Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 102


Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.


FAT1 somatic mutations in head and neck carcinoma are associated with tumor progression and survival.

Lin SC, Lin LH, Yu SY, Kao SY, Chang KW, Cheng HW, Liu CJ.

Carcinogenesis. 2018 Dec 13;39(11):1320-1330. doi: 10.1093/carcin/bgy107.


Effects of the hippo signaling pathway in human gastric cancer.

Zhou GX, Li XY, Zhang Q, Zhao K, Zhang CP, Xue CH, Yang K, Tian ZB.

Asian Pac J Cancer Prev. 2013;14(9):5199-205.


The Characteristic of S100A7 Induction by the Hippo-YAP Pathway in Cervical and Glossopharyngeal Squamous Cell Carcinoma.

Kong F, Li Y, Hu E, Wang R, Wang J, Liu J, Zhang J, He D, Xiao X.

PLoS One. 2016 Dec 1;11(12):e0167080. doi: 10.1371/journal.pone.0167080. eCollection 2016.


Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion.

Vlahov N, Scrace S, Soto MS, Grawenda AM, Bradley L, Pankova D, Papaspyropoulos A, Yee KS, Buffa F, Goding CR, Timpson P, Sibson N, O'Neill E.

Curr Biol. 2015 Dec 7;25(23):3019-34. doi: 10.1016/j.cub.2015.09.072. Epub 2015 Nov 5.


Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover.

Hong X, Nguyen HT, Chen Q, Zhang R, Hagman Z, Voorhoeve PM, Cohen SM.

EMBO J. 2014 Nov 3;33(21):2447-57. doi: 10.15252/embj.201489385. Epub 2014 Sep 1.


Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.

Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8579-84. doi: 10.1073/pnas.0811691106. Epub 2009 May 13.


Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.

Liu J, Li J, Li P, Wang Y, Liang Z, Jiang Y, Li J, Feng C, Wang R, Chen H, Zhou C, Zhang J, Yang J, Liu P.

Sci Rep. 2017 Feb 7;7:42125. doi: 10.1038/srep42125.


Targeting YAP and Hippo signaling pathway in liver cancer.

Liu AM, Xu MZ, Chen J, Poon RT, Luk JM.

Expert Opin Ther Targets. 2010 Aug;14(8):855-68. doi: 10.1517/14728222.2010.499361. Review.


FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation.

Ahmed AF, de Bock CE, Lincz LF, Pundavela J, Zouikr I, Sontag E, Hondermarck H, Thorne RF.

Cell Mol Life Sci. 2015 Dec;72(23):4653-69. doi: 10.1007/s00018-015-1955-6. Epub 2015 Jun 24.


αE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway.

Li P, Silvis MR, Honaker Y, Lien WH, Arron ST, Vasioukhin V.

Genes Dev. 2016 Apr 1;30(7):798-811. doi: 10.1101/gad.274951.115. Epub 2016 Mar 24.


BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling.

Verma S, Yeddula N, Soda Y, Zhu Q, Pao G, Moresco J, Diedrich JK, Hong A, Plouffe S, Moroishi T, Guan KL, Verma IM.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7363-7370. doi: 10.1073/pnas.1822155116. Epub 2019 Mar 27.


miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis.

Kang W, Huang T, Zhou Y, Zhang J, Lung RWM, Tong JHM, Chan AWH, Zhang B, Wong CC, Wu F, Dong Y, Wang S, Yang W, Pan Y, Chak WP, Cheung AHK, Pang JCS, Yu J, Cheng ASL, To KF.

Cell Death Dis. 2018 Jan 24;9(2):92. doi: 10.1038/s41419-017-0134-0.


MST1/2 and YAP1 gene expression in acute myeloid leukemia.

Safari S, Movafagh A, Zare-Adollahi D, Ghadiani M, Riazi-Isfahani S, Safavi-Naini N, Omrani MD.

Leuk Lymphoma. 2014 Sep;55(9):2189-91. doi: 10.3109/10428194.2013.867493. Epub 2014 Feb 17. No abstract available.


The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma.

Alzahrani F, Clattenburg L, Muruganandan S, Bullock M, MacIsaac K, Wigerius M, Williams BA, Graham ME, Rigby MH, Trites JR, Taylor SM, Sinal CJ, Fawcett JP, Hart RD.

J Otolaryngol Head Neck Surg. 2017 Feb 22;46(1):15. doi: 10.1186/s40463-017-0187-1.


WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.

Zhang Y, Yan S, Chen J, Gan C, Chen D, Li Y, Wen J, Kremerskothen J, Chen S, Zhang J, Cao Y.

J Cell Mol Med. 2017 Dec;21(12):3718-3729. doi: 10.1111/jcmm.13281. Epub 2017 Aug 16.


Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, Takano Y, Hikasa H, Itoh T, Suzuki SO, Kurihara H, Aishima S, Leask A, Sasaki T, Nakano T, Nishina H, Nishikawa Y, Sekido Y, Nakao K, Shin-Ya K, Mimori K, Suzuki A.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E71-80. doi: 10.1073/pnas.1517188113. Epub 2015 Dec 22.


The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.

Chen M, Zhang H, Shi Z, Li Y, Zhang X, Gao Z, Zhou L, Ma J, Xu Q, Guan J, Cheng Y, Jiao S, Zhou Z.

J Biol Chem. 2018 Sep 14;293(37):14455-14469. doi: 10.1074/jbc.RA118.003279. Epub 2018 Aug 2.


Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.

Miyanaga A, Masuda M, Tsuta K, Kawasaki K, Nakamura Y, Sakuma T, Asamura H, Gemma A, Yamada T.

J Thorac Oncol. 2015 May;10(5):844-51. doi: 10.1097/JTO.0000000000000493.


The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.

Kodaka M, Hata Y.

Cell Mol Life Sci. 2015 Jan;72(2):285-306. doi: 10.1007/s00018-014-1742-9. Epub 2014 Sep 30. Review.


Supplemental Content

Support Center