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Items: 1 to 20 of 78

1.

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging.

Mihaylova MM, Cheng CW, Cao AQ, Tripathi S, Mana MD, Bauer-Rowe KE, Abu-Remaileh M, Clavain L, Erdemir A, Lewis CA, Freinkman E, Dickey AS, La Spada AR, Huang Y, Bell GW, Deshpande V, Carmeliet P, Katajisto P, Sabatini DM, Yilmaz ÖH.

Cell Stem Cell. 2018 May 3;22(5):769-778.e4. doi: 10.1016/j.stem.2018.04.001.

PMID:
29727683
2.

A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity.

Knobloch M, Pilz GA, Ghesquière B, Kovacs WJ, Wegleiter T, Moore DL, Hruzova M, Zamboni N, Carmeliet P, Jessberger S.

Cell Rep. 2017 Aug 29;20(9):2144-2155. doi: 10.1016/j.celrep.2017.08.029.

3.

Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy.

Tan Z, Xiao L, Tang M, Bai F, Li J, Li L, Shi F, Li N, Li Y, Du Q, Lu J, Weng X, Yi W, Zhang H, Fan J, Zhou J, Gao Q, Onuchic JN, Bode AM, Luo X, Cao Y.

Theranostics. 2018 Mar 22;8(9):2329-2347. doi: 10.7150/thno.21451. eCollection 2018.

4.

Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging.

Koehler CL, Perkins GA, Ellisman MH, Jones DL.

J Cell Biol. 2017 Aug 7;216(8):2315-2327. doi: 10.1083/jcb.201610036. Epub 2017 Jun 29.

5.

Dietary Regulation of Adult Stem Cells.

Mana MD, Kuo EY, Yilmaz ÖH.

Curr Stem Cell Rep. 2017 Mar;3(1):1-8. doi: 10.1007/s40778-017-0072-x. Epub 2017 Feb 8.

6.

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.

Kalucka J, Bierhansl L, Conchinha NV, Missiaen R, Elia I, Brüning U, Scheinok S, Treps L, Cantelmo AR, Dubois C, de Zeeuw P, Goveia J, Zecchin A, Taverna F, Morales-Rodriguez F, Brajic A, Conradi LC, Schoors S, Harjes U, Vriens K, Pilz GA, Chen R, Cubbon R, Thienpont B, Cruys B, Wong BW, Ghesquière B, Dewerchin M, De Bock K, Sagaert X, Jessberger S, Jones EAV, Gallez B, Lambrechts D, Mazzone M, Eelen G, Li X, Fendt SM, Carmeliet P.

Cell Metab. 2018 Dec 4;28(6):881-894.e13. doi: 10.1016/j.cmet.2018.07.016. Epub 2018 Aug 23.

PMID:
30146488
7.

Localized intestinal radiation and liquid diet enhance survival and permit evaluation of long-term intestinal responses to high dose radiation in mice.

Van Landeghem L, Blue RE, Dehmer JJ, Henning SJ, Helmrath MA, Lund PK.

PLoS One. 2012;7(12):e51310. doi: 10.1371/journal.pone.0051310. Epub 2012 Dec 7.

8.

The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment.

Cedeno RJ, Nakauka-Ddamba A, Yousefi M, Sterling S, Leu NA, Li N, Pehrson JR, Lengner CJ.

PLoS One. 2017 Sep 21;12(9):e0185196. doi: 10.1371/journal.pone.0185196. eCollection 2017.

9.

Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export.

Seifert EL, Bézaire V, Estey C, Harper ME.

J Biol Chem. 2008 Sep 12;283(37):25124-31. doi: 10.1074/jbc.M803871200. Epub 2008 Jul 14.

10.

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation.

Orellana-Gavaldà JM, Herrero L, Malandrino MI, Pañeda A, Sol Rodríguez-Peña M, Petry H, Asins G, Van Deventer S, Hegardt FG, Serra D.

Hepatology. 2011 Mar;53(3):821-32. doi: 10.1002/hep.24140. Epub 2011 Feb 11.

PMID:
21319201
11.

Drosophila PEBP1 inhibits intestinal stem cell aging via suppression of ERK pathway.

Pyo JH, Jeon HJ, Park JS, Lee JS, Chung HY, Yoo MA.

Oncotarget. 2018 Apr 6;9(26):17980-17993. doi: 10.18632/oncotarget.24834. eCollection 2018 Apr 6.

12.

Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses.

Namgaladze D, Lips S, Leiker TJ, Murphy RC, Ekroos K, Ferreiros N, Geisslinger G, Brüne B.

Diabetologia. 2014 May;57(5):1067-77. doi: 10.1007/s00125-014-3173-4. Epub 2014 Feb 1.

PMID:
24488024
13.

Regulation of mitochondrial fatty acid β-oxidation in human: what can we learn from inborn fatty acid β-oxidation deficiencies?

Bastin J.

Biochimie. 2014 Jan;96:113-20. doi: 10.1016/j.biochi.2013.05.012. Epub 2013 Jun 10. Review.

PMID:
23764392
14.

The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders.

Houten SM, Violante S, Ventura FV, Wanders RJ.

Annu Rev Physiol. 2016;78:23-44. doi: 10.1146/annurev-physiol-021115-105045. Epub 2015 Oct 14. Review.

PMID:
26474213
15.

PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition.

Ramakrishnan SK, Khuder SS, Al-Share QY, Russo L, Abdallah SL, Patel PR, Heinrich G, Muturi HT, Mopidevi BR, Oyarce AM, Shah YM, Sanchez ER, Najjar SM.

J Biol Chem. 2016 Apr 8;291(15):8121-9. doi: 10.1074/jbc.M116.714014. Epub 2016 Feb 4.

16.

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.

Yilmaz ÖH, Katajisto P, Lamming DW, Gültekin Y, Bauer-Rowe KE, Sengupta S, Birsoy K, Dursun A, Yilmaz VO, Selig M, Nielsen GP, Mino-Kenudson M, Zukerberg LR, Bhan AK, Deshpande V, Sabatini DM.

Nature. 2012 Jun 28;486(7404):490-5. doi: 10.1038/nature11163.

17.

Rac1 drives intestinal stem cell proliferation and regeneration.

Myant KB, Scopelliti A, Haque S, Vidal M, Sansom OJ, Cordero JB.

Cell Cycle. 2013 Sep 15;12(18):2973-7. doi: 10.4161/cc.26031. Epub 2013 Aug 12.

18.

Dietary fat sensing via fatty acid oxidation in enterocytes: possible role in the control of eating.

Langhans W, Leitner C, Arnold M.

Am J Physiol Regul Integr Comp Physiol. 2011 Mar;300(3):R554-65. doi: 10.1152/ajpregu.00610.2010. Epub 2010 Dec 9. Review.

19.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
20.

High-fat feeding in cardiomyocyte-restricted PPARdelta knockout mice leads to cardiac overexpression of lipid metabolic genes but fails to rescue cardiac phenotypes.

Li Y, Cheng L, Qin Q, Liu J, Lo WK, Brako LA, Yang Q.

J Mol Cell Cardiol. 2009 Oct;47(4):536-43. doi: 10.1016/j.yjmcc.2009.07.001. Epub 2009 Jul 9.

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