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Items: 1 to 20 of 97

1.

Cerebrospinal Fluid from Patients with Sporadic Amyotrophic Lateral Sclerosis Induces Degeneration of Motor Neurons Derived from Human Embryonic Stem Cells.

Sumitha R, Manjunatha VM, Sabitha RK, Alladi PA, Nalini A, Rao LT, Chandrasekhar Sagar BK, Steinbusch HWM, Kramer BW, Sathyaprabha TN, Raju TR.

Mol Neurobiol. 2018 Jun 1. doi: 10.1007/s12035-018-1149-y. [Epub ahead of print]

PMID:
29858777
2.

Vascular endothelial growth factor attenuates neurodegenerative changes in the NSC-34 motor neuron cell line induced by cerebrospinal fluid of sporadic amyotrophic lateral sclerosis patients.

Kulshreshtha D, Vijayalakshmi K, Alladi PA, Sathyaprabha TN, Nalini A, Raju TR.

Neurodegener Dis. 2011;8(5):322-30. doi: 10.1159/000323718. Epub 2011 Mar 10.

PMID:
21389676
3.

Evidence of endoplasmic reticular stress in the spinal motor neurons exposed to CSF from sporadic amyotrophic lateral sclerosis patients.

Vijayalakshmi K, Alladi PA, Ghosh S, Prasanna VK, Sagar BC, Nalini A, Sathyaprabha TN, Raju TR.

Neurobiol Dis. 2011 Mar;41(3):695-705. doi: 10.1016/j.nbd.2010.12.005. Epub 2010 Dec 16.

PMID:
21168498
4.

Exposure to cerebrospinal fluid of sporadic amyotrophic lateral sclerosis patients alters Nav1.6 and Kv1.6 channel expression in rat spinal motor neurons.

Gunasekaran R, Narayani RS, Vijayalakshmi K, Alladi PA, Shobha K, Nalini A, Sathyaprabha TN, Raju TR.

Brain Res. 2009 Feb 19;1255:170-9. doi: 10.1016/j.brainres.2008.11.099. Epub 2008 Dec 11.

PMID:
19109933
5.

Cerebrospinal Fluid from Sporadic Amyotrophic Lateral Sclerosis Patients Induces Mitochondrial and Lysosomal Dysfunction.

Sharma A, Varghese AM, Vijaylakshmi K, Sumitha R, Prasanna VK, Shruthi S, Chandrasekhar Sagar BK, Datta KK, Gowda H, Nalini A, Alladi PA, Christopher R, Sathyaprabha TN, Raju TR, Srinivas Bharath MM.

Neurochem Res. 2016 May;41(5):965-84. doi: 10.1007/s11064-015-1779-7. Epub 2015 Dec 8.

PMID:
26646005
6.

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Dafinca R, Scaber J, Ababneh N, Lalic T, Weir G, Christian H, Vowles J, Douglas AG, Fletcher-Jones A, Browne C, Nakanishi M, Turner MR, Wade-Martins R, Cowley SA, Talbot K.

Stem Cells. 2016 Aug;34(8):2063-78. doi: 10.1002/stem.2388. Epub 2016 May 4.

7.
8.

β-N-methylamino-l-alanine causes neurological and pathological phenotypes mimicking Amyotrophic Lateral Sclerosis (ALS): the first step towards an experimental model for sporadic ALS.

de Munck E, Muñoz-Sáez E, Miguel BG, Solas MT, Ojeda I, Martínez A, Gil C, Arahuetes RM.

Environ Toxicol Pharmacol. 2013 Sep;36(2):243-55. doi: 10.1016/j.etap.2013.04.007. Epub 2013 Apr 25.

PMID:
23688553
9.

Modeling amyotrophic lateral sclerosis in pure human iPSc-derived motor neurons isolated by a novel FACS double selection technique.

Toli D, Buttigieg D, Blanchard S, Lemonnier T, Lamotte d'Incamps B, Bellouze S, Baillat G, Bohl D, Haase G.

