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Items: 1 to 20 of 95

1.

MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study.

Tourbah A, Gout O, Vighetto A, Deburghgraeve V, Pelletier J, Papeix C, Lebrun-Frenay C, Labauge P, Brassat D, Toosy A, Laplaud DA, Outteryck O, Moreau T, Debouverie M, Clavelou P, Heinzlef O, De Sèze J, Defer G, Sedel F, Arndt C.

CNS Drugs. 2018 Jul;32(7):661-672. doi: 10.1007/s40263-018-0528-2.

2.

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.

Tourbah A, Lebrun-Frenay C, Edan G, Clanet M, Papeix C, Vukusic S, De Sèze J, Debouverie M, Gout O, Clavelou P, Defer G, Laplaud DA, Moreau T, Labauge P, Brochet B, Sedel F, Pelletier J; MS-SPI study group.

Mult Scler. 2016 Nov;22(13):1719-1731. Epub 2016 Sep 1.

3.

Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial.

Raftopoulos R, Hickman SJ, Toosy A, Sharrack B, Mallik S, Paling D, Altmann DR, Yiannakas MC, Malladi P, Sheridan R, Sarrigiannis PG, Hoggard N, Koltzenburg M, Gandini Wheeler-Kingshott CA, Schmierer K, Giovannoni G, Miller DH, Kapoor R.

Lancet Neurol. 2016 Mar;15(3):259-69. doi: 10.1016/S1474-4422(16)00004-1. Epub 2016 Jan 26.

PMID:
26822749
4.

Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis.

Peyro Saint Paul L, Debruyne D, Bernard D, Mock DM, Defer GL.

Expert Opin Drug Metab Toxicol. 2016;12(3):327-44. doi: 10.1517/17425255.2016.1136288. Epub 2016 Feb 17. Review.

PMID:
26699811
5.

Retinal nerve fibre layer thinning is associated with worse visual outcome after optic neuritis in children with a relapsing demyelinating syndrome.

Eyre M, Hameed A, Wright S, Brownlee W, Ciccarelli O, Bowman R, Lim M, Wassmer E, Thompson D, Hemingway C, Hacohen Y.

Dev Med Child Neurol. 2018 Dec;60(12):1244-1250. doi: 10.1111/dmcn.13757. Epub 2018 Apr 11.

PMID:
29637998
6.

Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis.

Fisher JB, Jacobs DA, Markowitz CE, Galetta SL, Volpe NJ, Nano-Schiavi ML, Baier ML, Frohman EM, Winslow H, Frohman TC, Calabresi PA, Maguire MG, Cutter GR, Balcer LJ.

Ophthalmology. 2006 Feb;113(2):324-32. Epub 2006 Jan 10.

PMID:
16406539
7.

A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis.

Sühs KW, Hein K, Sättler MB, Görlitz A, Ciupka C, Scholz K, Käsmann-Kellner B, Papanagiotou P, Schäffler N, Restemeyer C, Bittersohl D, Hassenstein A, Seitz B, Reith W, Fassbender K, Hilgers R, Heesen C, Bähr M, Diem R.

Ann Neurol. 2012 Aug;72(2):199-210. doi: 10.1002/ana.23573.

PMID:
22926853
8.

[Retinal atrophy using optical coherence tomography (OCT) in 15 patients with multiple sclerosis and comparison with healthy subjects].

Jeanjean L, Castelnovo G, Carlander B, Villain M, Mura F, Dupeyron G, Labauge P.

Rev Neurol (Paris). 2008 Nov;164(11):927-34. doi: 10.1016/j.neurol.2008.03.008. Epub 2008 Jun 6. French.

PMID:
18808761
9.

Mitoxantrone: a review of its use in multiple sclerosis.

Scott LJ, Figgitt DP.

CNS Drugs. 2004;18(6):379-96. Review.

PMID:
15089110
10.

Monocular and binocular low-contrast visual acuity and optical coherence tomography in pediatric multiple sclerosis.

