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Single nucleotide polymorphisms in long noncoding RNA, ANRIL, are not associated with severe periodontitis but with adverse cardiovascular events among patients with cardiovascular disease.

Schulz S, Seitter L, Werdan K, Hofmann B, Schaller HG, Schlitt A, Reichert S.

J Periodontal Res. 2018 Oct;53(5):714-720. doi: 10.1111/jre.12555. Epub 2018 May 6.


Association of ANRIL gene polymorphisms with major adverse cardiovascular events in hemodialysis patients.

Arbiol-Roca A, Padró-Miquel A, Hueso M, Navarro E, Alía-Ramos P, González-Álvarez MT, Rama I, Torras J, Grinyó JM, Cruzado JM, Lloberas N.

Clin Chim Acta. 2017 Mar;466:61-67. doi: 10.1016/j.cca.2016.12.029. Epub 2017 Jan 2. Erratum in: Clin Chim Acta. 2017 Aug;471:94.


A Lead ANRIL Polymorphism Is Associated with Elevated CRP Levels in Periodontitis: A Pilot Case-Control Study.

Teeuw WJ, Laine ML, Bizzarro S, Loos BG.

PLoS One. 2015 Sep 8;10(9):e0137335. doi: 10.1371/journal.pone.0137335. eCollection 2015.


The ANRIL Genetic Variants and Their Interactions with Environmental Risk Factors on Atherothrombotic Stroke in a Han Chinese Population.

Xiong L, Liu W, Gao L, Mu Q, Liu X, Feng Y, Tang Z, Tang H, Liu H.

J Stroke Cerebrovasc Dis. 2018 Sep;27(9):2336-2347. doi: 10.1016/j.jstrokecerebrovasdis.2018.04.020.


C-reactive protein levels and genetic variants of CRP as prognostic markers for combined cardiovascular endpoint (cardiovascular death, death from stroke, myocardial infarction, and stroke/TIA).

Schulz S, Lüdike H, Lierath M, Schlitt A, Werdan K, Hofmann B, Gläser C, Schaller HG, Reichert S.

Cytokine. 2016 Dec;88:71-76. doi: 10.1016/j.cyto.2016.08.021. Epub 2016 Aug 28.


Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk.

Cheng J, Cai MY, Chen YN, Li ZC, Tang SS, Yang XL, Chen C, Liu X, Xiong XD.

Oncotarget. 2017 Feb 21;8(8):12607-12619. doi: 10.18632/oncotarget.14721.


Soluble form of receptor for advanced glycation end products and incidence of new cardiovascular events among patients with cardiovascular disease.

Reichert S, Triebert U, Santos AN, Hofmann B, Schaller HG, Schlitt A, Schulz S.

Atherosclerosis. 2017 Nov;266:234-239. doi: 10.1016/j.atherosclerosis.2017.08.015. Epub 2017 Aug 23.


Homocysteine concentration in coronary artery disease: Influence of three common single nucleotide polymorphisms.

Bickel C, Schnabel RB, Zengin E, Lubos E, Rupprecht H, Lackner K, Proust C, Tregouet D, Blankenberg S, Westermann D, Sinning C.

Nutr Metab Cardiovasc Dis. 2017 Feb;27(2):168-175. doi: 10.1016/j.numecd.2016.09.005. Epub 2016 Sep 17.


Association of ALOX12 gene polymorphism with all-cause and cardiovascular mortality in diabetic nephropathy.

Roumeliotis AK, Roumeliotis SK, Panagoutsos SA, Tsetsos F, Georgitsi M, Manolopoulos V, Paschou P, Passadakis PS.

Int Urol Nephrol. 2018 Feb;50(2):321-329. doi: 10.1007/s11255-017-1755-z. Epub 2017 Dec 1.


Polymorphism in ANRIL is associated with relapse in patients with multiple myeloma after autologous stem cell transplant.

Poi MJ, Li J, Sborov DW, VanGundy Z, Cho YK, Lamprecht M, Pichiorri F, Phelps MA, Hofmeister CC.

