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Items: 1 to 20 of 199

1.

Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD.

Shenouda M, Zhang AB, Weichert A, Robertson J.

Adv Neurobiol. 2018;20:239-263. doi: 10.1007/978-3-319-89689-2_9. Review.

PMID:
29916022
2.

The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.

Collins M, Riascos D, Kovalik T, An J, Krupa K, Krupa K, Hood BL, Conrads TP, Renton AE, Traynor BJ, Bowser R.

Acta Neuropathol. 2012 Nov;124(5):717-32. doi: 10.1007/s00401-012-1045-x. Epub 2012 Sep 21.

3.

The role of TDP-43 in the pathogenesis of ALS and FTLD.

Baralle M, Buratti E, Baralle FE.

Biochem Soc Trans. 2013 Dec;41(6):1536-40. doi: 10.1042/BST20130186. Review.

PMID:
24256250
4.

How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?

Baloh RH.

Curr Opin Neurol. 2012 Dec;25(6):701-7. doi: 10.1097/WCO.0b013e32835a269b. Review.

PMID:
23041957
5.

Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.

Tan RH, Yang Y, Kim WS, Dobson-Stone C, Kwok JB, Kiernan MC, Halliday GM.

Acta Neuropathol Commun. 2017 Oct 27;5(1):76. doi: 10.1186/s40478-017-0480-2.

6.

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies.

Geser F, Lee VM, Trojanowski JQ.

Neuropathology. 2010 Apr;30(2):103-12. doi: 10.1111/j.1440-1789.2009.01091.x. Epub 2010 Jan 25. Review.

7.

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Neumann M, Valori CF, Ansorge O, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ishihara K, Ang LC, Bilbao JM, Mackenzie IR.

Acta Neuropathol. 2012 Nov;124(5):705-16. doi: 10.1007/s00401-012-1020-6. Epub 2012 Jul 28.

PMID:
22842875
8.

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.

Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, Cuijt I, Smits V, Ceuterick-de Groote C, Van Broeckhoven C, Kumar-Singh S.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3858-63. doi: 10.1073/pnas.0912417107. Epub 2010 Feb 3.

9.

Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders.

Janssens J, Van Broeckhoven C.

Hum Mol Genet. 2013 Oct 15;22(R1):R77-87. doi: 10.1093/hmg/ddt349. Epub 2013 Jul 29. Review.

10.

Possible concurrence of TDP-43, tau and other proteins in amyotrophic lateral sclerosis/frontotemporal lobar degeneration.

Takeda T.

Neuropathology. 2018 Feb;38(1):72-81. doi: 10.1111/neup.12428. Epub 2017 Sep 27. Review.

PMID:
28960544
11.

RNA-binding proteins with prion-like domains in ALS and FTLD-U.

Gitler AD, Shorter J.

Prion. 2011 Jul-Sep;5(3):179-87. doi: 10.4161/pri.5.3.17230. Epub 2011 Jul 1. Review.

12.

Molecular basis of amyotrophic lateral sclerosis.

Liscic RM, Breljak D.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):370-2. doi: 10.1016/j.pnpbp.2010.07.017. Epub 2010 Jul 23. Review.

PMID:
20655970
13.

Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).

Bentmann E, Neumann M, Tahirovic S, Rodde R, Dormann D, Haass C.

J Biol Chem. 2012 Jun 29;287(27):23079-94. doi: 10.1074/jbc.M111.328757. Epub 2012 May 4.

14.

TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.

Maekawa S, Leigh PN, King A, Jones E, Steele JC, Bodi I, Shaw CE, Hortobagyi T, Al-Sarraj S.

Neuropathology. 2009 Dec;29(6):672-83. doi: 10.1111/j.1440-1789.2009.01029.x. Epub 2009 Jun 3.

PMID:
19496940
15.

Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.

Khosravi B, Hartmann H, May S, Möhl C, Ederle H, Michaelsen M, Schludi MH, Dormann D, Edbauer D.

Hum Mol Genet. 2017 Feb 15;26(4):790-800. doi: 10.1093/hmg/ddw432.

16.

Frontotemporal lobar degeneration and amyotrophic lateral sclerosis: molecular similarities and differences.

Neumann M.

Rev Neurol (Paris). 2013 Oct;169(10):793-8. doi: 10.1016/j.neurol.2013.07.019. Epub 2013 Sep 5. Review.

PMID:
24011641
17.

Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.

Ito D, Suzuki N.

Neurology. 2011 Oct 25;77(17):1636-43. doi: 10.1212/WNL.0b013e3182343365. Epub 2011 Sep 28. Review.

18.

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.

Moujalled D, Grubman A, Acevedo K, Yang S, Ke YD, Moujalled DM, Duncan C, Caragounis A, Perera ND, Turner BJ, Prudencio M, Petrucelli L, Blair I, Ittner LM, Crouch PJ, Liddell JR, White AR.

Hum Mol Genet. 2017 May 1;26(9):1732-1746. doi: 10.1093/hmg/ddx093.

PMID:
28334913
19.

TDP-43 and FUS: a nuclear affair.

Dormann D, Haass C.

Trends Neurosci. 2011 Jul;34(7):339-48. doi: 10.1016/j.tins.2011.05.002. Epub 2011 Jun 22.

PMID:
21700347
20.

Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma.

Bentmann E, Haass C, Dormann D.

FEBS J. 2013 Sep;280(18):4348-70. doi: 10.1111/febs.12287. Epub 2013 May 9. Review.

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