Waldman AT, Hiremath G, Avery RA, Conger A, Pineles SL, Loguidice MJ, Talman LS, Galetta KM, Shumski MJ, Wilson J, Ford E, Lavery AM, Conger D, Greenberg BM, Ellenberg JH, Frohman EM, Balcer LJ, Calabresi PA.

Mult Scler Relat Disord. 2013 May 1;3(3):326-334.

11.

Evaluation of retinal nerve fibre layer thickness and visual evoked potentials in optic neuritis associated with multiple sclerosis.

Chatziralli IP, Moschos MM, Brouzas D, Kopsidas K, Ladas ID.

Clin Exp Optom. 2012 Mar;95(2):223-8. doi: 10.1111/j.1444-0938.2012.00706.x. Epub 2012 Feb 13.

13.

Amiloride Clinical Trial In Optic Neuritis (ACTION) protocol: a randomised, double blind, placebo controlled trial.

McKee JB, Elston J, Evangelou N, Gerry S, Fugger L, Kennard C, Kong Y, Palace J, Craner M.

BMJ Open. 2015 Nov 9;5(11):e009200. doi: 10.1136/bmjopen-2015-009200.

14.

Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial.

Cadavid D, Balcer L, Galetta S, Aktas O, Ziemssen T, Vanopdenbosch L, Frederiksen J, Skeen M, Jaffe GJ, Butzkueven H, Ziemssen F, Massacesi L, Chai Y, Xu L, Freeman S; RENEW Study Investigators.

Lancet Neurol. 2017 Mar;16(3):189-199. doi: 10.1016/S1474-4422(16)30377-5. Epub 2017 Feb 15.

PMID:
28229892
15.

Ganglion cell loss in relation to visual disability in multiple sclerosis.

Walter SD, Ishikawa H, Galetta KM, Sakai RE, Feller DJ, Henderson SB, Wilson JA, Maguire MG, Galetta SL, Frohman E, Calabresi PA, Schuman JS, Balcer LJ.

Ophthalmology. 2012 Jun;119(6):1250-7. doi: 10.1016/j.ophtha.2011.11.032. Epub 2012 Feb 23.

16.

A double-blind, placebo-controlled trial of adding erythropoietin to intravenous methylprednisolone for the treatment of unilateral acute optic neuritis of unknown or demyelinative origin.

Shayegannejad V, Shahzamani S, Dehghani A, Dast Borhan Z, Rahimi M, Mirmohammadsadeghi A.

Graefes Arch Clin Exp Ophthalmol. 2015 May;253(5):797-801. doi: 10.1007/s00417-014-2925-7. Epub 2015 Jan 22.

PMID:
25605544
17.

Steroids for traumatic optic neuropathy.

Yu-Wai-Man P, Griffiths PG.

Cochrane Database Syst Rev. 2013 Jun 17;(6):CD006032. doi: 10.1002/14651858.CD006032.pub4. Review.

PMID:
23771729
18.

Steroids for traumatic optic neuropathy.

Yu-Wai-Man P, Griffiths PG.

Cochrane Database Syst Rev. 2011 Jan 19;(1):CD006032. doi: 10.1002/14651858.CD006032.pub3. Review. Update in: Cochrane Database Syst Rev. 2013;6:CD006032.

PMID:
21249673
19.

Oral lipoic acid as a treatment for acute optic neuritis: a blinded, placebo controlled randomized trial.

Falardeau J, Fryman A, Wanchu R, Marracci GH, Mass M, Wooliscroft L, Bourdette DN, Murchison CF, Hills WL, Yadav V.

Mult Scler J Exp Transl Clin. 2019 May 13;5(2):2055217319850193. doi: 10.1177/2055217319850193. eCollection 2019 Apr-Jun.

20.

Macular grid laser photocoagulation for branch retinal vein occlusion.

Lam FC, Chia SN, Lee RM.

Cochrane Database Syst Rev. 2015 May 11;(5):CD008732. doi: 10.1002/14651858.CD008732.pub2. Review.

PMID:
25961835

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