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Items: 1 to 20 of 98

1.

DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications.

Symmank J, Bayer C, Schmidt C, Hahn A, Pensold D, Zimmer-Bensch G.

Epigenetics. 2018;13(5):536-556. doi: 10.1080/15592294.2018.1475980. Epub 2018 Aug 7.

PMID:
29912614
2.

The DNA Methyltransferase 1 (DNMT1) Controls the Shape and Dynamics of Migrating POA-Derived Interneurons Fated for the Murine Cerebral Cortex.

Pensold D, Symmank J, Hahn A, Lingner T, Salinas-Riester G, Downie BR, Ludewig F, Rotzsch A, Haag N, Andreas N, Schubert K, Hübner CA, Pieler T, Zimmer G.

Cereb Cortex. 2017 Dec 1;27(12):5696-5714. doi: 10.1093/cercor/bhw341.

PMID:
29117290
3.

Single-Cell Transcriptomics Reveals Regulators of Neuronal Migration and Maturation During Brain Development.

Pensold D, Zimmer G.

J Exp Neurosci. 2018 Mar 8;12:1179069518760783. doi: 10.1177/1179069518760783. eCollection 2018.

4.

DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.

Ning X, Shi Z, Liu X, Zhang A, Han L, Jiang K, Kang C, Zhang Q.

Cancer Lett. 2015 Apr 10;359(2):198-205. doi: 10.1016/j.canlet.2015.01.005. Epub 2015 Jan 13.

PMID:
25595591
5.

Crosstalk Between Histone and DNA Methylation in Regulation of Retinal Matrix Metalloproteinase-9 in Diabetes.

Duraisamy AJ, Mishra M, Kowluru RA.

Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6440-6448. doi: 10.1167/iovs.17-22706.

6.

Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing.

Wu X, Gong Y, Yue J, Qiang B, Yuan J, Peng X.

Nucleic Acids Res. 2008 Jun;36(11):3590-9. doi: 10.1093/nar/gkn243. Epub 2008 May 6.

7.

Diverse facets of cortical interneuron migration regulation - Implications of neuronal activity and epigenetics.

Zimmer-Bensch G.

Brain Res. 2018 Dec 1;1700:160-169. doi: 10.1016/j.brainres.2018.09.001. Epub 2018 Sep 4. Review.

PMID:
30194015
8.

BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer.

Gong C, Yao S, Gomes AR, Man EP, Lee HJ, Gong G, Chang S, Kim SB, Fujino K, Kim SW, Park SK, Lee JW, Lee MH; KOHBRA study group, Khoo US, Lam EW.

Oncogenesis. 2016 Apr 4;5:e214. doi: 10.1038/oncsis.2016.23.

9.

The EZH2- H3K27me3-DNMT1 complex orchestrates epigenetic silencing of the wwc1 gene, a Hippo/YAP pathway upstream effector, in breast cancer epithelial cells.

Liu X, Li C, Zhang R, Xiao W, Niu X, Ye X, Li Z, Guo Y, Tan J, Li Y.

Cell Signal. 2018 Nov;51:243-256. doi: 10.1016/j.cellsig.2018.08.011. Epub 2018 Aug 16.

PMID:
30121333
10.

Regulation of neuronal survival by DNA methyltransferases.

Symmank J, Zimmer G.

Neural Regen Res. 2017 Nov;12(11):1768-1775. doi: 10.4103/1673-5374.219027. Review.

11.

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes.

Clements EG, Mohammad HP, Leadem BR, Easwaran H, Cai Y, Van Neste L, Baylin SB.

Nucleic Acids Res. 2012 May;40(10):4334-46. doi: 10.1093/nar/gks031. Epub 2012 Jan 25.

12.

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells.

Fiskus W, Buckley K, Rao R, Mandawat A, Yang Y, Joshi R, Wang Y, Balusu R, Chen J, Koul S, Joshi A, Upadhyay S, Atadja P, Bhalla KN.

Cancer Biol Ther. 2009 May;8(10):939-50. Epub 2009 May 18.

13.

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, Robertson KD.

Hum Mol Genet. 2008 Mar 1;17(5):690-709. Epub 2007 Nov 20.

PMID:
18029387
14.

Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer.

Hoffmann MJ, Engers R, Florl AR, Otte AP, Muller M, Schulz WA.

Cancer Biol Ther. 2007 Sep;6(9):1403-12.

PMID:
18637271
15.

Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis.

Lv YC, Tang YY, Zhang P, Wan W, Yao F, He PP, Xie W, Mo ZC, Shi JF, Wu JF, Peng J, Liu D, Cayabyab FS, Zheng XL, Tang XY, Ouyang XP, Tang CK.

PLoS One. 2016 Jun 13;11(6):e0157265. doi: 10.1371/journal.pone.0157265. eCollection 2016.

16.

EZH2 methyltransferase and H3K27 methylation in breast cancer.

Yoo KH, Hennighausen L.

Int J Biol Sci. 2012;8(1):59-65. Epub 2011 Nov 18. Review.

17.

Tumor Suppressive Function of p21-activated Kinase 6 in Hepatocellular Carcinoma.

Liu W, Liu Y, Liu H, Zhang W, Fu Q, Xu J, Gu J.

J Biol Chem. 2015 Nov 20;290(47):28489-501. doi: 10.1074/jbc.M115.658237. Epub 2015 Oct 6.

18.

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.

Sun F, Chan E, Wu Z, Yang X, Marquez VE, Yu Q.

Mol Cancer Ther. 2009 Dec;8(12):3191-202. doi: 10.1158/1535-7163.MCT-09-0479.

19.

Global histone H3 lysine 27 triple methylation levels are reduced in vessels with advanced atherosclerotic plaques.

Wierda RJ, Rietveld IM, van Eggermond MC, Belien JA, van Zwet EW, Lindeman JH, van den Elsen PJ.

Life Sci. 2015 May 15;129:3-9. doi: 10.1016/j.lfs.2014.10.010. Epub 2014 Oct 31.

PMID:
25445221
20.

Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells.

You JS, Kang JK, Lee EK, Lee JC, Lee SH, Jeon YJ, Koh DH, Ahn SH, Seo DW, Lee HY, Cho EJ, Han JW.

Oncogene. 2008 Feb 28;27(10):1376-86. Epub 2007 Sep 10.

PMID:
17828306

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