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Items: 1 to 20 of 87

1.

Actin polymerization controls cilia-mediated signaling.

Drummond ML, Li M, Tarapore E, Nguyen TTL, Barouni BJ, Cruz S, Tan KC, Oro AE, Atwood SX.

J Cell Biol. 2018 Sep 3;217(9):3255-3266. doi: 10.1083/jcb.201703196. Epub 2018 Jun 26.

2.

GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.

Atwood SX, Li M, Lee A, Tang JY, Oro AE.

Nature. 2013 Feb 28;494(7438):484-8. doi: 10.1038/nature11889.

3.

The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.

Grzelak CA, Martelotto LG, Sigglekow ND, Patkunanathan B, Ajami K, Calabro SR, Dwyer BJ, Tirnitz-Parker JE, Watkins DN, Warner FJ, Shackel NA, McCaughan GW.

J Hepatol. 2014 Jan;60(1):143-51. doi: 10.1016/j.jhep.2013.08.012. Epub 2013 Aug 23.

PMID:
23978713
4.

Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.

Lee H, Ko HW.

Biochem Biophys Res Commun. 2016 Nov 25;480(4):574-579. doi: 10.1016/j.bbrc.2016.10.093. Epub 2016 Oct 26.

PMID:
27793670
5.

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.

Tukachinsky H, Lopez LV, Salic A.

J Cell Biol. 2010 Oct 18;191(2):415-28. doi: 10.1083/jcb.201004108.

6.

Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.

Yang N, Li L, Eguether T, Sundberg JP, Pazour GJ, Chen J.

Development. 2015 Jun 15;142(12):2194-202. doi: 10.1242/dev.115261. Epub 2015 May 28. Erratum in: Development. 2015 Aug 15;142(16):2860.

7.

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

Tuson M, He M, Anderson KV.

Development. 2011 Nov;138(22):4921-30. doi: 10.1242/dev.070805. Epub 2011 Oct 17.

8.

MIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling.

Bershteyn M, Atwood SX, Woo WM, Li M, Oro AE.

Dev Cell. 2010 Aug 17;19(2):270-83. doi: 10.1016/j.devcel.2010.07.009.

9.

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.

Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J.

PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug.

10.

Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.

Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT.

Genes Dev. 2014 Nov 15;28(22):2547-63. doi: 10.1101/gad.249425.114.

11.

Activation of the Gi protein-RHOA axis by non-canonical Hedgehog signaling is independent of primary cilia.

Ho Wei L, Arastoo M, Georgiou I, Manning DR, Riobo-Del Galdo NA.

PLoS One. 2018 Aug 27;13(8):e0203170. doi: 10.1371/journal.pone.0203170. eCollection 2018.

12.

The primary cilium at the crossroads of mammalian hedgehog signaling.

Wong SY, Reiter JF.

Curr Top Dev Biol. 2008;85:225-60. doi: 10.1016/S0070-2153(08)00809-0. Review.

13.

The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.

Spann AL, Yuan K, Goliwas KF, Steg AD, Kaushik DD, Kwon YJ, Frost AR.

Int J Oncol. 2015 Jul;47(1):269-79. doi: 10.3892/ijo.2015.3006. Epub 2015 May 15.

PMID:
25997440
14.

β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.

Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A, Cucchi D, Abballe L, Besharat ZM, Catanzaro G, Infante P, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I, Locatelli F, Ferretti E.

BMC Cancer. 2017 Jul 17;17(1):488. doi: 10.1186/s12885-017-3477-0.

15.

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.

He M, Subramanian R, Bangs F, Omelchenko T, Liem KF Jr, Kapoor TM, Anderson KV.

Nat Cell Biol. 2014 Jul;16(7):663-72. doi: 10.1038/ncb2988. Epub 2014 Jun 22.

16.

The primary cilium as a Hedgehog signal transduction machine.

Goetz SC, Ocbina PJ, Anderson KV.

Methods Cell Biol. 2009;94:199-222. doi: 10.1016/S0091-679X(08)94010-3. Epub 2009 Dec 23.

17.

Downregulation of ASPP2 promotes gallbladder cancer metastasis and macrophage recruitment via aPKC-ι/GLI1 pathway.

Tian L, Deng Z, Xu L, Yang T, Yao W, Ji L, Lu Y, Zhang J, Liu Y, Wang J.

Cell Death Dis. 2018 Nov 2;9(11):1115. doi: 10.1038/s41419-018-1145-1.

19.

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.

Mazumdar T, DeVecchio J, Agyeman A, Shi T, Houghton JA.

Oncotarget. 2011 Aug;2(8):638-45.

20.

Cilia and Hedgehog responsiveness in the mouse.

Huangfu D, Anderson KV.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30. Epub 2005 Aug 1.

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