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Items: 1 to 20 of 114

1.

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3.

Schmidt A, Marabita F, Kiani NA, Gross CC, Johansson HJ, Éliás S, Rautio S, Eriksson M, Fernandes SJ, Silberberg G, Ullah U, Bhatia U, Lähdesmäki H, Lehtiö J, Gomez-Cabrero D, Wiendl H, Lahesmaa R, Tegnér J.

BMC Biol. 2018 May 7;16(1):47. doi: 10.1186/s12915-018-0518-3.

2.
3.

Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation.

Freudenberg K, Lindner N, Dohnke S, Garbe AI, Schallenberg S, Kretschmer K.

Front Immunol. 2018 Feb 2;9:125. doi: 10.3389/fimmu.2018.00125. eCollection 2018.

4.

Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate.

Schmidt A, Eriksson M, Shang MM, Weyd H, Tegnér J.

PLoS One. 2016 Feb 17;11(2):e0148474. doi: 10.1371/journal.pone.0148474. eCollection 2016.

5.

IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo.

Chen Q, Kim YC, Laurence A, Punkosdy GA, Shevach EM.

J Immunol. 2011 Jun 1;186(11):6329-37. doi: 10.4049/jimmunol.1100061. Epub 2011 Apr 27.

6.

All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus.

Lu L, Ma J, Li Z, Lan Q, Chen M, Liu Y, Xia Z, Wang J, Han Y, Shi W, Quesniaux V, Ryffel B, Brand D, Li B, Liu Z, Zheng SG.

PLoS One. 2011;6(9):e24590. doi: 10.1371/journal.pone.0024590. Epub 2011 Sep 13.

7.

Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.

Knosp CA, Schiering C, Spence S, Carroll HP, Nel HJ, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald DC, Powrie F, Fallon PG, Johnston JA, Kissenpfennig A.

J Immunol. 2013 Apr 1;190(7):3235-45. doi: 10.4049/jimmunol.1201396. Epub 2013 Mar 1.

8.

Delta-like 1-mediated Notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells.

Mota C, Nunes-Silva V, Pires AR, Matoso P, Victorino RM, Sousa AE, Caramalho I.

J Immunol. 2014 Dec 15;193(12):5854-62. doi: 10.4049/jimmunol.1400198. Epub 2014 Nov 3.

9.

TNF-α impairs differentiation and function of TGF-β-induced Treg cells in autoimmune diseases through Akt and Smad3 signaling pathway.

Zhang Q, Cui F, Fang L, Hong J, Zheng B, Zhang JZ.

J Mol Cell Biol. 2013 Apr;5(2):85-98. doi: 10.1093/jmcb/mjs063. Epub 2012 Dec 12.

PMID:
23243069
10.

A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells.

Guo Z, Khattar M, Schroder PM, Miyahara Y, Wang G, He X, Chen W, Stepkowski SM.

J Immunol. 2013 Apr 1;190(7):3153-62. doi: 10.4049/jimmunol.1200751. Epub 2013 Feb 20.

11.

Regulatory T-Cell (Treg) hybridoma as a novel tool to study Foxp3 regulation and Treg fate.

Sharma R, Sung SS, Ju CY, Deshmukh US, Fu SM, Ju ST.

J Autoimmun. 2011 Sep;37(2):113-21. doi: 10.1016/j.jaut.2011.05.008. Epub 2011 May 31.

12.

A Cellular MicroRNA Facilitates Regulatory T Lymphocyte Development by Targeting the FOXP3 Promoter TATA-Box Motif.

Zhang Y, Liu W, Chen Y, Liu J, Wu K, Su L, Zhang W, Jiang Y, Zhang X, Zhang Y, Liu C, Tao L, Liu B, Zhang H.

J Immunol. 2018 Feb 1;200(3):1053-1063. doi: 10.4049/jimmunol.1700196. Epub 2017 Dec 27.

13.

Role of TGF-Beta in the induction of Foxp3 expression and T regulatory cell function.

Shevach EM, Davidson TS, Huter EN, Dipaolo RA, Andersson J.

J Clin Immunol. 2008 Nov;28(6):640-6. doi: 10.1007/s10875-008-9240-1. Epub 2008 Sep 23.

PMID:
18810612
14.

Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3⁺ Treg cells.

Verhagen J, Wraith DC.

J Immunol Methods. 2014 Dec 1;414:58-64. doi: 10.1016/j.jim.2014.07.012. Epub 2014 Aug 6.

15.

Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance.

Kong N, Lan Q, Chen M, Wang J, Shi W, Horwitz DA, Quesniaux V, Ryffel B, Liu Z, Brand D, Zou H, Zheng SG.

Arthritis Rheum. 2012 Aug;64(8):2548-58. doi: 10.1002/art.34513.

16.

Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells.

Liu Y, Lan Q, Lu L, Chen M, Xia Z, Ma J, Wang J, Fan H, Shen Y, Ryffel B, Brand D, Quismorio F, Liu Z, Horwitz DA, Xu A, Zheng SG.

J Mol Cell Biol. 2014 Feb;6(1):81-92. doi: 10.1093/jmcb/mjt026. Epub 2013 Jul 15.

17.

Natural and inducible Tregs in swine: Helios expression and functional properties.

Käser T, Mair KH, Hammer SE, Gerner W, Saalmüller A.

Dev Comp Immunol. 2015 Apr;49(2):323-31. doi: 10.1016/j.dci.2014.12.005. Epub 2014 Dec 12.

PMID:
25511662
18.

Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells.

Ubaid Ullah, Andrabi SBA, Tripathi SK, Dirasantha O, Kanduri K, Rautio S, Gross CC, Lehtimäki S, Bala K, Tuomisto J, Bhatia U, Chakroborty D, Elo LL, Lähdesmäki H, Wiendl H, Rasool O, Lahesmaa R.

Cell Rep. 2018 Feb 20;22(8):2094-2106. doi: 10.1016/j.celrep.2018.01.070.

19.

A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta.

Selvaraj RK, Geiger TL.

J Immunol. 2007 Jul 15;179(2):11 p following 1390.

20.

Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region.

Rossetti M, Spreafico R, Saidin S, Chua C, Moshref M, Leong JY, Tan YK, Thumboo J, van Loosdregt J, Albani S.

J Immunol. 2015 Jan 1;194(1):113-24. doi: 10.4049/jimmunol.1401145. Epub 2014 Dec 1.

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