Neurobiol Dis. 2015 Oct;82:269-280. doi: 10.1016/j.nbd.2015.06.011. Epub 2015 Jun 21.

PMID:
26107889
10.

Cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients induces degeneration of a cultured motor neuron cell line.

Vijayalakshmi K, Alladi PA, Sathyaprabha TN, Subramaniam JR, Nalini A, Raju TR.

Brain Res. 2009 Mar 31;1263:122-33. doi: 10.1016/j.brainres.2009.01.041. Epub 2009 Feb 3.

PMID:
19368830
11.

Brain-Derived Neurotrophic Factor Facilitates Functional Recovery from ALS-Cerebral Spinal Fluid-Induced Neurodegenerative Changes in the NSC-34 Motor Neuron Cell Line.

Shruthi S, Sumitha R, Varghese AM, Ashok S, Chandrasekhar Sagar BK, Sathyaprabha TN, Nalini A, Kramer BW, Raju TR, Vijayalakshmi K, Alladi PA.

Neurodegener Dis. 2017;17(1):44-58. Epub 2016 Sep 13.

PMID:
27617773
12.

Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.

Jiang HQ, Ren M, Jiang HZ, Wang J, Zhang J, Yin X, Wang SY, Qi Y, Wang XD, Feng HL.

Neuroscience. 2014 Sep 26;277:132-8. doi: 10.1016/j.neuroscience.2014.03.047. Epub 2014 Mar 31.

PMID:
24699224
13.

Transient recovery in a rat model of familial amyotrophic lateral sclerosis after transplantation of motor neurons derived from mouse embryonic stem cells.

López-González R, Kunckles P, Velasco I.

Cell Transplant. 2009;18(10):1171-81. doi: 10.3727/096368909X12483162197123. Epub 2009 Aug 5.

PMID:
19660174
15.

Altered in-vitro and in-vivo expression of glial glutamate transporter-1 following exposure to cerebrospinal fluid of amyotrophic lateral sclerosis patients.

Shobha K, Vijayalakshmi K, Alladi PA, Nalini A, Sathyaprabha TN, Raju TR.

J Neurol Sci. 2007 Mar 15;254(1-2):9-16. Epub 2007 Jan 24.

PMID:
17254611
16.

Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.

Alves CJ, Dariolli R, Jorge FM, Monteiro MR, Maximino JR, Martins RS, Strauss BE, Krieger JE, Callegaro D, Chadi G.

Front Cell Neurosci. 2015 Aug 4;9:289. doi: 10.3389/fncel.2015.00289. eCollection 2015.

17.

Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons.

Lautenschläger J, Prell T, Ruhmer J, Weidemann L, Witte OW, Grosskreutz J.

Exp Neurol. 2013 Sep;247:91-100. doi: 10.1016/j.expneurol.2013.03.027. Epub 2013 Apr 8.

PMID:
23578819
18.

Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis.

Jiang YM, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizume Y, Sobue G.

J Neuropathol Exp Neurol. 2007 Jul;66(7):617-27.

PMID:
17620987
19.

Role of platelet derived growth factor (PDGF) in reverting neuronal nuclear and soma size alterations in NSC-34 cells exposed to cerebrospinal fluid from amyotrophic lateral sclerosis patients.

Chen YY, Liu XW, Gong TX, Zhang ZY, Liu YE, Zhang YB, Xiang LB, Xia H.

Clin Neurol Neurosurg. 2014 May;120:1-5. doi: 10.1016/j.clineuro.2014.02.004. Epub 2014 Feb 18.

PMID:
24731566
20.

Neuroprotective Effect of Human Adipose Stem Cell-Derived Extract in Amyotrophic Lateral Sclerosis.

Jeon GS, Im W, Shim YM, Lee M, Kim MJ, Hong YH, Seong SY, Kim M, Sung JJ.

Neurochem Res. 2016 Apr;41(4):913-23. doi: 10.1007/s11064-015-1774-z. Epub 2015 Dec 8.

PMID:
26646002

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