Mol Carcinog. 2017 Jul;56(7):1722-1732. doi: 10.1002/mc.22626. Epub 2017 Feb 16.


Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B.

Congrains A, Kamide K, Oguro R, Yasuda O, Miyata K, Yamamoto E, Kawai T, Kusunoki H, Yamamoto H, Takeya Y, Yamamoto K, Onishi M, Sugimoto K, Katsuya T, Awata N, Ikebe K, Gondo Y, Oike Y, Ohishi M, Rakugi H.

Atherosclerosis. 2012 Feb;220(2):449-55. doi: 10.1016/j.atherosclerosis.2011.11.017. Epub 2011 Nov 19.


Regulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.

Bai Y, Nie S, Jiang G, Zhou Y, Zhou M, Zhao Y, Li S, Wang F, Lv Q, Huang Y, Yang Q, Li Q, Li Y, Xia Y, Liu Y, Liu J, Qian J, Li B, Wu G, Wu Y, Wang B, Cheng X, Yang Y, Ke T, Li H, Ren X, Ma X, Liao Y, Xu C, Tu X, Wang QK.

Stroke. 2014 Feb;45(2):383-8. doi: 10.1161/STROKEAHA.113.003393. Epub 2014 Jan 2.


Additive effect of ANRIL and BRAP polymorphisms on ankle-brachial index in a Taiwanese population.

Tsai PC, Liao YC, Lin TH, Hsi E, Yang YH, Juo SH.

Circ J. 2012;76(2):446-52. Epub 2011 Nov 27.


Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.

Schaefer AS, Richter GM, Groessner-Schreiber B, Noack B, Nothnagel M, El Mokhtari NE, Loos BG, Jepsen S, Schreiber S.

PLoS Genet. 2009 Feb;5(2):e1000378. doi: 10.1371/journal.pgen.1000378. Epub 2009 Feb 13.


Diagnostic value of circulating lncRNA ANRIL and its correlation with coronary artery disease parameters.

Hu Y, Hu J.

Braz J Med Biol Res. 2019;52(8):e8309. doi: 10.1590/1414-431X20198309. Epub 2019 Aug 12.


The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

Bochenek G, Häsler R, El Mokhtari NE, König IR, Loos BG, Jepsen S, Rosenstiel P, Schreiber S, Schaefer AS.

Hum Mol Genet. 2013 Nov 15;22(22):4516-27. doi: 10.1093/hmg/ddt299. Epub 2013 Jun 27.


Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis.

Davis LA, Cannon GW, Pointer LF, Haverhals LM, Wolff RK, Mikuls TR, Reimold AM, Kerr GS, Richards JS, Johnson DS, Valuck R, Prochazka A, Caplan L.

J Rheumatol. 2013 Jun;40(6):809-17. doi: 10.3899/jrheum.121012. Epub 2013 Apr 1.


Data on genotypic distribution and linkage disequilibrium of several ANRIL polymorphisms in hemodialysis patients.

Arbiol-Roca A, Padró-Miquel A, Hueso M, Navarro E, Alía-Ramos P, González-Álvarez MT, Rama I, Torras J, Grinyó JM, Cruzado JM, Lloberas N.

Data Brief. 2017 Feb 12;11:221-224. doi: 10.1016/j.dib.2017.02.011. eCollection 2017 Apr.


Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.

Carty CL, Buzková P, Fornage M, Franceschini N, Cole S, Heiss G, Hindorff LA, Howard BV, Mann S, Martin LW, Zhang Y, Matise TC, Prentice R, Reiner AP, Kooperberg C.

Circ Cardiovasc Genet. 2012 Apr 1;5(2):210-6. doi: 10.1161/CIRCGENETICS.111.962191. Epub 2012 Mar 8. Erratum in: Circ Cardiovasc Genet. 2013 Aug;6(4):e10.


Methylation of p15INK4b and expression of ANRIL on chromosome 9p21 are associated with coronary artery disease.

Zhuang J, Peng W, Li H, Wang W, Wei Y, Li W, Xu Y.

PLoS One. 2012;7(10):e47193. doi: 10.1371/journal.pone.0047193. Epub 2012 Oct 16.

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