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Molecular profiling of reticular gigantocellularis neurons indicates that eNOS modulates environmentally dependent levels of arousal.

Tabansky I, Liang Y, Frankfurt M, Daniels MA, Harrigan M, Stern S, Milner TA, Leshan R, Rama R, Moll T, Friedman JM, Stern JNH, Pfaff DW.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6900-E6909. doi: 10.1073/pnas.1806123115. Epub 2018 Jul 2.


Origins of arousal: roles for medullary reticular neurons.

Pfaff DW, Martin EM, Faber D.

Trends Neurosci. 2012 Aug;35(8):468-76. doi: 10.1016/j.tins.2012.04.008. Epub 2012 May 23.


Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects.

Stirone C, Boroujerdi A, Duckles SP, Krause DN.

Mol Pharmacol. 2005 Jan;67(1):105-13. Epub 2004 Oct 20.


Genetic elimination of eNOS reduces secondary complications of experimental subarachnoid hemorrhage.

Sabri M, Ai J, Lass E, D'abbondanza J, Macdonald RL.

J Cereb Blood Flow Metab. 2013 Jul;33(7):1008-14. doi: 10.1038/jcbfm.2013.49. Epub 2013 Apr 3.


Nitric oxide production during cerebral ischemia and reperfusion in eNOS- and nNOS-knockout mice.

Ito Y, Ohkubo T, Asano Y, Hattori K, Shimazu T, Yamazato M, Nagoya H, Kato Y, Araki N.

Curr Neurovasc Res. 2010 Feb;7(1):23-31.


Endothelial nitric oxide modulates expression and processing of amyloid precursor protein.

Austin SA, Santhanam AV, Katusic ZS.

Circ Res. 2010 Dec 10;107(12):1498-502. doi: 10.1161/CIRCRESAHA.110.233080. Epub 2010 Dec 2.


Targeted overexpression of endothelial nitric oxide synthase in endothelial cells improves cerebrovascular reactivity in Ins2Akita-type-1 diabetic mice.

Chandra SB, Mohan S, Ford BM, Huang L, Janardhanan P, Deo KS, Cong L, Muir ER, Duong TQ.

J Cereb Blood Flow Metab. 2016 Jun;36(6):1135-42. doi: 10.1177/0271678X15612098. Epub 2015 Oct 26.


Arousal-related reticular neurons during reduced oxygen tension: resilience and recovery of electrical activity.

Zhou J, Kow LM, Vannucci SJ, Pfaff D, Martin EM.

Dev Neurosci. 2009;31(4):255-8. doi: 10.1159/000216536. Epub 2009 Jun 17.


The Akt-endothelial nitric oxide synthase pathway in lipopolysaccharide preconditioning-induced hypoxic-ischemic tolerance in the neonatal rat brain.

Lin HY, Wu CL, Huang CC.

Stroke. 2010 Jul;41(7):1543-51. doi: 10.1161/STROKEAHA.109.574004. Epub 2010 May 27.


Development of Electrophysiological Properties of Nucleus Gigantocellularis Neurons Correlated with Increased CNS Arousal.

Liu X, Pfaff DW, Calderon DP, Tabansky I, Wang X, Wang Y, Kow LM.

Dev Neurosci. 2016;38(4):295-310. Epub 2016 Oct 28.


Neurovascular Protective Function of Endothelial Nitric Oxide - Recent Advances.

Katusic ZS, Austin SA.

Circ J. 2016 Jun 24;80(7):1499-503. doi: 10.1253/circj.CJ-16-0423. Epub 2016 May 25. Review.


Beta-amyloid accumulation in neurovascular units following brain embolism.

Han F, Fukunaga K.

J Pharmacol Sci. 2009 Oct;111(2):101-9. Epub 2009 Sep 26. Review.


Role of endothelial nitric oxide synthase in cerebral blood flow changes during kainate seizures: a genetic approach using knockout mice.

Pereira de Vasconcelos A, Riban V, Wasterlain C, Nehlig A.

Neurobiol Dis. 2006 Jul;23(1):219-27. Epub 2006 May 9.


Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.

Wood KC, Cortese-Krott MM, Kovacic JC, Noguchi A, Liu VB, Wang X, Raghavachari N, Boehm M, Kato GJ, Kelm M, Gladwin MT.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1861-71. doi: 10.1161/ATVBAHA.112.301068. Epub 2013 May 23.


Nitric oxide in B6 mouse and nitric oxide-sensitive soluble guanylate cyclase in cat modulate acetylcholine release in pontine reticular formation.

Lydic R, Garza-Grande R, Struthers R, Baghdoyan HA.

J Appl Physiol (1985). 2006 May;100(5):1666-73. Epub 2006 Jan 19.


Up-regulation of the RhoA/Rho-kinase signaling pathway in corpus cavernosum from endothelial nitric-oxide synthase (NOS), but not neuronal NOS, null mice.

Priviero FB, Jin LM, Ying Z, Teixeira CE, Webb RC.

J Pharmacol Exp Ther. 2010 Apr;333(1):184-92. doi: 10.1124/jpet.109.160606. Epub 2010 Jan 21. Erratum in: J Pharmacol Exp Ther. 2010 May;333(2):629.


Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling.

Lourenço CF, Ledo A, Barbosa RM, Laranjinha J.

Exp Neurol. 2017 May;291:36-43. doi: 10.1016/j.expneurol.2017.01.013. Epub 2017 Feb 1.


Endothelial nitric oxide synthase reduces crescentic and necrotic glomerular lesions, reactive oxygen production, and MCP1 production in murine lupus nephritis.

Gilkeson GS, Mashmoushi AK, Ruiz P, Caza TN, Perl A, Oates JC.

PLoS One. 2013 May 31;8(5):e64650. doi: 10.1371/journal.pone.0064650. Print 2013.


S-Nitrosation of β-catenin and p120 catenin: a novel regulatory mechanism in endothelial hyperpermeability.

Marín N, Zamorano P, Carrasco R, Mujica P, González FG, Quezada C, Meininger CJ, Boric MP, Durán WN, Sánchez FA.

Circ Res. 2012 Aug 17;111(5):553-63. doi: 10.1161/CIRCRESAHA.112.274548. Epub 2012 Jul 9.

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