Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 102

1.

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.

Moghaddas F, Zeng P, Zhang Y, Schützle H, Brenner S, Hofmann SR, Berner R, Zhao Y, Lu B, Chen X, Zhang L, Cheng S, Winkler S, Lehmberg K, Canna SW, Czabotar PE, Wicks IP, De Nardo D, Hedrich CM, Zeng H, Masters SL.

J Allergy Clin Immunol. 2018 Dec;142(6):1956-1967.e6. doi: 10.1016/j.jaci.2018.04.033. Epub 2018 May 17.

2.

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.

Canna SW, de Jesus AA, Gouni S, Brooks SR, Marrero B, Liu Y, DiMattia MA, Zaal KJ, Sanchez GA, Kim H, Chapelle D, Plass N, Huang Y, Villarino AV, Biancotto A, Fleisher TA, Duncan JA, O'Shea JJ, Benseler S, Grom A, Deng Z, Laxer RM, Goldbach-Mansky R.

Nat Genet. 2014 Oct;46(10):1140-6. doi: 10.1038/ng.3089. Epub 2014 Sep 14.

3.

A Disease-associated Mutant of NLRC4 Shows Enhanced Interaction with SUG1 Leading to Constitutive FADD-dependent Caspase-8 Activation and Cell Death.

Raghawan AK, Sripada A, Gopinath G, Pushpanjali P, Kumar Y, Radha V, Swarup G.

J Biol Chem. 2017 Jan 27;292(4):1218-1230. doi: 10.1074/jbc.M116.763979. Epub 2016 Dec 14.

4.

Salmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation.

Hwang I, Park S, Hong S, Kim EH, Yu JW.

Immune Netw. 2012 Dec;12(6):284-90. doi: 10.4110/in.2012.12.6.284. Epub 2012 Dec 31.

5.

The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ.

Biochem J. 2013 Feb 1;449(3):613-21. doi: 10.1042/BJ20121198.

6.

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

Suzuki S, Franchi L, He Y, Muñoz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Núñez G.

PLoS Pathog. 2014 Feb 6;10(2):e1003926. doi: 10.1371/journal.ppat.1003926. eCollection 2014 Feb.

7.

The Relationship between NALP3 and Autoinflammatory Syndromes.

Campbell L, Raheem I, Malemud CJ, Askari AD.

Int J Mol Sci. 2016 May 13;17(5). pii: E725. doi: 10.3390/ijms17050725. Review.

8.

A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.

Moghaddas F, Llamas R, De Nardo D, Martinez-Banaclocha H, Martinez-Garcia JJ, Mesa-Del-Castillo P, Baker PJ, Gargallo V, Mensa-Vilaro A, Canna S, Wicks IP, Pelegrin P, Arostegui JI, Masters SL.

Ann Rheum Dis. 2017 Dec;76(12):2085-2094. doi: 10.1136/annrheumdis-2017-211473. Epub 2017 Aug 23.

9.

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.

Jabir MS, Hopkins L, Ritchie ND, Ullah I, Bayes HK, Li D, Tourlomousis P, Lupton A, Puleston D, Simon AK, Bryant C, Evans TJ.

Autophagy. 2015;11(1):166-82. doi: 10.4161/15548627.2014.981915.

10.

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Man SM, Hopkins LJ, Nugent E, Cox S, Glück IM, Tourlomousis P, Wright JA, Cicuta P, Monie TP, Bryant CE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7403-8. doi: 10.1073/pnas.1402911111. Epub 2014 May 6.

11.

Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4.

Van Opdenbosch N, Van Gorp H, Verdonckt M, Saavedra PHV, de Vasconcelos NM, Gonçalves A, Vande Walle L, Demon D, Matusiak M, Van Hauwermeiren F, D'Hont J, Hochepied T, Krautwald S, Kanneganti TD, Lamkanfi M.

Cell Rep. 2017 Dec 19;21(12):3427-3444. doi: 10.1016/j.celrep.2017.11.088.

12.

Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis.

Domiciano TP, Wakita D, Jones HD, Crother TR, Verri WA Jr, Arditi M, Shimada K.

Sci Rep. 2017 Feb 2;7:41539. doi: 10.1038/srep41539.

13.

Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4.

Hwang I, Yang J, Hong S, Ju Lee E, Lee SH, Fernandes-Alnemri T, Alnemri ES, Yu JW.

Immunol Cell Biol. 2015 Jul;93(6):591-9. doi: 10.1038/icb.2014.125. Epub 2015 Jan 20.

14.

β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.

Mao K, Chen S, Wang Y, Zeng Y, Ma Y, Hu Y, Zhang H, Sun S, Wu X, Meng G, Pei G, Sun B.

J Immunol. 2015 Feb 15;194(4):1867-73. doi: 10.4049/jimmunol.1401989. Epub 2015 Jan 12.

15.

Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila.

Case CL, Roy CR.

MBio. 2011 Sep 1;2(4). pii: e00117-11. doi: 10.1128/mBio.00117-11. Print 2011.

16.

Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.

Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M.

J Immunol. 2010 Jul 15;185(2):1186-95. doi: 10.4049/jimmunol.1001058. Epub 2010 Jun 21.

17.

Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death.

Kumar Y, Radha V, Swarup G.

Biochem J. 2010 Mar 15;427(1):91-104. doi: 10.1042/BJ20091349.

PMID:
20085538
18.

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.

Romberg N, Al Moussawi K, Nelson-Williams C, Stiegler AL, Loring E, Choi M, Overton J, Meffre E, Khokha MK, Huttner AJ, West B, Podoltsev NA, Boggon TJ, Kazmierczak BI, Lifton RP.

Nat Genet. 2014 Oct;46(10):1135-1139. doi: 10.1038/ng.3066. Epub 2014 Sep 14.

19.

NLRC3 protein inhibits inflammation by disrupting NALP3 inflammasome assembly via competition with the adaptor protein ASC for pro-caspase-1 binding.

Eren E, Berber M, Özören N.

J Biol Chem. 2017 Jul 28;292(30):12691-12701. doi: 10.1074/jbc.M116.769695. Epub 2017 Jun 5.

20.

Contribution of the inflammasome to inflammaging.

Mejias NH, Martinez CC, Stephens ME, de Rivero Vaccari JP.

J Inflamm (Lond). 2018 Nov 16;15:23. doi: 10.1186/s12950-018-0198-3. eCollection 2018.

Supplemental Content

Support Center