisignal.aas9609.

PMID:
30018083
2.

mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin.

Lowe JD, Celver JP, Gurevich VV, Chavkin C.

J Biol Chem. 2002 May 3;277(18):15729-35. Epub 2002 Feb 22.

3.

Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes.

Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C.

J Biol Chem. 2001 Feb 16;276(7):4894-900. Epub 2000 Nov 1.

4.

Homologous desensitization of signalling by the beta (beta) isoform of the human thromboxane A2 receptor.

Kelley-Hickie LP, Kinsella BT.

Biochim Biophys Acta. 2006 Sep;1761(9):1114-31. Epub 2006 Aug 3.

PMID:
16956790
5.
6.

Multiple functions of G protein-coupled receptor kinases.

Watari K, Nakaya M, Kurose H.

J Mol Signal. 2014 Mar 6;9(1):1. doi: 10.1186/1750-2187-9-1.

7.

Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.

Groer CE, Schmid CL, Jaeger AM, Bohn LM.

J Biol Chem. 2011 Sep 9;286(36):31731-41. doi: 10.1074/jbc.M111.248310. Epub 2011 Jul 14.

8.

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor.

Zheng H, Worrall C, Shen H, Issad T, Seregard S, Girnita A, Girnita L.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):7055-60. doi: 10.1073/pnas.1118359109. Epub 2012 Apr 16.

9.

Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.

Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH.

J Biol Chem. 2006 Mar 17;281(11):7684-92. Epub 2006 Jan 3.

10.

Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells.

Johnson EA, Oldfield S, Braksator E, Gonzalez-Cuello A, Couch D, Hall KJ, Mundell SJ, Bailey CP, Kelly E, Henderson G.

Mol Pharmacol. 2006 Aug;70(2):676-85. Epub 2006 May 8.

11.

Different mechanisms of homologous and heterologous μ-opioid receptor phosphorylation.

Mann A, Illing S, Miess E, Schulz S.

Br J Pharmacol. 2015 Jan;172(2):311-6. doi: 10.1111/bph.12627. Epub 2014 Jul 1. Review.

12.

Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G.

Br J Pharmacol. 2009 Sep;158(1):157-64. doi: 10.1111/j.1476-5381.2009.00140.x. Epub 2009 Mar 20.

13.

Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons.

Dang VC, Napier IA, Christie MJ.

J Neurosci. 2009 Mar 11;29(10):3322-7. doi: 10.1523/JNEUROSCI.4749-08.2009.

15.

Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation.

Qiu Y, Law PY, Loh HH.

J Biol Chem. 2003 Sep 19;278(38):36733-9. Epub 2003 Jul 14.

16.

G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor.

Namkung Y, Dipace C, Javitch JA, Sibley DR.

J Biol Chem. 2009 May 29;284(22):15038-51. doi: 10.1074/jbc.M900388200. Epub 2009 Mar 30.

17.
18.
19.

Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor.

Ren XR, Reiter E, Ahn S, Kim J, Chen W, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1448-53. Epub 2005 Jan 25.

Supplemental Content

Support Center